Clare J. Twist
Academic Appointments
- Associate Professor - Med Center Line, Pediatrics - Hematology/Oncology
Contact Information
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Clinical Offices
Pediatric Hematology/Oncology 725 Welch Rd Palo Alto, CA 94304 Tel Work (650) 497-8953 Fax (650) 497-8101Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
- Academic Offices
Personal Information Email Tel (650) 723-5535Not for medical emergencies or patient use
Professional Snapshot
Clinical Focus
- Hematology/Oncology/Stem Cell Transplant, Pediatric
- Oncology (Cancer), Pediatric
- Pediatric Hematology-Oncology
Professional Education
| Board Certification: | Pediatric Hematology-Oncology, American Board of Pediatrics (1994) |
| Fellowship: | Children's Hospital of Boston, MA (1993) |
| Residency: | Children's Memorial Hospital, IL (1990) |
| Internship: | Children's Memorial Hospital, IL (1988) |
| Medical Education: | Albany Medical Center, NY (1987) |
Scientific Focus
Research Interests
My primary research interest is in the study and treatment of neuroblastoma. My clinical interests also include Wilms tumor, hepatoblastoma, post-transplant lymphoproliferative disorders, phase I therapies for hematologic malignancies, as well as palliative and end of life care.
As a clinical investigator in the Children's Oncology Group (COG), I am involved in the clinical trial design of treatment protocols for patients with neuroblastoma, and am the Study Chair for the current COG Phase III Study for the treatment of children with Intermediate Risk Neuroblastoma. I am also the Principal Investigator at Stanford for the New Advances in Neuroblastoma (NANT) Consortium, a limited institution consortium which develops Phase I trials of novel therapies for patients with high risk and recurrent neuroblastoma. I am also interested in new therapies for the treatment of hematologic malignancies and am the Principal Investigator at Stanford for the Therapeutic Advances in Childhood Leukemia (TACL) Consortium, another limited institution consortium specifically dedicated to the development of novel therapies for relapsed leukemias.
Clinical Trials
- Bortezomib With Chemotherapy for Relapsed Pediatric Acute Lymphoblastic Leukemia (ALL) Recruiting
- Intravenous Fenretinide in Treating Young Patients With Recurrent or Resistant Neuroblastoma Recruiting
- Iodine I 131 Metaiodobenzylguanidine, Combination Chemotherapy, and Radiation Therapy in Treating Patients Who Are Undergoing an Autologous Peripheral Stem Cell or Bone Marrow Transplant for Relapsed or Refractory Neuroblastoma Recruiting
- Irinotecan and Vincristine for Radiosensitization of 131I-MIBG Therapy for High-Risk Neuroblastoma Recruiting
- Melphalan and Buthionine Sulfoximine Followed by Stem Cell Transplantation in Children With Resistant or Recurrent Neuroblastoma Recruiting
Publications
- Detection of isolated tumor cells in neuroblastoma by immunohistochemical analysis in bone marrow biopsy specimens: improved detection with use of beta-catenin. Am J Clin Pathol. 2009; (1): 49-57
- Outcome of Patients Treated for Relapsed or Refractory Acute Lymphoblastic Leukemia: A Therapeutic Advances in Childhood Leukemia Consortium Study. J Clin Oncol. 2009
- 123I MIBG mapping with intraoperative gamma probe for recurrent neuroblastoma. Mol Imaging Biol. 2008 Jan-Feb; (1): 19-23
- Precursor B-cell acute lymphoblastic leukemia presenting with hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2008; (2): 381-3
- Effects of human monoclonal antibody 216 on B-progenitor acute lymphoblastic leukemia in vitro. Pediatr Blood Cancer. 2007; (4): 380-6
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