Garry Nolan

Publications

• Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Kotecha N, Flores NJ, Irish JM, Simonds EF, Sakai DS, Archambeault S, Diaz-Flores E, Coram M, Shannon KM, Nolan GP, Loh ML. Cancer Cell. 2008; 14 (4): 335-43
• What's wrong with drug screening today. Nolan GP, Nat Chem Biol. 2007; 3 (4): 187-91
• Transcending the biomarker mindset: deciphering disease mechanisms at the single cell level. Danna EA, Nolan GP. Curr Opin Chem Biol. 2006; 10 (1): 20-7
• Mapping normal and cancer cell signalling networks: towards single-cell proteomics. Irish JM, Kotecha N, Nolan GP. Nat Rev Cancer. 2006; 6 (2): 146-55
• Causal protein-signaling networks derived from multiparameter single-cell data. Sachs K, Perez O, Pe'er D, Lauffenburger DA, Nolan GP. Science. 2005; 308 (5721): 523-9
• LFA-1 signaling through p44/42 is coupled to perforin degranulation in CD56+CD8+ natural killer cells. Perez OD, Mitchell D, Jager GC, Nolan GP. Blood. 2004; 104 (4): 1083-93
• In vivo targeting of organic calcium sensors via genetically selected peptides. Marks KM, Rosinov M, Nolan GP. Chem Biol. 2004; 11 (3): 347-56
• Single cell profiling of potentiated phospho-protein networks in cancer cells. Irish JM, Hovland R, Krutzik PO, Perez OD, Bruserud Ø, Gjertsen BT, Nolan GP. Cell. 2004; 118 (2): 217-28
• A general approach for chemical labeling and rapid, spatially controlled protein inactivation. Marks KM, Braun PD, Nolan GP. Proc Natl Acad Sci U S A. 2004; 101 (27): 9982-7
• Induction of anti-tumor immunity in mice using a syngeneic endothelial cell vaccine. Scappaticci FA, Nolan GP. Anticancer Res. 2003 Mar-Apr; 23 (2B): 1165-72
• Leukocyte functional antigen 1 lowers T cell activation thresholds and signaling through cytohesin-1 and Jun-activating binding protein 1. Perez OD, Mitchell D, Jager GC, South S, Murriel C, McBride J, Herzenberg LA, Kinoshita S, Nolan GP. Nat Immunol. 2003; 4 (11): 1083-92
• Intracellular phospho-protein staining techniques for flow cytometry: monitoring single cell signaling events. Krutzik PO, Nolan GP. Cytometry A. 2003; 55 (2): 61-70
• Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry. Perez OD, Nolan GP. Nat Biotechnol. 2002; 20 (2): 155-62
• Activation of the PKB/AKT pathway by ICAM-2. Perez OD, Kinoshita S, Hitoshi Y, Payan DG, Kitamura T, Nolan GP, Lorens JB. Immunity. 2002; 16 (1): 51-65
• Resistance is futile: assimilation of cellular machinery by HIV-1. Perez OD, Nolan GP. Immunity. 2001; 15 (5): 687-90
• Dominant effector genetics in mammalian cells. Xu X, Leo C, Jang Y, Chan E, Padilla D, Huang BC, Lin T, Gururaja T, Hitoshi Y, Lorens JB, Anderson DC, Sikic B, Luo Y, Payan DG, Nolan GP. Nat Genet. 2001; 27 (1): 23-9
• Retroviral delivery of peptide modulators of cellular functions. Lorens JB, Bennett MK, Pearsall DM, Throndset WR, Rossi AB, Armstrong RJ, Fox BP, Chan EH, Luo Y, Masuda E, Ferrick DA, Anderson DC, Payan DG, Nolan GP. Mol Ther. 2000; 1 (5 Pt 1): 438-47
• Evolution of peptides that modulate the spectral qualities of bound, small-molecule fluorophores. Rozinov MN, Nolan GP. Chem Biol. 1998; 5 (12): 713-28
• Host control of HIV-1 parasitism in T cells by the nuclear factor of activated T cells. Kinoshita S, Chen BK, Kaneshima H, Nolan GP. Cell. 1998; 95 (5): 595-604
• Cardiac development. Transcription and the broken heart. Nolan GP, Nature. 1998; 392 (6672): 129-30
• The T cell activation factor NF-ATc positively regulates HIV-1 replication and gene expression in T cells. Kinoshita S, Su L, Amano M, Timmerman LA, Kaneshima H, Nolan GP. Immunity. 1997; 6 (3): 235-44
• Harnessing viral devices as pharmaceuticals: fighting HIV-1's fire with fire. Nolan GP, Cell. 1997; 90 (5): 821-4
• Episomal vectors rapidly and stably produce high-titer recombinant retrovirus. Kinsella TM, Nolan GP. Hum Gene Ther. 1996; 7 (12): 1405-13
• NF-AT components define a family of transcription factors targeted in T-cell activation. Northrop JP, Ho SN, Chen L, Thomas DJ, Timmerman LA, Nolan GP, Admon A, Crabtree GR. Nature. 1994; 369 (6480): 497-502
• NF-AT-AP-1 and Rel-bZIP: hybrid vigor and binding under the influence. Nolan GP, Cell. 1994; 77 (6): 795-8
• Production of high-titer helper-free retroviruses by transient transfection. Pear WS, Nolan GP, Scott ML, Baltimore D. Proc Natl Acad Sci U S A. 1993; 90 (18): 8392-6
• The inhibitory ankyrin and activator Rel proteins. Nolan GP, Baltimore D. Curr Opin Genet Dev. 1992; 2 (2): 211-20
• DNA binding and I kappa B inhibition of the cloned p65 subunit of NF-kappa B, a rel-related polypeptide. Nolan GP, Ghosh S, Liou HC, Tempst P, Baltimore D. Cell. 1991; 64 (5): 961-9
• Whole animal cell sorting of Drosophila embryos. Krasnow MA, Cumberledge S, Manning G, Herzenberg LA, Nolan GP. Science. 1991; 251 (4989): 81-5
• Cloning of the p50 DNA binding subunit of NF-kappa B: homology to rel and dorsal. Ghosh S, Gifford AM, Riviere LR, Tempst P, Nolan GP, Baltimore D. Cell. 1990; 62 (5): 1019-29
• Fluorescence-activated cell analysis and sorting of viable mammalian cells based on beta-D-galactosidase activity after transduction of Escherichia coli lacZ. Nolan GP, Fiering S, Nicolas JF, Herzenberg LA. Proc Natl Acad Sci U S A. 1988; 85 (8): 2603-7
• WebFlow: a software package for high-throughput analysis of flow cytometry data. Hammer MM, Kotecha N, Irish JM, Nolan GP, Krutzik PO. Assay Drug Dev Technol. 2009; 7 (1): 44-55
• Learning signaling network structures with sparsely distributed data. Sachs K, Itani S, Carlisle J, Nolan GP, Pe'er D, Lauffenburger DA. J Comput Biol. 2009; 16 (2): 201-12
• Conditional protein stabilization via the small molecules Shld-1 and rapamycin increases the signal-to-noise ratio with tet-inducible gene expression. Almogy G, Nolan GP. Biotechniques. 2009; 46 (1): 44-50
• A novel method for detection of phosphorylation in single cells by surface enhanced Raman scattering (SERS) using composite organic-inorganic nanoparticles (COINs). Shachaf CM, Elchuri SV, Koh AL, Zhu J, Nguyen LN, Mitchell DJ, Zhang J, Swartz KB, Sun L, Chan S, Sinclair R, Nolan GP. PLoS One. 2009; 4 (4): e5206
• The initial phase of an immune response functions to activate regulatory T cells. O'Gorman WE, Dooms H, Thorne SH, Kuswanto WF, Simonds EF, Krutzik PO, Nolan GP, Abbas AK. J Immunol. 2009; 183 (1): 332-9
• The T cell STAT signaling network is reprogrammed within hours of bacteremia via secondary signals. Hotson AN, Hardy JW, Hale MB, Contag CH, Nolan GP. J Immunol. 2009; 182 (12): 7558-68
• High-content single-cell drug screening with phosphospecific flow cytometry. Krutzik PO, Crane JM, Clutter MR, Nolan GP. Nat Chem Biol. 2008; 4 (2): 132-42
• Single-cell, phosphoepitope-specific analysis demonstrates cell type- and pathway-specific dysregulation of Jak/STAT and MAPK signaling associated with in vivo human immunodeficiency virus type 1 infection. Lee AW, Sharp ER, O'Mahony A, Rosenberg MG, Israelski DM, Nolan GP, Nixon DF. J Virol. 2008; 82 (7): 3702-12
• Electron Microscopy Characterization of Composite Organic-Inorganic Nanoparticles (COINs) as Raman Labels for Extra-cellular Analyses. Koh A, Shachaf C, Elchuri S, Nolan G, Sinclair R. Microsc Microanal. 2008: 14 Suppl 2 670-1
• Electron microscopy localization and characterization of functionalized composite organic-inorganic SERS nanoparticles on leukemia cells. Koh AL, Shachaf CM, Elchuri S, Nolan GP, Sinclair R. Ultramicroscopy. 2008; 109 (1): 111-21
• Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance. Shachaf CM, Gentles AJ, Elchuri S, Sahoo D, Soen Y, Sharpe O, Perez OD, Chang M, Mitchel D, Robinson WH, Dill D, Nolan GP, Plevritis SK, Felsher DW. Cancer Res. 2008; 68 (13): 5132-42
• Differential role of ICAM ligands in determination of human memory T cell differentiation. Perez OD, Mitchell D, Nolan GP. BMC Immunol. 2007: 8 2
• K-RasG12D expression induces hyperproliferation and aberrant signaling in primary hematopoietic stem/progenitor cells. Van Meter ME, Díaz-Flores E, Archard JA, Passegué E, Irish JM, Kotecha N, Nolan GP, Shannon K, Braun BS. Blood. 2007; 109 (9): 3945-52
• Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis. Shachaf CM, Perez OD, Youssef S, Fan AC, Elchuri S, Goldstein MJ, Shirer AE, Sharpe O, Chen J, Mitchell DJ, Chang M, Nolan GP, Steinman L, Felsher DW. Blood. 2007; 110 (7): 2674-84
• RACK1 regulates Ki-Ras-mediated signaling and morphological transformation of NIH 3T3 cells. Bjørndal B, Myklebust LM, Rosendal KR, Myromslien FD, Lorens JB, Nolan G, Bruland O, Lillehaug JR. Int J Cancer. 2007; 120 (5): 961-9
• Single-cell phospho-protein analysis by flow cytometry. Schulz KR, Danna EA, Krutzik PO, Nolan GP. Curr Protoc Immunol. 2007: Chapter 8 Unit 8.17
• Flt3 Y591 duplication and Bcl-2 overexpression are detected in acute myeloid leukemia cells with high levels of phosphorylated wild-type p53. Irish JM, Anensen N, Hovland R, Skavland J, Børresen-Dale AL, Bruserud O, Nolan GP, Gjertsen BT. Blood. 2007; 109 (6): 2589-96
• The ERK mitogen-activated protein kinase pathway contributes to Ebola virus glycoprotein-induced cytotoxicity. Zampieri CA, Fortin JF, Nolan GP, Nabel GJ. J Virol. 2007; 81 (3): 1230-40
• Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry. Irish JM, Czerwinski DK, Nolan GP, Levy R. J Immunol. 2006; 177 (3): 1581-9
• Chemical labeling strategies for cell biology. Marks KM, Nolan GP. Nat Methods. 2006; 3 (8): 591-6
• Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race. He XS, Ji X, Hale MB, Cheung R, Ahmed A, Guo Y, Nolan GP, Pfeffer LM, Wright TL, Risch N, Tibshirani R, Greenberg HB. Hepatology. 2006; 44 (2): 352-9
• Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells. Irish JM, Czerwinski DK, Nolan GP, Levy R. Blood. 2006; 108 (9): 3135-42
• Deeper insights into hematological oncology disorders via single-cell phospho-signaling analysis. Nolan GP, Hematology Am Soc Hematol Educ Program. 2006: 123-7, 509
• Phospho-proteomic immune analysis by flow cytometry: from mechanism to translational medicine at the single-cell level. Perez OD, Nolan GP. Immunol Rev. 2006: 210 208-28
• Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling. Krutzik PO, Nolan GP. Nat Methods. 2006; 3 (5): 361-8
• Luminescent imaging of beta-galactosidase activity in living subjects using sequential reporter-enzyme luminescence. Wehrman TS, von Degenfeld G, Krutzik PO, Nolan GP, Blau HM. Nat Methods. 2006; 3 (4): 295-301
• Phospho-specific flow cytometry: intersection of immunology and biochemistry at the single-cell level. Hale MB, Nolan GP. Curr Opin Mol Ther. 2006; 8 (3): 215-24
• Gene therapy progress and prospects: novel gene therapy approaches for AIDS. Wolkowicz R, Nolan GP. Gene Ther. 2005; 12 (6): 467-76
• Multiparameter analysis of intracellular phosphoepitopes in immunophenotyped cell populations by flow cytometry. Perez OD, Mitchell D, Campos R, Gao GJ, Li L, Nolan GP. Curr Protoc Cytom. 2005: Chapter 6 Unit 6.20
• T-cell tropism and the role of ORF66 protein in pathogenesis of varicella-zoster virus infection. Schaap A, Fortin JF, Sommer M, Zerboni L, Stamatis S, Ku CC, Nolan GP, Arvin AM. J Virol. 2005; 79 (20): 12921-33
• Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry. Krutzik PO, Clutter MR, Nolan GP. J Immunol. 2005; 175 (4): 2357-65
• Characterization of the murine immunological signaling network with phosphospecific flow cytometry. Krutzik PO, Hale MB, Nolan GP. J Immunol. 2005; 175 (4): 2366-73
• Y-box-binding protein 1 confers EGF independence to human mammary epithelial cells. Berquin IM, Pang B, Dziubinski ML, Scott LM, Chen YQ, Nolan GP, Ethier SP. Oncogene. 2005; 24 (19): 3177-86
• Tadpoles by the tail. Nolan GP, Nat Methods. 2005; 2 (1): 11-2
• A random peptide library fused to CCR5 for selection of mimetopes expressed on the mammalian cell surface via retroviral vectors. Wolkowicz R, Jager GC, Nolan GP. J Biol Chem. 2005; 280 (15): 15195-201
• Screening of retroviral cDNA libraries for factors involved in protein phosphorylation in signaling cascades. Stitz J, Krutzik PO, Nolan GP. Nucleic Acids Res. 2005; 33 (4): e39
• Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications. Krutzik PO, Irish JM, Nolan GP, Perez OD. Clin Immunol. 2004; 110 (3): 206-21
• Prolonged liver-specific transgene expression by a non-primate lentiviral vector. Condiotti R, Curran MA, Nolan GP, Giladi H, Ketzinel-Gilad M, Gross E, Galun E. Biochem Biophys Res Commun. 2004; 320 (3): 998-1006
• Lentiviral vectors for the delivery of DNA into mammalian cells. Wolkowicz R, Nolan GP, Curran MA. Methods Mol Biol. 2004: 246 391-411
• Flow cytometric analysis of kinase signaling cascades. Perez OD, Krutzik PO, Nolan GP. Methods Mol Biol. 2004: 263 67-94
• Oligonucleotide-directed site-specific integration of high complexity libraries into ssDNA templates. Hale MB, Nolan GP, Wolkowicz R. Nucleic Acids Res. 2004; 32 (2): e22
• Retroviral technology--applications for expressed peptide libraries. Wolkowicz R, Nolan GP. Front Biosci. 2003: 8 d603-19
• Polyclonal antibodies to xenogeneic endothelial cells induce apoptosis and block support of tumor growth in mice. Scappaticci FA, Contreras A, Boswell CA, Lewis JS, Nolan G. Vaccine. 2003; 21 (19-20): 2667-77
• Localized expression of an anti-TNF single-chain antibody prevents development of collagen-induced arthritis. Smith R, Tarner IH, Hollenhorst M, Lin C, Levicnik AU, Fathman CG, Nolan GP. Gene Ther. 2003; 10 (15): 1248-57
• Treatment of autoimmune disease by adoptive cellular gene therapy. Tarner IH, Slavin AJ, McBride J, Levicnik A, Smith R, Nolan GP, Contag CH, Fathman CG. Ann N Y Acad Sci. 2003: 998 512-9
• Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides. Pashine A, Busch R, Belmares MP, Munning JN, Doebele RC, Buckingham M, Nolan GP, Mellins ED. Immunity. 2003; 19 (2): 183-92
• Recombinant feline immunodeficiency virus vectors. Preparation and use. Curran MA, Nolan GP. Methods Mol Med. 2002: 69 335-50
• Expression from second-generation feline immunodeficiency virus vectors is impaired in human hematopoietic cells. Price MA, Case SS, Carbonaro DA, Yu XJ, Petersen D, Sabo KM, Curran MA, Engel BC, Margarian H, Abkowitz JL, Nolan GP, Kohn DB, Crooks GM. Mol Ther. 2002; 6 (5): 645-52
• Efficient transduction of pancreatic islets by feline immunodeficiency virus vectors1. Curran MA, Ochoa MS, Molano RD, Pileggi A, Inverardi L, Kenyon NS, Nolan GP, Ricordi C, Fenjves ES. Transplantation. 2002; 74 (3): 299-306
• Recognizing a something when your library sees it. Fortin JF, Nolan GP. Chem Biol. 2002; 9 (6): 670-2
• Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression. Fletcher BS, Dragstedt C, Notterpek L, Nolan GP. Leukemia. 2002; 16 (8): 1507-18
• Nonprimate lentiviral vectors. Curran MA, Nolan GP. Curr Top Microbiol Immunol. 2002: 261 75-105
• Motexafin gadolinium (Gd-Tex) selectively induces apoptosis in HIV-1 infected CD4+ T helper cells. Perez OD, Nolan GP, Magda D, Miller RA, Herzenberg LA, Herzenberg LA. Proc Natl Acad Sci U S A. 2002; 99 (4): 2270-4
• Combination angiostatin and endostatin gene transfer induces synergistic antiangiogenic activity in vitro and antitumor efficacy in leukemia and solid tumors in mice. Scappaticci FA, Smith R, Pathak A, Schloss D, Lum B, Cao Y, Johnson F, Engleman EG, Nolan GP. Mol Ther. 2001; 3 (2): 186-96
• A functional screen for genes inducing epidermal growth factor autonomy of human mammary epithelial cells confirms the role of amphiregulin. Berquin IM, Dziubinski ML, Nolan GP, Ethier SP. Oncogene. 2001; 20 (30): 4019-28
• Retroviral transduction of a T cell receptor specific for an Epstein-Barr virus-encoded peptide. Orentas RJ, Roskopf SJ, Nolan GP, Nishimura MI. Clin Immunol. 2001; 98 (2): 220-8
• Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription. Staal FJ, Meeldijk J, Moerer P, Jay P, van de Weerdt BC, Vainio S, Nolan GP, Clevers H. Eur J Immunol. 2001; 31 (1): 285-93
• Statin-AE: a novel angiostatin-endostatin fusion protein with enhanced antiangiogenic and antitumor activity. Scappaticci FA, Contreras A, Smith R, Bonhoure L, Lum B, Cao Y, Engleman EG, Nolan GP. Angiogenesis. 2001; 4 (4): 263-8
• Genetic selection and the lure of SIN. Nolan GP, Nat Biotechnol. 2001; 19 (9): 824-5
• Retroviral and lentiviral gene therapy for autoimmune disease. Smith R, Nolan GP. Curr Dir Autoimmun. 2000: 2 167-88
• Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease. Costa GL, Benson JM, Seroogy CM, Achacoso P, Fathman CG, Nolan GP. J Immunol. 2000; 164 (7): 3581-90
• Neurotrophin dependence domain: a domain required for the mediation of apoptosis by the p75 neurotrophin receptor. Rabizadeh S, Ye X, Sperandio S, Wang JJ, Ellerby HM, Ellerby LM, Giza C, Andrusiak RL, Frankowski H, Yaron Y, Moayeri NN, Rovelli G, Evans CJ, Butcher LL, Nolan GP, Assa-Munt N, Bredesen DE. J Mol Neurosci. 2000; 15 (3): 215-29
• Expression of a peptide binding to receptor for activated C-kinase (RACK1) inhibits phorbol myristoyl acetate-stimulated phospholipase D activity in C3H/10T1/2 cells: dissociation of phospholipase D-mediated phosphatidylcholine breakdown from its synthesis. Thorsen VA, Bjørndal B, Nolan G, Fukami MH, Bruland O, Lillehaug JR, Holmsen H. Biochim Biophys Acta. 2000; 1487 (2-3): 163-76
• Efficient transduction of nondividing cells by optimized feline immunodeficiency virus vectors. Curran MA, Kaiser SM, Achacoso PL, Nolan GP. Mol Ther. 2000; 1 (1): 31-8
• Identification of RIP3, a RIP-like kinase that activates apoptosis and NFkappaB. Yu PW, Huang BC, Shen M, Quast J, Chan E, Xu X, Nolan GP, Payan DG, Luo Y. Curr Biol. 1999; 9 (10): 539-42
• Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts. Vaziri H, Squire JA, Pandita TK, Bradley G, Kuba RM, Zhang H, Gulyas S, Hill RP, Nolan GP, Benchimol S. Mol Cell Biol. 1999; 19 (3): 2373-9
• Local delivery of TNF by retrovirus-transduced T lymphocytes exacerbates experimental autoimmune encephalomyelitis. Dal Canto RA, Shaw MK, Nolan GP, Steinman L, Fathman CG. Clin Immunol. 1999; 90 (1): 10-4
• Single cell analysis and selection of living retrovirus vector-corrected mucopolysaccharidosis VII cells using a fluorescence-activated cell sorting-based assay for mammalian beta-glucuronidase enzymatic activity. Lorincz MC, Parente MK, Roederer M, Nolan GP, Diwu Z, Martin DI, Herzenberg LA, Wolfe JH. J Biol Chem. 1999; 274 (2): 657-65
• NF-kappaB to the rescue: RELs, apoptosis and cellular transformation. Foo SY, Nolan GP. Trends Genet. 1999; 15 (6): 229-35
• Growth inhibition and apoptosis due to restoration of E2A activity in T cell acute lymphoblastic leukemia cells. Park ST, Nolan GP, Sun XH. J Exp Med. 1999; 189 (3): 501-8
• Generation of retroviral vector for clinical studies using transient transfection. Yang S, Delgado R, King SR, Woffendin C, Barker CS, Yang ZY, Xu L, Nolan GP, Nabel GJ. Hum Gene Ther. 1999; 10 (1): 123-32
• Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells. Hitoshi Y, Lorens J, Kitada SI, Fisher J, LaBarge M, Ring HZ, Francke U, Reed JC, Kinoshita S, Nolan GP. Immunity. 1998; 8 (4): 461-71
• Local delivery of cytokines by retrovirally transduced antigen-specific TCR+ hybridoma cells in experimental autoimmune encephalomyelitis. Dal Canto RA, Costa G, Shaw MD, Seroogy C, Nolan GP, Fathman CG. Eur Cytokine Netw. 1998; 9 (3 Suppl): 83-91
• High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein. Grignani F, Kinsella T, Mencarelli A, Valtieri M, Riganelli D, Grignani F, Lanfrancone L, Peschle C, Nolan GP, Pelicci PG. Cancer Res. 1998; 58 (1): 14-9
• Expression vectors and delivery systems. Nolan GP, Shatzman AR. Curr Opin Biotechnol. 1998; 9 (5): 447-50
• Engineered virus targets HIV-infected cells: interview with Garry Nolan, Ph.D. Interview by John S. James. Nolan G, AIDS Treat News. 1997; (No 279): 1, 3-5
• Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3. Heemskerk MH, Blom B, Nolan G, Stegmann AP, Bakker AQ, Weijer K, Res PC, Spits H. J Exp Med. 1997; 186 (9): 1597-602
• Introduction of soluble proteins into the MHC class I pathway by conjugation to an HIV tat peptide. Kim DT, Mitchell DJ, Brockstedt DG, Fong L, Nolan GP, Fathman CG, Engleman EG, Rothbard JB. J Immunol. 1997; 159 (4): 1666-8
• Local delivery of interleukin 4 by retrovirus-transduced T lymphocytes ameliorates experimental autoimmune encephalomyelitis. Shaw MK, Lorens JB, Dhawan A, DalCanto R, Tse HY, Tran AB, Bonpane C, Eswaran SL, Brocke S, Sarvetnick N, Steinman L, Nolan GP, Fathman CG. J Exp Med. 1997; 185 (9): 1711-4
• Identification of an oncogenic form of the thrombopoietin receptor MPL using retrovirus-mediated gene transfer. Onishi M, Mui AL, Morikawa Y, Cho L, Kinoshita S, Nolan GP, Gorman DM, Miyajima A, Kitamura T. Blood. 1996; 88 (4): 1399-406
• Transglutaminase 1 delivery to lamellar ichthyosis keratinocytes. Choate KA, Kinsella TM, Williams ML, Nolan GP, Khavari PA. Hum Gene Ther. 1996; 7 (18): 2247-53
• Applications of retrovirus-mediated expression cloning. Onishi M, Kinoshita S, Morikawa Y, Shibuya A, Phillips J, Lanier LL, Gorman DM, Nolan GP, Miyajima A, Kitamura T. Exp Hematol. 1996; 24 (2): 324-9
• Simultaneous fluorescence-activated cell sorter analysis of two distinct transcriptional elements within a single cell using engineered green fluorescent proteins. Anderson MT, Tjioe IM, Lorincz MC, Parks DR, Herzenberg LA, Nolan GP, Herzenberg LA. Proc Natl Acad Sci U S A. 1996; 93 (16): 8508-11
• Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette. Hofmann A, Nolan GP, Blau HM. Proc Natl Acad Sci U S A. 1996; 93 (11): 5185-90
• Enzyme-generated intracellular fluorescence for single-cell reporter gene analysis utilizing Escherichia coli beta-glucuronidase. Lorincz M, Roederer M, Diwu Z, Herzenberg LA, Nolan GP. Cytometry. 1996; 24 (4): 321-9
• NF-kappa B homodimer binding within the HIV-1 initiator region and interactions with TFII-I. Montano MA, Kripke K, Norina CD, Achacoso P, Herzenberg LA, Roy AL, Nolan GP. Proc Natl Acad Sci U S A. 1996; 93 (22): 12376-81
• Efficient screening of retroviral cDNA expression libraries. Kitamura T, Onishi M, Kinoshita S, Shibuya A, Miyajima A, Nolan GP. Proc Natl Acad Sci U S A. 1995; 92 (20): 9146-50
• Activation of the transcription factor NF-KB in GH3 pituitary cells. Grandison L, Nolan GP, Pfaff DW. Mol Cell Endocrinol. 1994; 106 (1-2): 9-15
• The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner. Nolan GP, Fujita T, Bhatia K, Huppi C, Liou HC, Scott ML, Baltimore D. Mol Cell Biol. 1993; 13 (6): 3557-66
• The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers. Fujita T, Nolan GP, Liou HC, Scott ML, Baltimore D. Genes Dev. 1993; 7 (7B): 1354-63
• The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms. Scott ML, Fujita T, Liou HC, Nolan GP, Baltimore D. Genes Dev. 1993; 7 (7A): 1266-76
• Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B. Fujita T, Nolan GP, Ghosh S, Baltimore D. Genes Dev. 1992; 6 (5): 775-87
• The NF-kappa B p50 precursor, p105, contains an internal I kappa B-like inhibitor that preferentially inhibits p50. Liou HC, Nolan GP, Ghosh S, Fujita T, Baltimore D. EMBO J. 1992; 11 (8): 3003-9
• In situ detection of stage-specific genes and enhancers in B cell differentiation via gene-search retroviruses. Kerr WG, Nolan GP, Johnsen JB, Herzenberg LA. Adv Exp Med Biol. 1991: 292 187-200
• Improved FACS-Gal: flow cytometric analysis and sorting of viable eukaryotic cells expressing reporter gene constructs. Fiering SN, Roederer M, Nolan GP, Micklem DR, Parks DR, Herzenberg LA. Cytometry. 1991; 12 (4): 291-301
• A novel fluorescence-based system for assaying and separating live cells according to VDJ recombinase activity. Yancopoulos GD, Nolan GP, Pollock R, Prockop S, Li SC, Herzenberg LA, Alt FW. Mol Cell Biol. 1990; 10 (4): 1697-704
• Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor. Fiering S, Northrop JP, Nolan GP, Mattila PS, Crabtree GR, Herzenberg LA. Genes Dev. 1990; 4 (10): 1823-34
• Transcriptionally defective retroviruses containing lacZ for the in situ detection of endogenous genes and developmentally regulated chromatin. Kerr WG, Nolan GP, Serafini AT, Herzenberg LA. Cold Spring Harb Symp Quant Biol. 1989: 54 Pt 2 767-76
• In situ detection of transcriptionally active chromatin and genetic regulatory elements in individual viable mammalian cells. Kerr WG, Nolan GP, Herzenberg LA. Immunol Suppl. 1989: 2 74-8; discussion 79
• Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2. Nakauchi H, Tagawa M, Nolan GP, Herzenberg LA. Nucleic Acids Res. 1987; 15 (10): 4337-47
• Formal proof that different-size Lyt-2 polypeptides arise from differential splicing and post-transcriptional regulation. Tagawa M, Nakauchi H, Herzenberg LA, Nolan GP. Proc Natl Acad Sci U S A. 1986; 83 (10): 3422-6
• Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions. Nakauchi H, Nolan GP, Hsu C, Huang HS, Kavathas P, Herzenberg LA. Proc Natl Acad Sci U S A. 1985; 82 (15): 5126-30
• Plasmid mapping computer program. Nolan GP, Maina CV, Szalay AA. Nucleic Acids Res. 1984; 12 (1 Pt 2): 717-29
• Molecular weight determination program. Maina CV, Nolan GP, Szalay AA. Nucleic Acids Res. 1984; 12 (1 Pt 2): 695-702