Jerome Yesavage

Publication Details

• Decreased daytime motor activity associated with apathy in Alzheimer disease: an actigraphic study.

  David R, Mulin E, Friedman L, Le Duff F, Cygankiewicz E, Deschaux O, Garcia R, Yesavage JA, Robert PH, Zeitzer JM. Am J Geriatr Psychiatry. 2012; 20 (9): 806-14

  Across all stages of Alzheimer disease (AD), apathy is the most common neuropsychiatric symptom. Studies using the Neuropsychiatric Inventory (NPI) have found that apathy is present in up to 70% of individuals with Alzheimer disease. One of the main difficulties in assessing apathy and other neuropsychiatric symptoms is the absence of reliable, objective measures. Motor activity assessment using ambulatory actigraphy could provide an indirect, objective evaluation of apathy. The aim of our study was to assess the relationship between apathy and daytime motor activity in AD, using ambulatory actigraphy.

  PubMedID: 21997602