Ira D Glick

Publication Details

• Patterns of concomitant psychotropic medication use during a 2-year study comparing clozapine and olanzapine for the prevention of suicidal behavior.

  Glick ID, Zaninelli R, Hsu C, Young FK, Weiss L, Gunay I, Kumar V. J Clin Psychiatry. 2004; 65 (5): 679-85

  Results from the International Suicide Prevention Trial (InterSePT) indicate that clozapine is more effective than olanzapine in reducing suicidal behavior in schizophrenic and schizoaffective patients. However, because InterSePT allowed the uncontrolled use of concomitant psychotropic medications (CPMs), it is possible that the antisuicidal effect of clozapine may have been influenced by greater use of such agents. This article describes the use patterns of CPMs during InterSePT and examines whether CPM use may have affected study outcome.

  PubMedID: 15163255