Trisha Suppes, MD, PhD
Publication Details
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Effects of clozapine on sleep in bipolar and schizoaffective disorders.
Prog Neuropsychopharmacol Biol Psychiatry. 2004; (7): 1065-70
Sleep disturbances are strongly associated with mood disorders, although the majority of data have been obtained in patients with major depressive disorder. Studies reporting results in bipolar disorder are few, and results have not been consistent. Clozapine is a prototype of atypical antipsychotics, which is effective in improving symptoms of manic episodes in patients with bipolar disorder, or schizoaffective disorder, bipolar type and has been shown to influence sleep in other psychiatric disorders. The present study evaluated the sleep effects of clozapine in bipolar and schizoaffective disorders.
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