Ash A. Alizadeh, MD/PhD

Clinical Focus

• Lymphoproliferative Disorders
• Multiple Myeloma
• Chronic Lymphocytic Leukemia
• Lymphoma
• Oncology

Honors and Awards

• Clinical Investigator Program: Fellow Award, Stanford University Medical Center (2004-2010)
• Franklin G. Ebaugh, Jr. Award for Outstanding Research, Dept of Medicine, Stanford (2004-2005)
• Sandler Fellow Award, UCSF (2003-2004)
• Medical Scientist Training Program Award, NIH (1996-2003)
• Research Scholar Award for Outstanding Research, HHMI (1998)

Professional Education

Graduate & Fellowship Program Affiliations

• Biochemistry
• Biophysics
• Medicine

Web Site Links

• Alizadeh Lab, Stanford University

Current Research Interests

My research is focused on attaining a better understanding of the initiation, maintenance, and progression of lymphoid tumors, and their response to immunochemotherapy toward improving current treatment strategies.

In this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models. I hope to apply this knowledge towards the design of clinical trials in the treatment of patients with lymphoma, leukemia, and myeloma.

Publications

• A pluripotency signature predicts histological transformation and influences survival in follicular lymphoma patients Gentles AJ**, Alizadeh AA** (contributed equally), Lee S, Myklebust JH, Shachaf CM, Shahbaba B, Levy R, Koller D, Plevritis SK.. Blood. 2009
• Molecular outcome prediction in diffuse large-B-cell lymphoma. Alizadeh AA, Gentles AJ, Lossos IS, Levy R. N Engl J Med. 2009; 360 (26): 2794-5
• CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Majeti R, Chao MP, Alizadeh AA, Pang WW, Jaiswal S, Gibbs KD, van Rooijen N, Weissman IL. Cell. 2009; 138 (2): 286-99
• SOURCE: a unified genomic resource of functional annotations, ontologies, and gene expression data. Diehn M, Sherlock G, Binkley G, Jin H, Matese JC, Hernandez-Boussard T, Rees CA, Cherry JM, Botstein D, Brown PO, Alizadeh AA. Nucleic Acids Res. 2003; 31 (1): 219-23
• Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Alizadeh AA, Eisen MB, Davis RE, Ma C, Lossos IS, Rosenwald A, Boldrick JC, Sabet H, Tran T, Yu X, Powell JI, Yang L, Marti GE, Moore T, Hudson J, Lu L, Lewis DB, Tibshirani R, Sherlock G, Chan WC, Greiner TC, Weisenburger DD, Armitage JO, Warnke R, Levy R, Wilson W, Grever MR, Byrd JC, Botstein D, Brown PO, Staudt LM. Nature. 2000; 403 (6769): 503-11