Michael Longaker

Publications

• IFATS collection: Adipose stromal cells adopt a proangiogenic phenotype under the influence of hypoxia. Thangarajah H, Vial IN, Chang E, El-Ftesi S, Januszyk M, Chang EI, Paterno J, Neofytou E, Longaker MT, Gurtner GC. Stem Cells. 2009; 27 (1): 266-74
• Pulsed DC Electric Fields enhance osteogenesis in adipose-derived stromal cells. Hammerick KE, James AW, Huang Z, Prinz FB, Longaker M. Tissue Eng Part A. 2009
• Discussion. Yang GP, Longaker MT. Plast Reconstr Surg. 2009; 123 (1): 149-51
• Differential effects of TGF-beta1 and TGF-beta3 on chondrogenesis in posterofrontal cranial suture-derived mesenchymal cells in vitro. James AW, Xu Y, Lee JK, Wang R, Longaker MT. Plast Reconstr Surg. 2009; 123 (1): 31-43
• Cranial osteogenesis and suture morphology in Xenopus laevis: a unique model system for studying craniofacial development. Slater BJ, Liu KJ, Kwan MD, Quarto N, Longaker MT. PLoS One. 2009; 4 (1): e3914
• Discussion. Slater BJ, Kwan MD, Longaker MT. J Craniofac Surg. 2009; 20 (1): 176-177
• Aging and diabetes impair the neovascular potential of adipose-derived stromal cells. El-Ftesi S, Chang EI, Longaker MT, Gurtner GC. Plast Reconstr Surg. 2009; 123 (2): 475-85
• The role of regional posterior frontal dura mater in the overlying suture morphology. Slater BJ, Kwan MD, Gupta DM, Lee JK, Longaker MT. Plast Reconstr Surg. 2009; 123 (2): 463-9
• Differential FGF ligands and FGF receptors expression pattern in frontal and parietal calvarial bones. Quarto N, Behr B, Li S, Longaker MT. Cells Tissues Organs. 2009; 190 (3): 158-69
• Perspectives in cell-based skeletal tissue. Panetta NJ, Gupta DM, Longaker MT. J Craniofac Surg. 2009; 20 (2): 347-8
• Mesenchymal cells for skeletal tissue engineering. Panetta NJ, Gupta DM, Quarto N, Longaker MT. Panminerva Med. 2009; 51 (1): 25-41
• Ethnic diversity remains scarce in academic plastic and reconstructive surgery. Butler PD, Britt LD, Longaker MT. Plast Reconstr Surg. 2009; 123 (5): 1618-27
• The use of polymer scaffolds in skeletal tissue engineering applications. Gupta DM, Panetta NJ, Longaker MT. J Craniofac Surg. 2009; 20 (3): 860-1
• Tissue harvest by means of suction-assisted or third-generation ultrasound-assisted lipoaspiration has no effect on osteogenic potential of human adipose-derived stromal cells. Panetta NJ, Gupta DM, Kwan MD, Wan DC, Commons GW, Longaker MT. Plast Reconstr Surg. 2009; 124 (1): 65-73
• Ex vivo Model of Cranial Suture Morphogenesis and Fate. Slater BJ, Lenton KA, James A, Longaker MT. Cells Tissues Organs. 2009; 190 (6): 336-346
• Unfolded Protein Response Regulation in Keloid Cells. Butler PD, Wang Z, Ly DP, Longaker MT, Koong AC, Yang GP. J Surg Res. 2009
• Estrogen/estrogen receptor alpha signaling in mouse posterofrontal cranial suture fusion. James AW, Theologis AA, Brugmann SA, Xu Y, Carre AL, Leucht P, Hamilton K, Korach KS, Longaker MT. PLoS One. 2009; 4 (9): e7120
• Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells. Sun N, Panetta NJ, Gupta DM, Wilson KD, Lee A, Jia F, Hu S, Cherry AM, Robbins RC, Longaker MT, Wu JC. Proc Natl Acad Sci U S A. 2009; 106 (37): 15720-5
• Fetal skin wound healing. Buchanan EP, Longaker MT, Lorenz HP. Adv Clin Chem. 2009: 48 137-61
• Bone tissue engineering scaffolds of today and tomorrow. Panetta NJ, Gupta DM, Longaker MT. J Craniofac Surg. 2009; 20 (5): 1531-2
• Topical lineage-negative progenitor-cell therapy for diabetic wounds (invited discussion). Gurtner GC, Longaker MT. Plast Reconstr Surg. 2009; 123 (1): 421-3
• Increased rate of hair regrowth in mice with constitutive overexpression of Del1. Hsu GP, Mathy JA, Wang Z, Xia W, Sakamoto G, Kundu R, Longaker MT, Quertermous T, Yang GP. J Surg Res. 2008; 146 (1): 73-80
• Transforming growth factor-beta1 stimulates chondrogenic differentiation of posterofrontal suture-derived mesenchymal cells in vitro. Xu Y, James AW, Longaker MT. Plast Reconstr Surg. 2008; 122 (6): 1649-59
• Confocal laser scanning microscopic analysis of collagen scaffolding patterns in cranial sutures. Warren SM, Walder B, Dec W, Longaker MT, Ting K. J Craniofac Surg. 2008; 19 (1): 198-203
• Applications of an athymic nude mouse model of nonhealing critical-sized calvarial defects. Gupta DM, Kwan MD, Slater BJ, Wan DC, Longaker MT. J Craniofac Surg. 2008; 19 (1): 192-7
• Hydrostatic pressure enhances chondrogenic differentiation of human bone marrow stromal cells in osteochondrogenic medium. Wagner DR, Lindsey DP, Li KW, Tummala P, Chandran SE, Smith RL, Longaker MT, Carter DR, Beaupre GS. Ann Biomed Eng. 2008; 36 (5): 813-20
• Blood-derived small Dot cells reduce scar in wound healing. Kong W, Li S, Longaker MT, Lorenz HP. Exp Cell Res. 2008; 314 (7): 1529-39
• Tissue Engineering in Cleft Palate and Other Congenital Malformations. Panetta NJ, Gupta DM, Slater BJ, Kwan MD, Liu KJ, Longaker MT. Pediatr Res. 2008
• Cranial sutures: a brief review. Slater BJ, Lenton KA, Kwan MD, Gupta DM, Wan DC, Longaker MT. Plast Reconstr Surg. 2008; 121 (4): 170e-8e
• Current progress in keloid research and treatment. Butler PD, Longaker MT, Yang GP. J Am Coll Surg. 2008; 206 (4): 731-41
• Current treatment of craniosynostosis and future therapeutic directions. Wan DC, Kwan MD, Lorenz HP, Longaker MT. Front Oral Biol. 2008: 12 209-30
• Molecular mechanisms of FGF-2 inhibitory activity in the osteogenic context of mouse adipose-derived stem cells (mASCs). Quarto N, Wan DC, Longaker MT. Bone. 2008; 42 (6): 1040-52
• Tissue engineering in cleft palate and other congenital malformations. Panetta NJ, Gupta DM, Slater BJ, Kwan MD, Liu KJ, Longaker MT. Pediatr Res. 2008; 63 (5): 545-51
• Wound repair and regeneration. Gurtner GC, Werner S, Barrandon Y, Longaker MT. Nature. 2008; 453 (7193): 314-21
• Silva et al: Repair of cranial bone defects with calcium phosphate ceramic implant or autogenous bone graft. Amasha RR, Kwan MD, Longaker MT. J Craniofac Surg. 2008; 19 (3): 675-7
• Mesenchymal cells for skeletal tissue engineering. Slater BJ, Kwan MD, Gupta DM, Panetta NJ, Longaker MT. Expert Opin Biol Ther. 2008; 8 (7): 885-93
• Dissecting the influence of regional dura mater on cranial suture biology. Slater BJ, Kwan MD, Gupta DM, Amasha RR, Wan DC, Longaker MT. Plast Reconstr Surg. 2008; 122 (1): 77-84
• Proliferation, osteogenic differentiation, and fgf-2 modulation of posterofrontal/sagittal suture-derived mesenchymal cells in vitro. James AW, Xu Y, Wang R, Longaker MT. Plast Reconstr Surg. 2008; 122 (1): 53-63
• Fluid shear stress magnitude, duration, and total applied load regulate gene expression and nitric oxide production in primary calvarial osteoblast cultures. González O, Fong KD, Trindade MC, Warren SM, Longaker MT, Smith RL. Plast Reconstr Surg. 2008; 122 (2): 419-28
• Microarray analysis of the role of regional dura mater in cranial suture fate. Kwan MD, Wan DC, Wang Z, Gupta DM, Slater BJ, Longaker MT. Plast Reconstr Surg. 2008; 122 (2): 389-99
• Cell-based therapies for skeletal regenerative medicine. Kwan MD, Slater BJ, Wan DC, Longaker MT. Hum Mol Genet. 2008; 17 (R1): R93-8
• Regenerative medicine: the next frontier. Kwan MD, Longaker MT. Transplantation. 2008; 86 (2): 206-7
• Advances in science and technology: impact on craniofacial surgery. Kwan MD, Longaker MT. J Craniofac Surg. 2008; 19 (4): 1136-9
• Presidential address: leadership, teamwork, and SUS brand extension. Longaker MT, Surgery. 2008; 144 (2): 109-18
• Hepatic injury and the kinetics of bone marrow-derived hepatocyte transgene expression. Perryman SV, Jenkins DD, Streetz KL, Longaker MT, Sylvester KG. J Pediatr Surg. 2008; 43 (8): 1511-9
• Gene expression analysis of Dupuytren's disease: the role of TGF-beta2. Zhang AY, Fong KD, Pham H, Nacamuli RP, Longaker MT, Chang J. J Hand Surg Eur Vol. 2008; 33 (6): 783-90
• Differential expression of specific FGF ligands and receptor isoforms during osteogenic differentiation of mouse Adipose-derived Stem Cells (mASCs) recapitulates the in vivo osteogenic pattern. Quarto N, Longaker MT. Gene. 2008; 424 (1-2): 130-40
• Global age-dependent differences in gene expression in response to calvarial injury. Wan DC, Kwan MD, Gupta DM, Wang Z, Slater BJ, Panetta NJ, Morrell NT, Longaker MT. J Craniofac Surg. 2008; 19 (5): 1292-301
• Optimization of flexor tendon tissue engineering with a cyclic strain bioreactor. Riboh J, Chong AK, Pham H, Longaker M, Jacobs C, Chang J. J Hand Surg Am. 2008; 33 (8): 1388-96
• Major deficit in the number of underrepresented minority academic surgeons persists. Butler PD, Longaker MT, Britt LD. Ann Surg. 2008; 248 (5): 704-11
• Plastic surgery and the society of university surgeons: an expanding relationship. Longaker MT, Plast Reconstr Surg. 2008; 122 (5): 1581-2
• Use of organotypic coculture to study keloid biology. Butler PD, Ly DP, Longaker MT, Yang GP. Am J Surg. 2008; 195 (2): 144-8
• Live imaging of Smad2/3 signaling in mouse skin wound healing. Chong AK, Satterwhite T, Pham HM, Costa MA, Luo J, Longaker MT, Wyss-Coray T, Chang J. Wound Repair Regen. 2007 Sep-Oct; 15 (5): 762-6
• Hypertrophic scar formation following burns and trauma: new approaches to treatment. Aarabi S, Longaker MT, Gurtner GC. PLoS Med. 2007; 4 (9): e234
• Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice. Liu KJ, Arron JR, Stankunas K, Crabtree GR, Longaker MT. Nature. 2007; 446 (7131): 79-82
• Transforming growth factor-beta, Smad, and collagen expression patterns in fetal and adult keratinocytes. Colwell AS, Faudoa R, Krummel TM, Longaker MT, Lorenz HP. Plast Reconstr Surg. 2007; 119 (3): 852-7
• Isolation and characterization of posterofrontal/sagittal suture mesenchymal cells in vitro. Xu Y, Malladi P, Chiou M, Longaker MT. Plast Reconstr Surg. 2007; 119 (3): 819-29
• Keratinocytes modulate fetal and postnatal fibroblast transforming growth factor-beta and Smad expression in co-culture. Colwell AS, Yun R, Krummel TM, Longaker MT, Lorenz HP. Plast Reconstr Surg. 2007; 119 (5): 1440-5
• Re: differential effects of FGFR2 mutation in ophthalmologic findings in Apert syndrome. Kwan MD, Wan DC, Lorenz HP, Longaker MT. J Craniofac Surg. 2007; 18 (2): 459-60
• Analysis of the material properties of early chondrogenic differentiated adipose-derived stromal cells (ASC) using an in vitro three-dimensional micromass culture system. Xu Y, Balooch G, Chiou M, Bekerman E, Ritchie RO, Longaker MT. Biochem Biophys Res Commun. 2007; 359 (2): 311-6
• Hypoxia inducible factor-1alpha deficiency affects chondrogenesis of adipose-derived adult stromal cells. Malladi P, Xu Y, Chiou M, Giaccia AJ, Longaker MT. Tissue Eng. 2007; 13 (6): 1159-71
• Refining retinoic acid stimulation for osteogenic differentiation of murine adipose-derived adult stromal cells. Wan DC, Siedhoff MT, Kwan MD, Nacamuli RP, Wu BM, Longaker MT. Tissue Eng. 2007; 13 (7): 1623-31
• Mechanical load initiates hypertrophic scar formation through decreased cellular apoptosis. Aarabi S, Bhatt KA, Shi Y, Paterno J, Chang EI, Loh SA, Holmes JW, Longaker MT, Yee H, Gurtner GC. FASEB J. 2007; 21 (12): 3250-61
• Proposition 71 and CIRM--assessing the return on investment. Longaker MT, Baker LC, Greely HT. Nat Biotechnol. 2007; 25 (5): 513-21
• Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation. Wan DC, Pomerantz JH, Brunet LJ, Kim JB, Chou YF, Wu BM, Harland R, Blau HM, Longaker MT. J Biol Chem. 2007; 282 (36): 26450-9
• Accelerated bone repair after plasma laser corticotomies. Leucht P, Lam K, Kim JB, Mackanos MA, Simanovskii DM, Longaker MT, Contag CH, Schwettman HA, Helms JA. Ann Surg. 2007; 246 (1): 140-50
• In vitro analysis of transforming growth factor-beta1 inhibition in novel transgenic SBE-luciferase mice. Satterwhite TS, Chong AK, Luo J, Pham H, Costa M, Longaker MT, Wyss-Coray T, Chang J. Ann Plast Surg. 2007; 59 (2): 207-13
• In vitro expansion of adipose-derived adult stromal cells in hypoxia enhances early chondrogenesis. Xu Y, Malladi P, Chiou M, Bekerman E, Giaccia AJ, Longaker MT. Tissue Eng. 2007; 13 (12): 2981-93
• Dura mater-derived FGF-2 mediates mitogenic signaling in calvarial osteoblasts. Li S, Quarto N, Longaker MT. Am J Physiol Cell Physiol. 2007; 293 (6): C1834-42
• Increased CCN2 transcription in keloid fibroblasts requires cooperativity between AP-1 and SMAD binding sites. Xia W, Kong W, Wang Z, Phan TT, Lim IJ, Longaker MT, Yang GP. Ann Surg. 2007; 246 (5): 886-95
• Molecular and cellular characterization of mouse calvarial osteoblasts derived from neural crest and paraxial mesoderm. Xu Y, Malladi P, Zhou D, Longaker MT. Plast Reconstr Surg. 2007; 120 (7): 1783-95
• Cyclophilin C-associated protein is up-regulated during wound healing. Kong W, Li S, Longaker MT, Lorenz HP. J Cell Physiol. 2007; 210 (1): 153-60
• Progress and potential for regenerative medicine. Gurtner GC, Callaghan MJ, Longaker MT. Annu Rev Med. 2007: 58 299-312
• Novel techniques in hernia repair. Antony AK, Herrera FA, Easter DW, Longaker MT, Lorenz HP. Curr Surg. 2006 Sep-Oct; 63 (5): 306-9
• Skin wounds in the MRL/MPJ mouse heal with scar. Colwell AS, Krummel TM, Kong W, Longaker MT, Lorenz HP. Wound Repair Regen. 2006 Jan-Feb; 14 (1): 81-90
• Increased transcriptional response to mechanical strain in keloid fibroblasts due to increased focal adhesion complex formation. Wang Z, Fong KD, Phan TT, Lim IJ, Longaker MT, Yang GP. J Cell Physiol. 2006; 206 (2): 510-7
• Effect of reduced oxygen tension on chondrogenesis and osteogenesis in adipose-derived mesenchymal cells. Malladi P, Xu Y, Chiou M, Giaccia AJ, Longaker MT. Am J Physiol Cell Physiol. 2006; 290 (4): C1139-46
• Relationships between tissue dilatation and differentiation in distraction osteogenesis. Morgan EF, Longaker MT, Carter DR. Matrix Biol. 2006; 25 (2): 94-103
• Gene expression programs in response to hypoxia: cell type specificity and prognostic significance in human cancers. Chi JT, Wang Z, Nuyten DS, Rodriguez EH, Schaner ME, Salim A, Wang Y, Kristensen GB, Helland A, Børresen-Dale AL, Giaccia A, Longaker MT, Hastie T, Yang GP, van de Vijver MJ, Brown PO. PLoS Med. 2006; 3 (3): e47
• Expression of a novel gene, MafB, in Dupuytren's disease. Lee LC, Zhang AY, Chong AK, Pham H, Longaker MT, Chang J. J Hand Surg Am. 2006; 31 (2): 211-8
• P38 MAP kinase mediates transforming growth factor-beta2 transcription in human keloid fibroblasts. Xia W, Longaker MT, Yang GP. Am J Physiol Regul Integr Comp Physiol. 2006; 290 (3): R501-8
• Craniofacial bone tissue engineering. Wan DC, Nacamuli RP, Longaker MT. Dent Clin North Am. 2006; 50 (2): 175-90, vii
• Absence of the p53 tumor suppressor gene promotes osteogenesis in mesenchymal stem cells. Tataria M, Quarto N, Longaker MT, Sylvester KG. J Pediatr Surg. 2006; 41 (4): 624-32; discussion 624-32
• Differential transcriptional responses of keloid and normal keratinocytes to serum stimulation. Xia W, Phan TT, Lim IJ, Longaker MT, Yang GP. J Surg Res. 2006; 135 (1): 156-63
• Mitogenic and chondrogenic effects of fibroblast growth factor-2 in adipose-derived mesenchymal cells. Chiou M, Xu Y, Longaker MT. Biochem Biophys Res Commun. 2006; 343 (2): 644-52
• Guided tissue regeneration enhances bone formation in a rat model of failed osteogenesis. Fang TD, Nacamuli RP, Song HJ, Fong KD, Shi YY, Longaker MT. Plast Reconstr Surg. 2006; 117 (4): 1177-85
• The ISCFS: a body for clinical, educational, and research innovation. Longaker MT, Wan DC. J Craniofac Surg. 2006; 17 (2): 215-6
• Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis. Dornhöfer N, Spong S, Bennewith K, Salim A, Klaus S, Kambham N, Wong C, Kaper F, Sutphin P, Nacamuli R, Nacalumi R, Höckel M, Le Q, Longaker M, Yang G, Koong A, Giaccia A. Cancer Res. 2006; 66 (11): 5816-27
• Wnt-4 expression is increased in fibroblasts after TGF-beta1 stimulation and during fetal and postnatal wound repair. Colwell AS, Krummel TM, Longaker MT, Lorenz HP. Plast Reconstr Surg. 2006; 117 (7): 2297-301
• An in vivo mouse excisional wound model of scarless healing. Colwell AS, Krummel TM, Longaker MT, Lorenz HP. Plast Reconstr Surg. 2006; 117 (7): 2292-6
• Fetal and adult fibroblasts have similar TGF-beta-mediated, Smad-dependent signaling pathways. Colwell AS, Krummel TM, Longaker MT, Lorenz HP. Plast Reconstr Surg. 2006; 117 (7): 2277-83
• FGF-2 inhibits osteogenesis in mouse adipose tissue-derived stromal cells and sustains their proliferative and osteogenic potential state. Quarto N, Longaker MT. Tissue Eng. 2006; 12 (6): 1405-18
• Osteogenic differentiation of mouse adipose-derived adult stromal cells requires retinoic acid and bone morphogenetic protein receptor type IB signaling. Wan DC, Shi YY, Nacamuli RP, Quarto N, Lyons KM, Longaker MT. Proc Natl Acad Sci U S A. 2006; 103 (33): 12335-40
• Functions of vitamin D, retinoic acid, and dexamethasone in mouse adipose-derived mesenchymal cells. Malladi P, Xu Y, Yang GP, Longaker MT. Tissue Eng. 2006; 12 (7): 2031-40
• Differential gene expression between juvenile and adult dura mater: a window into what genes play a role in the regeneration of membranous bone. Wan DC, Aalami OO, Wang Z, Nacamuli RP, Lorget F, Derynck R, Longaker MT. Plast Reconstr Surg. 2006; 118 (4): 851-61
• Epithelial-mesenchymal transition occurs after epidermal development in mouse skin. Kong W, Li S, Liu C, Bari AS, Longaker MT, Lorenz HP. Exp Cell Res. 2006; 312 (19): 3959-68
• Early-gestation fetal scarless wounds have less lysyl oxidase expression. Colwell AS, Krummel TM, Longaker MT, Lorenz HP. Plast Reconstr Surg. 2006; 118 (5): 1125-9; discussion 1130-1
• Innovation in surgery: a historical perspective. Riskin DJ, Longaker MT, Gertner M, Krummel TM. Ann Surg. 2006; 244 (5): 686-93
• The ethics of innovation in pediatric surgery. Riskin DJ, Longaker MT, Krummel TM. Semin Pediatr Surg. 2006; 15 (4): 319-23
• Mannose-6-phosphate, an inhibitor of transforming growth factor-beta, improves range of motion after flexor tendon repair. Bates SJ, Morrow E, Zhang AY, Pham H, Longaker MT, Chang J. J Bone Joint Surg Am. 2006; 88 (11): 2465-72
• Bone morphogenetic protein 2 and retinoic acid accelerate in vivo bone formation, osteoclast recruitment, and bone turnover. Cowan CM, Aalami OO, Shi YY, Chou YF, Mari C, Thomas R, Quarto N, Nacamuli RP, Contag CH, Wu B, Longaker MT. Tissue Eng. 2005 Mar-Apr; 11 (3-4): 645-58
• Angiogenesis is required for successful bone induction during distraction osteogenesis. Fang TD, Salim A, Xia W, Nacamuli RP, Guccione S, Song HM, Carano RA, Filvaroff EH, Bednarski MD, Giaccia AJ, Longaker MT. J Bone Miner Res. 2005; 20 (7): 1114-24
• Gene profiling of cells expressing different FGF-2 forms. Quarto N, Fong KD, Longaker MT. Gene. 2005: 356 49-68
• Adipose-derived mesenchymal cells as a potential cell source for skeletal regeneration. Xu Y, Malladi P, Wagner DR, Longaker MT. Curr Opin Mol Ther. 2005; 7 (4): 300-5
• Age-dependent properties and quasi-static strain in the rat sagittal suture. Henderson JH, Chang LY, Song HM, Longaker MT, Carter DR. J Biomech. 2005; 38 (11): 2294-301
• Microarray analysis of mechanical shear effects on flexor tendon cells. Fong KD, Trindade MC, Wang Z, Nacamuli RP, Pham H, Fang TD, Song HM, Smith RL, Longaker MT, Chang J. Plast Reconstr Surg. 2005; 116 (5): 1393-404; discussion 1405-6
• Hypertrophic scar fibroblasts have increased connective tissue growth factor expression after transforming growth factor-beta stimulation. Colwell AS, Phan TT, Kong W, Longaker MT, Lorenz PH. Plast Reconstr Surg. 2005; 116 (5): 1387-90; discussion 1391-2
• Expression and possible mechanisms of regulation of BMP3 in rat cranial sutures. Nacamuli RP, Fong KD, Lenton KA, Song HM, Fang TD, Salim A, Longaker MT. Plast Reconstr Surg. 2005; 116 (5): 1353-62
• Bone induction in craniofacial defects. Nacamuli RP, Longaker MT. Orthod Craniofac Res. 2005; 8 (4): 259-66
• The osteogenic potential of adipose-derived mesenchymal cells is maintained with aging. Shi YY, Nacamuli RP, Salim A, Longaker MT. Plast Reconstr Surg. 2005; 116 (6): 1686-96
• The zebrafish (Danio rerio): a model system for cranial suture patterning. Quarto N, Longaker MT. Cells Tissues Organs. 2005; 181 (2): 109-18
• Age-dependent residual tensile strains are present in the dura mater of rats. Henderson JH, Nacamuli RP, Zhao B, Longaker MT, Carter DR. J R Soc Interface. 2005; 2 (3): 159-67
• High-dose retinoic acid modulates rat calvarial osteoblast biology. Song HM, Nacamuli RP, Xia W, Bari AS, Shi YY, Fang TD, Longaker MT. J Cell Physiol. 2005; 202 (1): 255-62
• Mechanobiology of mandibular distraction osteogenesis: finite element analyses with a rat model. Loboa EG, Fang TD, Parker DW, Warren SM, Fong KD, Longaker MT, Carter DR. J Orthop Res. 2005; 23 (3): 663-70
• Sox9 neural crest determinant gene controls patterning and closure of the posterior frontal cranial suture. Sahar DE, Longaker MT, Quarto N. Dev Biol. 2005; 280 (2): 344-61
• Increased angiogenesis and expression of vascular endothelial growth factor during scarless repair. Colwell AS, Beanes SR, Soo C, Dang C, Ting K, Longaker MT, Atkinson JB, Lorenz HP. Plast Reconstr Surg. 2005; 115 (1): 204-12
• Differential transcriptional expression profiles of juvenile and adult calvarial bone. Aalami OO, Nacamuli RP, Salim A, Fong KD, Lenton KA, Song HM, Fang TD, Longaker MT. Plast Reconstr Surg. 2005; 115 (7): 1986-94
• Cranial suture biology. Lenton KA, Nacamuli RP, Wan DC, Helms JA, Longaker MT. Curr Top Dev Biol. 2005: 66 287-328
• Mammalian fetal organ regeneration. Colwell AS, Longaker MT, Lorenz HP. Adv Biochem Eng Biotechnol. 2005: 93 83-100
• FGF-2 acts through an ERK1/2 intracellular pathway to affect osteoblast differentiation. Spector JA, Mathy JA, Warren SM, Nacamuli RP, Song HM, Lenton K, Fong KD, Fang DT, Longaker MT. Plast Reconstr Surg. 2005; 115 (3): 838-52
• New developments in pediatric plastic surgery research. Nacamuli RP, Wan DC, Lenton KA, Longaker MT. Clin Plast Surg. 2005; 32 (1): 123-36, ix-x
• Complex epithelial-mesenchymal interactions modulate transforming growth factor-beta expression in keloid-derived cells. Xia W, Phan TT, Lim IJ, Longaker MT, Yang GP. Wound Repair Regen. 2004 Sep-Oct; 12 (5): 546-56
• Cyclophilin C-associated protein is a mediator for fibronectin fragment-induced matrix metalloproteinase-13 expression. Kong W, Longaker MT, Lorenz HP. J Biol Chem. 2004; 279 (53): 55334-40
• Donor-derived, liver-specific protein expression after bone marrow transplantation. Jenkins DD, Streetz K, Tataria M, Sahar D, Kurobe M, Longaker MT, Kay MA, Sylvester KG. Transplantation. 2004; 78 (4): 530-6
• Applications of a mouse model of calvarial healing: differences in regenerative abilities of juveniles and adults. Aalami OO, Nacamuli RP, Lenton KA, Cowan CM, Fang TD, Fong KD, Shi YY, Song HM, Sahar DE, Longaker MT. Plast Reconstr Surg. 2004; 114 (3): 713-20
• Transient changes in oxygen tension inhibit osteogenic differentiation and Runx2 expression in osteoblasts. Salim A, Nacamuli RP, Morgan EF, Giaccia AJ, Longaker MT. J Biol Chem. 2004; 279 (38): 40007-16
• Apoptosis in a rodent model of cranial suture fusion: in situ imaging and gene expression analysis. Fong KD, Song HM, Nacamuli RP, Franc BL, Mari C, Fang TD, Warren SM, Contag CH, Blankenberg FG, Longaker MT. Plast Reconstr Surg. 2004; 113 (7): 2037-47
• Creation and characterization of a mouse model of mandibular distraction osteogenesis. Fang TD, Nacamuli RP, Song HM, Fong KD, Warren SM, Salim A, Carano RA, Filvaroff EH, Longaker MT. Bone. 2004; 34 (6): 1004-12
• Mechanisms of murine cranial suture patency mediated by a dominant negative transforming growth factor-beta receptor adenovirus. Song HM, Fong KD, Nacamuli RP, Warren SM, Fang TD, Mathy JA, Cowan CM, Aalami OO, Longaker MT. Plast Reconstr Surg. 2004; 113 (6): 1685-97
• Highlights of the proceedings from the 10th International Congress of the International Society of Craniofacial Surgery. Lorenz HP, Longaker MT. J Craniofac Surg. 2004; 15 (3): 533-7
• In vitro murine posterior frontal suture fate is age-dependent: implications for cranial suture biology. Song HM, Sahar DE, Fong KD, Nacamuli RP, Fang TD, Mathy JA, Aalami OO, Warren SM, Longaker MT. Plast Reconstr Surg. 2004; 113 (4): 1192-204
• Adipose-derived adult stromal cells heal critical-size mouse calvarial defects. Cowan CM, Shi YY, Aalami OO, Chou YF, Mari C, Thomas R, Quarto N, Contag CH, Wu B, Longaker MT. Nat Biotechnol. 2004; 22 (5): 560-7
• Inhibition of TGF-beta-induced collagen production in rabbit flexor tendons. Zhang AY, Pham H, Ho F, Teng K, Longaker MT, Chang J. J Hand Surg Am. 2004; 29 (2): 230-5
• Mechanobiology of mandibular distraction osteogenesis: experimental analyses with a rat model. Loboa EG, Fang TD, Warren SM, Lindsey DP, Fong KD, Longaker MT, Carter DR. Bone. 2004; 34 (2): 336-43
• Sutural bone deposition rate and strain magnitude during cranial development. Henderson JH, Longaker MT, Carter DR. Bone. 2004; 34 (2): 271-80
• Flexor tendon wound healing in vitro: lactate up-regulation of TGF-beta expression and functional activity. Yalamanchi N, Klein MB, Pham HM, Longaker MT, Chang J. Plast Reconstr Surg. 2004; 113 (2): 625-32
• Stem cells: review and update. Sylvester KG, Longaker MT. Arch Surg. 2004; 139 (1): 93-9
• Tissue-engineered bone using mesenchymal stem cells and a biodegradable scaffold. Warren SM, Nacamuli RK, Song HM, Longaker MT. J Craniofac Surg. 2004; 15 (1): 34-7
• Quantitative transcriptional analysis of fusing and nonfusing cranial suture complexes in mice. Nacamuli RP, Song HM, Fang TD, Fong KD, Mathy JA, Shi YY, Salim A, Longaker MT. Plast Reconstr Surg. 2004; 114 (7): 1818-25
• From scarless fetal wounds to keloids: molecular studies in wound healing. Yang GP, Lim IJ, Phan TT, Lorenz HP, Longaker MT. Wound Repair Regen. 2003 Nov-Dec; 11 (6): 411-8
• Tissue engineering and regenerative medicine. Jenkins DD, Yang GP, Lorenz HP, Longaker MT, Sylvester KG. Clin Plast Surg. 2003; 30 (4): 581-8
• Molecular cloning and expression of keratinocyte proline-rich protein, a novel squamous epithelial marker isolated during skin development. Kong W, Longaker MT, Lorenz HP. J Biol Chem. 2003; 278 (25): 22781-6
• Mechanical strain affects dura mater biological processes: implications for immature calvarial healing. Fong KD, Warren SM, Loboa EG, Henderson JH, Fang TD, Cowan CM, Carter DR, Longaker MT. Plast Reconstr Surg. 2003; 112 (5): 1312-27
• Porous polymethylmethacrylate as bone substitute in the craniofacial area. Bruens ML, Pieterman H, de Wijn JR, et al. J Craniofac Surg 2003; 14:63-68. Lenton KA, Nacamuli RP, Longaker MT. J Craniofac Surg. 2003; 14 (4): 596-8
• The influence of temperature on the degradation rate of LactoSorb Copolymer. Pietrzak WS, Kumar M, Eppley BL. J Craniofac Surg 2003; 14:176-183. Fong KD, Nacamuli RP, Longaker MT. J Craniofac Surg. 2003; 14 (4): 594-5
• The BMP antagonist noggin regulates cranial suture fusion. Warren SM, Brunet LJ, Harland RM, Economides AN, Longaker MT. Nature. 2003; 422 (6932): 625-9
• In utero surgery for cleft lip/palate: minimizing the "Ripple Effect" of scarring. Lorenz HP, Longaker MT. J Craniofac Surg. 2003; 14 (4): 504-11
• Regional dura mater differentially regulates osteoblast gene expression. Warren SM, Greenwald JA, Nacamuli RP, Fong KD, Song HJ, Fang TD, Mathy JA, Longaker MT. J Craniofac Surg. 2003; 14 (3): 363-70
• Equibiaxial tensile strain affects calvarial osteoblast biology. Fong KD, Nacamuli RP, Loboa EG, Henderson JH, Fang TD, Song HM, Cowan CM, Warren SM, Carter DR, Longaker MT. J Craniofac Surg. 2003; 14 (3): 348-55
• New strategies for craniofacial repair and replacement: a brief review. Fong KD, Nacamuli RP, Song HM, Warren SM, Lorenz HP, Longaker MT. J Craniofac Surg. 2003; 14 (3): 333-9
• Methods for investigating fetal tissue repair. Peled ZM, Warren SM, Bouletreau PJ, Longaker MT. Methods Mol Med. 2003: 78 149-59
• Age-related changes in the biomolecular mechanisms of calvarial osteoblast biology affect fibroblast growth factor-2 signaling and osteogenesis. Cowan CM, Quarto N, Warren SM, Salim A, Longaker MT. J Biol Chem. 2003; 278 (34): 32005-13
• Tools and techniques for craniofacial tissue engineering. Warren SM, Fong KD, Chen CM, Loboa EG, Cowan CM, Lorenz HP, Longaker MT. Tissue Eng. 2003; 9 (2): 187-200
• Markers of osteoblast differentiation in fusing and nonfusing cranial sutures. Nacamuli RP, Fong KD, Warren SM, Fang TD, Song HM, Helms JA, Longaker MT. Plast Reconstr Surg. 2003; 112 (5): 1328-35
• FGF-2 stimulation affects calvarial osteoblast biology: quantitative analysis of nine genes important for cranial suture biology by real-time reverse transcription polymerase chain reaction. Mathy JA, Lenton K, Nacamuli RP, Fong KD, Song HM, Fang TD, Yang GP, Longaker MT. Plast Reconstr Surg. 2003; 112 (2): 528-39
• Flexor tendon healing in vitro: effects of TGF-beta on tendon cell collagen production. Klein MB, Yalamanchi N, Pham H, Longaker MT, Chang J. J Hand Surg Am. 2002; 27 (4): 615-20
• Re: Sequence analysis of fibroblast growth factor receptor 2 (FGFR2) in Japanese patients with craniosynostosis. Sakai et al. J Craniofac. Surg. 2001, 12: 580-585. Warren SM, Longaker MT. J Craniofac Surg. 2002; 13 (4): 597-9
• Matrix metalloproteinases and the ontogeny of scarless repair: the other side of the wound healing balance. Peled ZM, Phelps ED, Updike DL, Chang J, Krummel TM, Howard EW, Longaker MT. Plast Reconstr Surg. 2002; 110 (3): 801-11
• Overhealing, underhealing, and skin regeneration: a new perspective on wound healing. Peled ZM, Galiano R, Chin GS, Chang J, Krummel TM, Longaker MT. Asian J Surg. 2002; 25 (1): 102-10
• Factors in the fracture microenvironment induce primary osteoblast angiogenic cytokine production. Bouletreau PJ, Warren SM, Spector JA, Steinbrech DS, Mehrara BJ, Longaker MT. Plast Reconstr Surg. 2002; 110 (1): 139-48
• Co-culture of osteoblasts with immature dural cells causes an increased rate and degree of osteoblast differentiation. Spector JA, Greenwald JA, Warren SM, Bouletreau PJ, Crisera FE, Mehrara BJ, Longaker MT. Plast Reconstr Surg. 2002; 109 (2): 631-42; discussion 643-4
• Hypoxia and VEGF up-regulate BMP-2 mRNA and protein expression in microvascular endothelial cells: implications for fracture healing. Bouletreau PJ, Warren SM, Spector JA, Peled ZM, Gerrets RP, Greenwald JA, Longaker MT. Plast Reconstr Surg. 2002; 109 (7): 2384-97
• The pathogenesis of craniosynostosis in the fetus. Warren SM, Longaker MT. Yonsei Med J. 2001; 42 (6): 646-59
• In vivo modulation of FGF biological activity alters cranial suture fate. Greenwald JA, Mehrara BJ, Spector JA, Warren SM, Fagenholz PJ, Smith LE, Bouletreau PJ, Crisera FE, Ueno H, Longaker MT. Am J Pathol. 2001; 158 (2): 441-52
• Gene expression of transforming growth factor beta isoforms in interposition nerve grafting. Karanas YL, Bogdan MA, Lineaweaver WC, Hentz VR, Longaker MT, Chang J. J Hand Surg Am. 2001; 26 (6): 1082-7
• Fetal wound healing: progress report and future directions. Longaker MT, Peled ZM, Chang J, Krummel TM. Surgery. 2001; 130 (5): 785-7
• Differential expression of transforming growth factor-beta receptors in a rabbit zone II flexor tendon wound healing model. Ngo M, Pham H, Longaker MT, Chang J. Plast Reconstr Surg. 2001; 108 (5): 1260-7
• The ontogeny of scarless healing II: EGF and PDGF-B gene expression in fetal rat skin and fibroblasts as a function of gestational age. Peled ZM, Rhee SJ, Hsu M, Chang J, Krummel TM, Longaker MT. Ann Plast Surg. 2001; 47 (4): 417-24
• Differential expression of transforming growth factor-beta receptors I and II and activation of Smad 3 in keloid fibroblasts. Chin GS, Liu W, Peled Z, Lee TY, Steinbrech DS, Hsu M, Longaker MT. Plast Reconstr Surg. 2001; 108 (2): 423-9
• Role of TGF-beta signaling in the regulation of programmed cranial suture fusion. Longaker MT, J Craniofac Surg. 2001; 12 (4): 389-90
• Ontogeny of expression of transforming growth factor-beta 1 (TGF-beta 1), TGF-beta 3, and TGF-beta receptors I and II in fetal rat fibroblasts and skin. Hsu M, Peled ZM, Chin GS, Liu W, Longaker MT. Plast Reconstr Surg. 2001; 107 (7): 1787-94; discussion 1795-6
• Discoidin domain receptors and their ligand, collagen, are temporally regulated in fetal rat fibroblasts in vitro. Chin GS, Lee S, Hsu M, Liu W, Kim WJ, Levinson H, Longaker MT. Plast Reconstr Surg. 2001; 107 (3): 769-76
• New developments in cranial suture research. Warren SM, Greenwald JA, Spector JA, Bouletreau P, Mehrara BJ, Longaker MT. Plast Reconstr Surg. 2001; 107 (2): 523-40
• Rat mandibular distraction osteogenesis: part III. Gradual distraction versus acute lengthening. Warren SM, Mehrara BJ, Steinbrech DS, Paccione MF, Greenwald JA, Spector JA, Longaker MT. Plast Reconstr Surg. 2001; 107 (2): 441-53
• New directions in plastic surgery research. Warren SM, Longaker MT. Clin Plast Surg. 2001; 28 (4): 719-30
• The impact of biomolecular medicine and tissue engineering on plastic surgery in the 21st century. Lorenz HP, Hedrick MH, Chang J, Mehrara BJ, Longaker MT. Plast Reconstr Surg. 2000; 105 (7): 2467-81
• VEGF expression in an osteoblast-like cell line is regulated by a hypoxia response mechanism. Steinbrech DS, Mehrara BJ, Saadeh PB, Greenwald JA, Spector JA, Gittes GK, Longaker MT. Am J Physiol Cell Physiol. 2000; 278 (4): C853-60
• A molecular analysis of the isolated rat posterior frontal and sagittal sutures: differences in gene expression. Spector JA, Mehrara BJ, Greenwald JA, Saadeh PB, Steinbrech DS, Smith LP, Longaker MT. Plast Reconstr Surg. 2000; 106 (4): 852-61; discussion 862-7
• Mechanisms of fibroblast growth factor-2 modulation of vascular endothelial growth factor expression by osteoblastic cells. Saadeh PB, Mehrara BJ, Steinbrech DS, Spector JA, Greenwald JA, Chin GS, Ueno H, Gittes GK, Longaker MT. Endocrinology. 2000; 141 (6): 2075-83
• Studies in flexor tendon wound healing: neutralizing antibody to TGF-beta1 increases postoperative range of motion. Chang J, Thunder R, Most D, Longaker MT, Lineaweaver WC. Plast Reconstr Surg. 2000; 105 (1): 148-55
• Proliferative hemangiomas: analysis of cytokine gene expression and angiogenesis. Chang J, Most D, Bresnick S, Mehrara B, Steinbrech DS, Reinisch J, Longaker MT, Turk AE. Plast Reconstr Surg. 1999; 103 (1): 1-9; discussion 10
• Molecular studies in flexor tendon wound healing: the role of basic fibroblast growth factor gene expression. Chang J, Most D, Thunder R, Mehrara B, Longaker MT, Lineaweaver WC. J Hand Surg Am. 1998; 23 (6): 1052-8
• Gene expression of transforming growth factor beta-1 in rabbit zone II flexor tendon wound healing: evidence for dual mechanisms of repair. Chang J, Most D, Stelnicki E, Siebert JW, Longaker MT, Hui K, Lineaweaver WC. Plast Reconstr Surg. 1997; 100 (4): 937-44