Steven R. Alexander, MD
Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)
Contact Information
Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305Brief
The Division of Kidney, Urologic, and Hematologic Diseases (DKUHD) of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), in collaboration with the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Child Health and Human Development (NICHD) and the National Heart, Lung and Blood Institute (NHLBI) funded a cooperative agreement including two Clinical Coordinating Centers and a Data Coordinating Center to conduct a prospective epidemiological study of children with chronic kidney disease (CKD). The primary goals of this study are to determine the risk factors for decline in kidney function and to define how a progressive decline in kidney function impacts neurocognitive function and behavior; the risk factors for cardiovascular disease; and growth failure and its associated morbidity.
Recruiting Status:
Enrolling by InvitationStanford Recruiting Status:
Enrolling by InvitationCondition(s):
Intervention(s):
Phase:
N/AEligibility
Ages Eligible for Study:
1 years to 16 yearsGenders Eligible for Study:
Male and FemaleHealth of Volunteers:
People with the conditions listed in this trial can participate as controls.Key Inclusion Criteria:
Inclusion Criteria:
Age between 1 and 16 years (before 17th birthday)
Estimated (based on SCr) GFR between 30 and 90 ml/min|1.73m2
Willingness and ability to provide informed consent and assent
Key Exclusion Criteria:
Exclusion Criteria:
Renal, other solid organ, bone marrow or stem cell transplantation
Dialysis treatment within the past three months
Cancer/leukemia diagnosis or HIV diagnosis/treatment within last twelve months
Current pregnancy or pregnancy within past twelve months
Inability to complete major data collection procedures (e.g., allergic reaction to iodine or Iohexol)
Current enrollment in a randomized clinical trial in which the specific treatment is unknown
Not fluent in English or Spanish
Plans to move out of area of any participating CKiD site (Families can be transferred to another CKiD site if they move)
History of structural heart disease
Genetic syndromes involving the central nervous system (e.g., Downs syndrome)
History of severe to profound mental retardation (i.e., IQ<40, significant impairment in adaptive function and/or inability to independently execute self-care skills)
Additional Study Details
Official Title:
Chronic Kidney Disease in Children Prospective Cohort Study (CKiD)Anticipated start date:
10/15/2003Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney DiseInvestigator(s):
Study Type:
ObservationalPurpose:
NOTNEEDEDDuration:
LongitudinalSelection:
Defined PopulationTiming:
ProspectiveTotal Number to be Enrolled:
600Total Number to be Enrolled at Stanford:
20More Information
Secondary ID(s):
- 308
Locations & Contacts
Stanford Locations & Contacts:
Stanford University School of Medicine 300 Pasteur Drive Stanford, CA 94305Non-Stanford Locations:
The Stanford website does not have any locations outside of Stanford listed for this trial. You may want to check clinicaltrials.gov for posible additional locations.
This listing was last updated:
12/3/2008PLEASE NOTE:
Study Coordinators and Research Nurses cannot give medical advice over the phone. Telephone numbers are provided for obtaining additional information on specific clinical research trials only. If you have specific questions which require clinical expertise, please call your primary care physician. If you do not have a primary care physician please feel free to call the SHC Physician Referral Service at (800) 756-9000 or send an email.
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