Gerald Crabtree
Publication Details
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Protein acetylation: more than chromatin modification to regulate transcription.
Chem Biol. 1997; (12): 885-8
Histone acetyltransferases and deacetylases are involved in the regulation of gene transcription. Recently, tumor suppressor protein p53 has been shown to be a target for transcriptional coactivators that have histone acetyltransferase activity, suggesting acetylation is also involved in the regulation of cell proliferation and tumorigenesis.
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