Lorrin Koran
Publication Details
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Rapid benefit of intravenous pulse loading of clomipramine in obsessive-compulsive disorder.
Am J Psychiatry. 1997; (3): 396-401
The authors conducted a randomized, double-blind, placebo-controlled trial of intravenous versus oral pulse loading of clomipramine in patients with obsessive-compulsive disorder to test two hypotheses: 1) intravenous pulse loading will cause greater immediate improvement than oral pulse loading and 2) patients who respond to pulse loading will continue to improve during 8 weeks of oral clomipramine treatment.
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