Hugh O'Brodovich

Publication Details

• Amiloride-insensitive nasal potential difference varies with the menstrual cycle in cystic fibrosis.

  Sweezey NB, Smith D, Corey M, Ellis L, Carpenter S, Tullis DE, Durie P, O'Brodovich HM. Pediatr Pulmonol. 2007; 42 (6): 519-24

  There is no adequate explanation for gender-based differences in rates of mortality and of deterioration in pulmonary function in cystic fibrosis (CF) patients. One potential explanation is that gender hormones (sex steroids) may modulate the severity of CF lung disease, the principal cause of mortality in CF, by altering respiratory transepithelial ion transport.

  PubMedID: 17469152