Ann Folkins

Publication Details

• Utility of chromosomal chromogenic in situ hybridization as an alternative to flow cytometry and cytogenetics in the diagnosis of early partial hydatidiform moles: a validation study.

  Folkins A, Cruz L, Goldstein DP, Berkowitz RS, Crum C, Kindelberger D. J Reprod Med. 2010 Jul-Aug; 55 (7-8): 275-8

  The introduction of p57 immunohistochemistry has aided the distinction between early complete moles (CMs) and hydropic abortus (HA), but no single technique has emerged for the distinction between early partial moles (PMs) and HA. Flow cytometry and cytogenetics have been used, but these require specialized equipment/expertise. The goal of this study is validation of chromosome in situ hybridization (CrISH), focusing on comparing the results to those obtained by cytogenetic methods.

  PubMedID: 20795338