{"result":[{"researchInterest":"We have six main areas of current interest: 1) Cranial Suture Developmental Biology, 2)Distraction Osteogenesis, 3) Cleft Palate and Lip Biology, 4)Keloid and Hypertrophic Scar Biology, 5) Scarless Fetal Wound Healing, 6) Novel Gene and Stem Cell Therapeutic Approaches.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4338&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Michael_Longaker","appointments":[{"appointment":"Professor,Surgery - Plastic/Recon Surgery"},{"appointment":"Professor (By courtesy),Bioengineering"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Plastic Surgery"},{"focus":"Plastic Surgery, Pediatric"}],"firstName":"Michael","primaryAppointment":"Professor,Surgery - Plastic/Recon Surgery","displayName":"Michael Longaker","lastName":"Longaker"},{"researchInterest":"The focus of my laboratory is to understand the role of hypoxia and the tumor microenvironment on malignant progression. My clinical area of interest is in the application of chemoradiotherapy and stereotactic radiosurgery for GI maligancies","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4729&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Albert_Koong","appointments":[{"appointment":"Assistant Professor,Radiation Oncology - Radiation Therapy"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Colorectal Cancer"},{"focus":"Colorectal Cancer - Radiation Oncology"},{"focus":"Esophageal Cancer"},{"focus":"Esophageal Cancer - Radiation Oncology"},{"focus":"Liver Cancer"},{"focus":"Liver Cancer - Radiation Oncology"},{"focus":"Pancreatic Cancer "},{"focus":"Pancreatic Cancer - Radiation Oncology"},{"focus":"Radiation Oncology"},{"focus":"Rectal Cancer "},{"focus":"Rectal Cancer - Radiation Oncology"},{"focus":"Stomach Cancer "},{"focus":"Stomach Cancer - Radiation Oncology"}],"firstName":"Albert","primaryAppointment":"Assistant Professor,Radiation Oncology - Radiation Therapy","displayName":"Albert Koong","lastName":"Koong"},{"researchInterest":"Application of Micro/Nanotechnology to Biological Systems.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4347&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Ralph_Greco","appointments":[{"appointment":"Professor,Surgery - General Surgery"},{"appointment":"Professor (By courtesy),Mechanical Engineering"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Carcinoid Tumors"},{"focus":"Carcinoid Tumors - Endocrinology"},{"focus":"Endocrine"},{"focus":"Endocrine - Surgery"},{"focus":"Endocrinology Surgery"},{"focus":"Gastrointestinal Cancers"},{"focus":"Gastrointestinal Cancers - Surgical Oncology"},{"focus":"General Surgery"},{"focus":"Osteosarcoma "},{"focus":"Osteosarcoma - Surgery"},{"focus":"Pancreas Surgery"},{"focus":"Pancreatic Cancer "},{"focus":"Pancreatic Cancer - Surgery"},{"focus":"Sarcomas - Surgical Oncology"}],"firstName":"Ralph","primaryAppointment":"Professor,Surgery - General Surgery","displayName":"Ralph S. Greco","lastName":"Greco"},{"researchInterest":"Cellular response to hypoxia and ionizing radiation; cell-cycle control, apoptosis and angiogenesis in transformed cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Amato_Giaccia","appointments":[{"appointment":"Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Amato","primaryAppointment":"Professor,Radiation Oncology - Radiation Biology","displayName":"Amato Giaccia","lastName":"Giaccia"},{"researchInterest":"We have three areas of current investigation: \r\n1) Scarless skin wound healing biology\r\n2) Dot stem cell tissue regeneration biology\r\n3) Novel stem cell therapy for tissue engineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4589&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Hermann_Lorenz","appointments":[{"appointment":"Professor - Med Center Line,Surgery - Plastic/Recon Surgery"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Plastic Surgery, Pediatric"},{"focus":"Plastic Surgery"},{"focus":"Cleft lip and palate surgery"},{"focus":"Facial surgery"},{"focus":"Plastic and Reconstructive Surgery"},{"focus":"facial fracture surgery"},{"focus":"Body contouring surgery"},{"focus":"abdominal wall surgery"},{"focus":"ventral hernia surgery"},{"focus":"incisional hernia surgery"}],"firstName":"Hermann","primaryAppointment":"Professor - Med Center Line,Surgery - Plastic/Recon Surgery","displayName":"H. Peter Lorenz, MD","lastName":"Lorenz"},{"researchInterest":"The Chang group is focused on two fundamental questions in epithelial biology: (1) the basis of positional identities in epidermal structures throughout the body, and (2) how those signals and boundaries may be abrogated to allow cancer metastasis. We are investigating the roles of site-specific fibroblast differentiation in patterning the epidermis, and dissecting the mechanisms of wound healing programs in cancer metastasis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6089&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Howard_Chang","appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Dermatology"}],"firstName":"Howard","primaryAppointment":"Associate Professor,Dermatology","displayName":"Howard Y. Chang","lastName":"Chang"},{"researchInterest":"Geoffrey Gurtner's Lab is interested in understanding the mecahnism of new blood vessel growth following injury and how pathways of tissue regeneration and fibrosis interact in wound healing.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6890&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Geoffrey_Gurtner","appointments":[{"appointment":"Professor - Med Center Line,Surgery - Plastic/Recon Surgery"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Plastic Surgery"}],"firstName":"Geoffrey","primaryAppointment":"Professor - Med Center Line,Surgery - Plastic/Recon Surgery","displayName":"Geoffrey Gurtner","lastName":"Gurtner"},{"researchInterest":"Understanding genetic basis of cardiovascular function and disease.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Thomas_Quertermous","appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"clinicalFocus":[],"firstName":"Thomas","primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","displayName":"Thomas Quertermous, MD","lastName":"Quertermous"},{"researchInterest":"Multimodality fusion imaging with PET, CT, and MRI for oncology.  \r\n\r\nTranslational research bringing new radiotracers to clinical use.\r\n\r\nCardiovascular multimodality PET/CT imaging.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6452&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Andrew_Quon","appointments":[{"appointment":"Assistant Professor - Med Center Line,Radiology - Nuclear Medicine"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Nuclear Medicine"}],"firstName":"Andrew","primaryAppointment":"Assistant Professor - Med Center Line,Radiology - Nuclear Medicine","displayName":"Andrew Quon","lastName":"Quon"},{"researchInterest":"Mammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNA\u000bdamage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4066&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/James_Ford","appointments":[{"appointment":"Associate Professor,Medicine - Oncology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Associate Professor (By courtesy),Pediatrics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Cancer Genetics"},{"focus":"Gastrointestinal Cancers - Genetics"},{"focus":"Gastrointestinal Cancers - Medical Oncology"},{"focus":"Breast Cancer - Genetics"},{"focus":"Ovarian Cancer - Genetics"},{"focus":"Medical Oncology"}],"firstName":"James","primaryAppointment":"Associate Professor,Medicine - Oncology","displayName":"James Ford","lastName":"Ford"},{"researchInterest":"Hedgehog signaling has been implicated in the induction or maintenance of up to 25% of human tumors and a variety of birth defects.  Our lab studies Sonic hedgehog (Shh) signaling in normal hair follicle development and in the pathogenesis of the most common human tumor, basal cell carcinoma (BCCs) of the skin.  We are interested in how the local stromal environment regulates hedgehog signaling and hair follicle or tumor growth and invasion.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4693&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Anthony_Oro","appointments":[{"appointment":"Associate Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[{"focus":"Dermatology"},{"focus":"Skin Cancer "},{"focus":"Hair disorders"}],"firstName":"Anthony","primaryAppointment":"Associate Professor,Dermatology","displayName":"Anthony Oro  MD/PhD","lastName":"Oro"},{"researchInterest":"Clinical expertise in GI cancers with research which emphasizes Phase I and II clinical trials of novel therapies but also includes translational studies including biomarkers, molecular imaging, tumor immunology and development of immunotherapeutic trials.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4644&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/George_Fisher","appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Oncology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"George","primaryAppointment":"Associate Professor - Med Center Line,Medicine - Oncology","displayName":"George A. Fisher Jr.","lastName":"Fisher"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4526&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Harry_Oberhelman","appointments":[{"appointment":"Emeritus (Active) Professor,Surgery - General Surgery"},{"appointment":"Emeritus Faculty, Acad Council,Surgery - General Surgery"}],"clinicalFocus":[{"focus":"General Surgery"}],"firstName":"Harry","primaryAppointment":"Emeritus (Active) Professor,Surgery - General Surgery","displayName":"Harry A. Oberhelman","lastName":"Oberhelman"},{"researchInterest":"Imaging of gastrointestinal tract cancer\r\nUltrasound\r\nSimulated learning environment","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4230&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Terry_Desser","appointments":[{"appointment":"Associate Professor - Med Center Line,Radiology - Diagnostic Radiology"}],"clinicalFocus":[{"focus":"Diagnostic Radiology"},{"focus":"Radiology"},{"focus":"Ultrasound"}],"firstName":"Terry","primaryAppointment":"Associate Professor - Med Center Line,Radiology - Diagnostic Radiology","displayName":"Terry Desser","lastName":"Desser"},{"researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Patrick_Brown","appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Patrick","primaryAppointment":"Professor,Biochemistry","displayName":"Patrick O. Brown","lastName":"Brown"},{"researchInterest":"My role in research is to apply novel advances in tissue engineering and microsurgery to the clinical problems of hand trauma, peripheral nerve injuries, and congenital hand problems.  I am interested in developing new tissues and techniques that will allow optimal reconstruction of form and function to those patients requiring reconstructive surgery.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4709&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/James_Chang","appointments":[{"appointment":"Professor - Med Center Line,Surgery - Plastic/Recon Surgery"},{"appointment":"Professor - Med Center Line (By courtesy),Orthopaedic Surgery"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Hand and Upper Extremity Surgery"},{"focus":"Plastic and Reconstructive Surgery"},{"focus":"Pediatric Hand Problems"},{"focus":"Peripheral Nerve Injuries"},{"focus":"Facial Nerve Injuries"},{"focus":"Plastic Surgery"},{"focus":"Hand Tumors"},{"focus":"Hand Arthritis"},{"focus":"Carpal Tunnel Syndrome"},{"focus":"Hand Scleroderma"},{"focus":"Microsurgery"},{"focus":"Complex Reconstruction"},{"focus":"Free Flap Reconstruction"},{"focus":"Lower Extremity Reconstruction"},{"focus":"Dupuytrens Disease"},{"focus":"Tendon Transfer"},{"focus":"Thumb Reconstruction"},{"focus":"Facial Paralysis"},{"focus":"Hand Fractures"},{"focus":"Microvascular Hand Surgery"},{"focus":"Hand Deformities"}],"firstName":"James","primaryAppointment":"Professor - Med Center Line,Surgery - Plastic/Recon Surgery","displayName":"James Chang","lastName":"Chang"},{"researchInterest":"We are interested in the biologic effect of gene expression changes that occur in the solid tumor.  Many of these expression changes are due to the micro-physiology within the tumor.  Several of these genes have been implicated in driving malignant progression and/or regulating response to therapeutic intervention.  We hope to use these molecular changes to develop novel targeted therapies that take advantage of tumor specific gene expression changes.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4577&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Nicholas_Denko","appointments":[{"appointment":"Assistant Professor,Radiation Oncology - Radiation Biology"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Nicholas","primaryAppointment":"Assistant Professor,Radiation Oncology - Radiation Biology","displayName":"Nicholas Denko","lastName":"Denko"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9355&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Deepak_Gupta","appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"clinicalFocus":[],"firstName":"Deepak","primaryAppointment":"Postdoctoral Research fellow, Surgery","displayName":"Deepak M. Gupta, MD","lastName":"Gupta"},{"researchInterest":"We work in epithelial tissue as a model system to study stem cell biology, cancer and new molecular therapeutics. Epithelia cover external and internal body surfaces and undergo constant self-renewal while responding to diverse environmental stimuli. Epithelial homeostasis precisely balances stem cell-sustained proliferation and differentiation-associated cell death, a balance which is lost in many human diseases, including cancer, 90% of which arise in epithelial tissues.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4683&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Paul_Khavari","appointments":[{"appointment":"Professor,Dermatology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Paul","primaryAppointment":"Professor,Dermatology","displayName":"Paul A. Khavari, MD, PhD","lastName":"Khavari"},{"researchInterest":"Applications of molecular imaging in radiation therapy, development of hypoxia and radiosensitivity imaging techniques, image processing and analysis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3974&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Edward_Graves","appointments":[{"appointment":"Assistant Professor,Radiation Oncology - Radiation Physics"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Edward","primaryAppointment":"Assistant Professor,Radiation Oncology - Radiation Physics","displayName":"Edward Graves","lastName":"Graves"},{"researchInterest":"Our laboratory uses genomics approaches to explore patterns of gene expression and gene copy number alteration in both human cancer cell line model systems and in tumors, with the goals of better understanding cancer, and developing novel diagnostic and therapeutic strategies.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6066&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Jonathan_Pollack","appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Jonathan","primaryAppointment":"Associate Professor,Pathology","displayName":"Jonathan Pollack","lastName":"Pollack"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9203&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Jonghyeob_Lee","appointments":[{"appointment":"Postdoctoral Research fellow, Developmental Biology"}],"clinicalFocus":[],"firstName":"Jonghyeob","primaryAppointment":"Postdoctoral Research fellow, Developmental Biology","displayName":"Jonghyeob Lee","lastName":"Lee"},{"researchInterest":"Dr. Helms' research interests center around craniofacial development and regenerative medicine.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6152&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Jill_Helms","appointments":[{"appointment":"Associate Professor,Surgery - Plastic/Recon Surgery"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Jill","primaryAppointment":"Associate Professor,Surgery - Plastic/Recon Surgery","displayName":"Jill Helms","lastName":"Helms"},{"researchInterest":"My lab focuses on cancer stem cell biology and its implications for cancer therapy. We are interested in developing a deeper molecular understanding of cancer stem cells, including identifying pathways and genes important for proliferation and self renewal. We also study these processes in normal adult stem cells in order to identify differences that could be exploited therapeutically. The goal of our studies is the development of novel therapeutic strategies for eliminating cancer stem cells.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9248&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Maximilian_Diehn","appointments":[{"appointment":"Acting Assistant Professor,Radiation Oncology - Radiation Therapy"}],"clinicalFocus":[],"firstName":"Maximilian","primaryAppointment":"Acting Assistant Professor,Radiation Oncology - Radiation Therapy","displayName":"Maximilian Diehn, M.D., Ph.D.","lastName":"Diehn"},{"researchInterest":"My research is in applied statistics and biostatistics. I specialize in \u000bcomputer-intensive methods for regression and classification, bootstrap, cross-validation\u000band statistical inference, and signal and image analysis for medical diagnosis.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4688&type=small&showNoImage","href":"http://med.stanford.edu/profiles/psrl/researcher/Robert_Tibshirani","appointments":[{"appointment":"Professor,Health Research & Policy - Biostatistics"},{"appointment":"Professor,Statistics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"Robert","primaryAppointment":"Professor,Health Research & Policy - Biostatistics","displayName":"Robert Tibshirani","lastName":"Tibshirani"}]}