{"result":[{"lastName":"Kao","clinicalFocus":[{"focus":"Pulmonary Disease"},{"focus":"Pulmonology (Lung) and Critical Care "}],"appointments":[{"appointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine"}],"primaryAppointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5961&type=small&showNoImage","displayName":"Peter Kao","firstName":"Peter","href":"http://med.stanford.edu/profiles/Peter_Kao","researchInterest":"Our research program has several active projects:\r\n1.) Pulmonary Vascular Disease \u0096 Simvastatin reversed experimental pulmonary hypertension, and is safe for treatment of patients. Blinded clinical trials of efficacy are in progress.\r\n2.) Lung inflammation and regeneration (stem cells)\r\n3.) Lung surfactant rheology and oxidative stress\r\n4.) Gene regulation by RNA binding proteins, NF45 and NF90 through transcriptional and posttranscriptional mechanisms"},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Weill","clinicalFocus":[{"focus":"Pulmonary Critical Care"},{"focus":"Pulmonary Disease"}],"appointments":[{"appointment":"Professor - Med Center Line,Medicine - Pulmonary & Critical Care Medicine"}],"primaryAppointment":"Professor - Med Center Line,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7227&type=small&showNoImage","displayName":"David Weill","firstName":"David","href":"http://med.stanford.edu/profiles/David_Weill","researchInterest":""},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Wei","clinicalFocus":[{"focus":"Hematology/Oncology/Stem Cell Transplant,  Pediatric"},{"focus":"Pediatric Hematology-Oncology"}],"appointments":[{"appointment":"Instructor,Pediatrics - Hematology & Oncology"}],"primaryAppointment":"Instructor,Pediatrics - Hematology & Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8537&type=small&showNoImage","displayName":"Michael Wei, MD, PhD","firstName":"Michael","href":"http://med.stanford.edu/profiles/Michael_Wei","researchInterest":""},{"lastName":"Boxer","clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4658&type=small&showNoImage","displayName":"Linda Boxer","firstName":"Linda","href":"http://med.stanford.edu/profiles/Linda_Boxer","researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells."},{"lastName":"Krams","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor (Research),Surgery - Multi-Organ Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4475&type=small&showNoImage","displayName":"Sheri Krams","firstName":"Sheri","href":"http://med.stanford.edu/profiles/Sheri_Krams","researchInterest":"Our recent studies have focused on three specific areas: 1) NK cell interactions with dendritic cells and tumors, 2) MicroRNAs as master regulators in transplantation and viral infections and 3) Mechanisms of tolerance induction."},{"lastName":"Sussman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4097&type=small&showNoImage","displayName":"Howard Sussman","firstName":"Howard","href":"http://med.stanford.edu/profiles/Howard_Sussman","researchInterest":"The general problem with which we are concerned is the elucidation of cellular mechanisms of gene regulation which are related to the neoplastic process in humans. The phenomenon of ectopic protein synthesis in human cancer offers a good experimental model for investigating this problem."},{"lastName":"Michie","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4707&type=small&showNoImage","displayName":"Sara Michie","firstName":"Sara","href":"http://med.stanford.edu/profiles/Sara_Michie","researchInterest":"Lymphocyte/endothelial cell adhesion mechanisms involved in lymphocyte migration to sites of inflammation; regulation of expression of endothelial cell adhesion molecules."},{"lastName":"Martinez","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor (Research),Surgery - Multi-Organ Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4474&type=small&showNoImage","displayName":"Olivia Martinez","firstName":"Olivia","href":"http://med.stanford.edu/profiles/Olivia_Martinez","researchInterest":"EBV B cell lymphomas; pathways of immune evasion in the growth and survival of EBV B cell lymphomas;  mechanisms of graft rejection and tolerance induction; stem cell and solid organ transplantation."},{"lastName":"Diehn","clinicalFocus":[{"focus":"Radiation Oncology"},{"focus":"Radiation Therapy"}],"appointments":[{"appointment":"Assistant Professor,Radiation Oncology - Radiation Therapy"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor,Radiation Oncology - Radiation Therapy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9248&type=small&showNoImage","displayName":"Maximilian Diehn, M.D., Ph.D.","firstName":"Maximilian","href":"http://med.stanford.edu/profiles/Maximilian_Diehn","researchInterest":"My laboratory studies cancer stem cell biology and its implications for therapy. We are interested in developing a deeper molecular understanding of breast cancer and lung cancer stem cells, including identifying pathways and genes important for survival and self renewal. Additionally, we are developing methods for overcoming resistance mechanisms to radiotherapy and chemotherapy in cancer stem cells. Clinically I specialize in the treatment of lung cancer and applications of radiosurgery."},{"lastName":"Whyte","clinicalFocus":[],"appointments":[{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Member,Stanford Cancer Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4435&type=small&showNoImage","displayName":"Richard Whyte","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Whyte","researchInterest":"clinical lung and esophageal cancer treatment studies, lung transplantation, surgical ,management of emphysema."},{"lastName":"O'Brodovich","clinicalFocus":[{"focus":"Pediatric Pulmonary"},{"focus":"Pulmonary Medicine/Cystic Fibrosis, Pediatric"}],"appointments":[{"appointment":"Professor,Pediatrics"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor,Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8414&type=small&showNoImage","displayName":"Hugh O'Brodovich","firstName":"Hugh","href":"http://med.stanford.edu/profiles/Hugh_O'Brodovich","researchInterest":"Clinical: \r\nPulmonary edema, acute respiratory distress syndromes (ARDS), hyaline membrane disease (HMD), bronchopulmonary dysplasia (BPD)\r\n\r\nBasic Science: \r\nLung epithelial sodium transport\r\nGenetic influences on the development of BPD"},{"lastName":"Peltz","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8527&type=small&showNoImage","displayName":"Gary Peltz","firstName":"Gary","href":"http://med.stanford.edu/profiles/Gary_Peltz","researchInterest":"The laboratory develops and uses state of the art genomic methods to identify genetic factors affecting disease susceptibility, and to translate these findings into new treatments. We have developed a more efficient method for performing mouse genetic analysis, which has been used to analyze the genetic basis for 16 different biomedical traits. We are developing novel methods, and have developed a novel experimental platform that replaces mouse liver with functioning human liver tissue."},{"lastName":"Sadaghiani","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19931&type=small&showNoImage","displayName":"A. Masoud Sadaghiani","firstName":"Amir","href":"http://med.stanford.edu/profiles/Amir_Sadaghiani","researchInterest":""},{"lastName":"Donington","clinicalFocus":[],"appointments":[{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Member,Stanford Cancer Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3919&type=small&showNoImage","displayName":"Jessica Donington","firstName":"Jessica","href":"http://med.stanford.edu/profiles/Jessica_Donington","researchInterest":"Lung Cancer, Thoracic Cancers - Surgical Oncology, Esophageal Cancer"},{"lastName":"Shrager","clinicalFocus":[{"focus":"Thoracic Cancers - Thoracic Surgery"},{"focus":"Thoracic Surgery"},{"focus":"Thoracic Surgery, Video-Assisted"},{"focus":"Lung Cancer"},{"focus":"Thoracoscopy"},{"focus":"VATS"},{"focus":"Thymoma"},{"focus":"Mediastinal Diseases"},{"focus":"Mediastinal Cyst"},{"focus":"Myasthenia Gravis"},{"focus":"Thymectomy"},{"focus":"Surgical Procedures, Minimally Invasive"},{"focus":"Emphysema Surgery"},{"focus":"Lung Volume Reduction"},{"focus":"Bullectomy"},{"focus":"Sympathectomy"},{"focus":"Esophageal Cancer"},{"focus":"Pneumothorax"},{"focus":"Pleural Diseases"},{"focus":"sarcoma"}],"appointments":[{"appointment":"Professor - Med Center Line,Cardiothoracic Surgery - Thoracic Surgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor - Med Center Line,Cardiothoracic Surgery - Thoracic Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8561&type=small&showNoImage","displayName":"Joseph Shrager","firstName":"Joseph","href":"http://med.stanford.edu/profiles/Joseph_Shrager","researchInterest":"In clinical research, Dr. Shrager has been an innovator studying outcomes in a variety of areas within Thoracic Surgery including: parenchyma-sparing operations and minimally invasive resections for lung cancer, transcervical thymectomy for myasthenia gravis, and surgical treatment of emphysema.\r\n\r\nIn the lab, Dr. Shrager is focused on the impact of disease states upon the diaphragm. His group published the seminal paper (NEJM) describing diaphragm atrophy assoc'd with mechanical ventilation."},{"lastName":"Dhillon","clinicalFocus":[{"focus":"Lung and Heart-Lung Transplantation"},{"focus":"Critical Care Medicine"},{"focus":"Pulmonary Disease"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Medicine - Pulmonary & Critical Care Medicine"}],"primaryAppointment":"Assistant Professor - Med Center Line,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7231&type=small&showNoImage","displayName":"Gundeep Dhillon, MD, MPH","firstName":"Gundeep","href":"http://med.stanford.edu/profiles/Gundeep_Dhillon","researchInterest":"1. Use of an administrative database (UNOS) to study lung transplant outcomes.\r\n2. Expression of the plasminogen activator inhibitor (PAI) 1 antibody in peripheral blood after lung transplantation and its association with bronchiolitis obliterans syndrome (chronic rejection).\r\n3. Impact of airway hypoxia, due to lack of bronchial circulation, on long-term lung transplant outcomes.\r\n4. CMV specific T-cell immunity in lung transplant recipients and its impact on acute rejection."},{"lastName":"Bonham","clinicalFocus":[{"focus":"General Surgery"},{"focus":"Liver Transplantation"},{"focus":"Live-donor Liver Transplantation"},{"focus":"Pediatric Transplantation"},{"focus":"Intestinal Transplantation"},{"focus":"Kidney and Pancreas Transplantation"},{"focus":"Portal Hypertension"},{"focus":"Hepatobiliary Surgery"},{"focus":"Cancer of Biliary Tract"},{"focus":"Cancer, Liver"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor - Med Center Line,Surgery - Multi-Organ Transplantation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3884&type=small&showNoImage","displayName":"Clark Bonham","firstName":"Clark","href":"http://med.stanford.edu/profiles/Clark_Bonham","researchInterest":"Tolerance induction in liver transplantation.\r\nHepatocyte transplantation."},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7143&type=small&showNoImage","displayName":"Albert J. Wong, M.D.","firstName":"Albert","href":"http://med.stanford.edu/profiles/Albert_Wong","researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring  mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective."},{"lastName":"Sibley","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology"}],"appointments":[{"appointment":"Professor,Pathology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4113&type=small&showNoImage","displayName":"Richard Sibley","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Sibley","researchInterest":"Immunologic mechanism of rejection in humans and animal, models of organ transplantation; histological definition of clinical pathology studies of various renal disorders."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Brown","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Emeritus Faculty, Acad Council,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor Emeritus,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4536&type=small&showNoImage","displayName":"Martin Brown","firstName":"Martin","href":"http://med.stanford.edu/profiles/Martin_Brown","researchInterest":"We seek to understand the mechanisms responsible for the resistance of cancers to treatment and to develop strategies to overcome these resistances. We are using molecular and cellular techniques and mouse models to potentiate the activity of radiation on tumors by inhibiting the bone marrow rescue of the tumor vasculature following therapy."}]}