Vinicio de Jesus Perez MD

Publications

• Understanding the Pharmacokinetics of Oral Treprostinil in Patients with Pulmonary Arterial Hypertension. de Jesus Perez VA, J Cardiovasc Pharmacol. 2013
• Loss of adenomatous poliposis coli-α3 integrin interaction promotes endothelial apoptosis in mice and humans. de Jesus Perez VA, Yuan K, Orcholski ME, Sawada H, Zhao M, Li CG, Tojais NF, Nickel N, Rajagopalan V, Spiekerkoetter E, Wang L, Dutta R, Bernstein D, Rabinovitch M. Circ Res. 2012; 111 (12): 1551-64
• BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways. Perez VA, Ali Z, Alastalo TP, Ikeno F, Sawada H, Lai YJ, Kleisli T, Spiekerkoetter E, Qu X, Rubinos LH, Ashley E, Amieva M, Dedhar S, Rabinovitch M. J Cell Biol. 2011; 192 (1): 171-88
• Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. de Jesus Perez VA, Alastalo TP, Wu JC, Axelrod JD, Cooke JP, Amieva M, Rabinovitch M. J Cell Biol. 2009; 184 (1): 83-99
• MicroRNAs: promising therapeutic targets for the treatment of pulmonary arterial hypertension. Yuan K, Orcholski M, Tian X, Liao X, de Jesus Perez VA. Expert Opin Ther Targets. 2013; 17 (5): 557-64
• Development of a recurrent pleural effusion in a patient with pulmonary arterial hypertension treated with imatinib Olga M. Fortenko, Lana Melendres-Groves, Alice Richter, Xiaobo Liao, Edda Spiekerkoetter, Roham Zamanian, Vinicio A. De Jesus Perez. Case Reports in Clinical Medicine. 2012; 1 (2): 38-41
• Diagnosis and management of pulmonary hypertension associated with left ventricular diastolic dysfunction de Jesus Perez, V, Haddad, F and Zamanian RT. Pulmonary Circulation. 2012; 2 (2): 163
• The intersection of genes and environment: development of pulmonary arterial hypertension in a patient with hereditary hemorrhagic telangiectasia and stimulant exposure. Ayala E, Kudelko KT, Haddad F, Zamanian RT, de Jesus Perez V. Chest. 2012; 141 (6): 1598-600
• Pulmonary hypertension associated with left heart disease: characteristics, emerging concepts, and treatment strategies. Haddad F, Kudelko K, Mercier O, Vrtovec B, Zamanian RT, de Jesus Perez V. Prog Cardiovasc Dis. 2011 Sep-Oct; 54 (2): 154-67
• Characteristics and outcome after hospitalization for acute right heart failure in patients with pulmonary arterial hypertension. Haddad F, Peterson T, Fuh E, Kudelko KT, de Jesus Perez V, Skhiri M, Vagelos R, Schnittger I, Denault AY, Rosenthal DN, Doyle RL, Zamanian RT. Circ Heart Fail. 2011; 4 (6): 692-9
• Chronic thromboembolic pulmonary hypertension. Perez VA, Zamanian RT. N Engl J Med. 2011; 364 (17): 1677; author reply 1678
• Disruption of PPARγ/β-catenin-mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival. Alastalo TP, Li M, Perez Vde J, Pham D, Sawada H, Wang JK, Koskenvuo M, Wang L, Freeman BA, Chang HY, Rabinovitch M. J Clin Invest. 2011; 121 (9): 3735-46
• Disruption of the apelin-APJ system worsens hypoxia-induced pulmonary hypertension. Chandra SM, Razavi H, Kim J, Agrawal R, Kundu RK, de Jesus Perez V, Zamanian RT, Quertermous T, Chun HJ. Arterioscler Thromb Vasc Biol. 2011; 31 (4): 814-20
• Drugs and toxins-associated pulmonary arterial hypertension: lessons learned and challenges ahead. de Jesus Perez V, Kudelko K, Snook S, Zamanian RT. Int J Clin Pract Suppl. 2011; (169): 8-10
• Incidence, correlates, and consequences of acute kidney injury in patients with pulmonary arterial hypertension hospitalized with acute right-side heart failure. Haddad F, Fuh E, Peterson T, Skhiri M, Kudelko KT, De Jesus Perez V, Winkelmayer WC, Doyle RL, Chertow GM, Zamanian RT. J Card Fail. 2011; 17 (7): 533-9
• Making Sense of the Estrogen Paradox in Pulmonary Arterial Hypertension vinicio de jesus perez, American Journal of Respiratory and Critical Care Medicine. 2011: 184 629
• Epoprostenol-associated pneumonitis: diagnostic use of a T-cell proliferation assay. Kudelko KT, Nadeau K, Leung AN, Liu J, Haddad F, Zamanian RT, De Jesus Perez V. J Heart Lung Transplant. 2010; 29 (9): 1071-5
• Angina associated with left main coronary artery compression in pulmonary hypertension. de Jesus Perez VA, Haddad F, Vagelos RH, Fearon W, Feinstein J, Zamanian RT. J Heart Lung Transplant. 2009; 28 (5): 527-30
• Cholinergic modulation of angiogenesis: role of the 7 nicotinic acetylcholine receptor. Wu JC, Chruscinski A, De Jesus Perez VA, Singh H, Pitsiouni M, Rabinovitch M, Utz PJ, Cooke JP. J Cell Biochem. 2009; 108 (2): 433-46
• S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4. Spiekerkoetter E, Guignabert C, de Jesus Perez V, Alastalo TP, Powers JM, Wang L, Lawrie A, Ambartsumian N, Schmidt AM, Berryman M, Ashley RH, Rabinovitch M. Circ Res. 2009; 105 (7): 639-47, 13 p following 647
• An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension. Hansmann G, de Jesus Perez VA, Alastalo TP, Alvira CM, Guignabert C, Bekker JM, Schellong S, Urashima T, Wang L, Morrell NW, Rabinovitch M. J Clin Invest. 2008; 118 (5): 1846-57
• Coexistence of Primary adenocarcinoma of the lung and Tsukamurella pneumonia: a case report and review of the literature de Jesus Perez, VA, Swigris J, Ruoss, S. Journal of Medical Case Reports. 2008; 207 (2)
• Pulmonary arterial hypertension is linked to insulin resistance and reversed by peroxisome proliferator-activated receptor-gamma activation. Hansmann G, Wagner RA, Schellong S, Perez VA, Urashima T, Wang L, Sheikh AY, Suen RS, Stewart DJ, Rabinovitch M. Circulation. 2007; 115 (10): 1275-84