zzzs
Publications
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FXR Agonist INT-747 Upregulates DDAH Expression and Enhances Insulin Sensitivity in High-Salt Fed Dahl Rats.
Ghebremariam YT,
Yamada K, Lee JC, Johnson CL, Atzler D, Anderssohn M, Agrawal R, Higgins JP, Patterson AJ, Böger RH, Cooke JP.
PLoS One.
2013;
8
(4):
e60653
-
Identification and Characterization of 2 Testicular Germ Cell Markers, Glut3 and CyclinA2.
Howitt BE,
Brooks JD, Jones S, Higgins JP.
Appl Immunohistochem Mol Morphol.
2013
-
Multiple Hepatic Adenomas in a Child with Microvillus Inclusion Disease.
Burgis JC,
Pratt CA, Higgins JP, Kerner JA.
Dig Dis Sci.
2013
-
Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability.
Chernikova SB,
Razorenova OV, Higgins JP, Sishc BJ, Nicolau M, Dorth JA, Chernikova DA, Kwok S, Brooks JD, Bailey SM, Game JC, Brown JM.
Cancer Res.
2012;
72
(8):
2111-9
-
Evaluation of SF-1 Expression in Testicular Germ Cell Tumors: A Tissue Microarray Study of 127 Cases.
Sangoi AR,
McKenney JK, Brooks JD, Higgins JP.
Appl Immunohistochem Mol Morphol.
2012
-
Evaluation of putative renal cell carcinoma markers PAX-2, PAX-8, and hKIM-1 in germ cell tumors: a tissue microarray study of 100 cases.
Sangoi AR,
McKenney JK, Brooks JD, Bonventre JV, Higgins JP.
Appl Immunohistochem Mol Morphol.
2012;
20
(5):
451-3
-
Fibronectin glomerulopathy: an unusual cause of adult-onset nephrotic syndrome.
Nadamuni M,
Piras R, Mazbar S, Higgins JP, Kambham N.
Am J Kidney Dis.
2012;
60
(5):
839-42
-
Statistical analysis of surgical pathology data using the R program.
Cuff J,
Higgins JP.
Adv Anat Pathol.
2012;
19
(3):
131-9
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A tri-marker proliferation index predicts biochemical recurrence after surgery for prostate cancer.
Malhotra S,
Lapointe J, Salari K, Higgins JP, Ferrari M, Montgomery K, van de Rijn M, Brooks JD, Pollack JR.
PLoS One.
2011;
6
(5):
e20293
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C1q-fixing human leukocyte antigen antibodies are specific for predicting transplant glomerulopathy and late graft failure after kidney transplantation.
Yabu JM,
Higgins JP, Chen G, Sequeira F, Busque S, Tyan DB.
Transplantation.
2011;
91
(3):
342-7
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Immunohistochemical distinction of primary adrenal cortical lesions from metastatic clear cell renal cell carcinoma: a study of 248 cases.
Sangoi AR,
Fujiwara M, West RB, Montgomery KD, Bonventre JV, Higgins JP, Rouse RV, Gokden N, McKenney JK.
Am J Surg Pathol.
2011;
35
(5):
678-86
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Specificity of brachyury in the distinction of chordoma from clear cell renal cell carcinoma and germ cell tumors: a study of 305 cases.
Sangoi AR,
Karamchandani J, Lane B, Higgins JP, Rouse RV, Brooks JD, McKenney JK.
Mod Pathol.
2011;
24
(3):
425-9
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A 30-month-old child with acute renal failure due to primary renal cytotoxic T-cell lymphoma.
Paladugu S,
Garro R, Schrijver I, Kambham N, Higgins JP.
Am J Surg Pathol.
2010;
34
(7):
1066-70
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Acute rejection of small intestine allografts is associated with increased expression of toll-like receptors.
Castillo RO,
Wang M, Ito T, Higgins J, Esquivel CO, Krams SM, Martinez OM.
Transplant Proc.
2010;
42
(7):
2676-8
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Ribonucleotide reductase subunit M1 expression in resectable, muscle-invasive urothelial cancer correlates with survival in younger patients.
Harshman LC,
Bepler G, Zheng Z, Higgins JP, Allen GI, Srinivas S.
BJU Int.
2010;
106
(11):
1805-11
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Toll-like receptor 4 contributes to small intestine allograft rejection.
Krams SM,
Wang M, Castillo RO, Ito T, Phillips L, Higgins J, Kambham N, Esquivel CO, Martinez OM.
Transplantation.
2010;
90
(12):
1272-7
-
Treatment with a toll-like receptor inhibitory GpG oligonucleotide delays and attenuates lupus nephritis in NZB/W mice.
Graham KL,
Lee LY, Higgins JP, Steinman L, Utz PJ, Ho PP.
Autoimmunity.
2010;
43
(2):
140-55
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Alteration of gene expression signatures of cortical differentiation and wound response in lethal clear cell renal cell carcinomas.
Zhao H,
Zongming Ma, Tibshirani R, Higgins JP, Ljungberg B, Brooks JD.
PLoS One.
2009;
4
(6):
e6039
-
CD 9 and vimentin distinguish clear cell from chromophobe renal cell carcinoma.
Williams AA,
Higgins JP, Zhao H, Ljunberg B, Brooks JD.
BMC Clin Pathol.
2009:
9
9
-
Expression of the urothelial differentiation markers GATA3 and placental S100 (S100P) in female genital tract transitional cell proliferations.
Esheba GE,
Longacre TA, Atkins KA, Higgins JP.
Am J Surg Pathol.
2009;
33
(3):
347-53
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Immunohistochemical comparison of MUC1, CA125, and Her2Neu in invasive micropapillary carcinoma of the urinary tract and typical invasive urothelial carcinoma with retraction artifact.
Sangoi AR,
Higgins JP, Rouse RV, Schneider AG, McKenney JK.
Mod Pathol.
2009;
22
(5):
660-7
-
Liver abscesses, pylephlebitis, and appendicitis in an adolescent male.
Patel AJ,
Ong PV, Higgins JP, Kerner JA.
Dig Dis Sci.
2009;
54
(12):
2546-8
-
Microtubule-associated protein-2 is a sensitive marker of primary and metastatic neuroblastoma.
Krishnan C,
Higgins JP, West RB, Natkunam Y, Heerema-McKenney A, Arber DA.
Am J Surg Pathol.
2009;
33
(11):
1695-704
-
Recommendations for the reporting of surgically resected specimens of renal cell carcinoma: the Association of Directors of Anatomic and Surgical Pathology.
Higgins JP,
McKenney JK, Brooks JD, Argani P, Epstein JI.
Hum Pathol.
2009;
40
(4):
456-63
-
Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging.
Wheeler HE,
Metter EJ, Tanaka T, Absher D, Higgins J, Zahn JM, Wilhelmy J, Davis RW, Singleton A, Myers RM, Ferrucci L, Kim SK.
PLoS Genet.
2009;
5
(10):
e1000685
-
Bilateral mixed epithelial stromal tumor in an end-stage renal disease patient: the first case report.
Sangoi AR,
Higgins JP.
Hum Pathol.
2008;
39
(1):
142-6
-
Failure of oral atorvastatin to modulate a murine model of systemic lupus erythematosus.
Graham KL,
Lee LY, Higgins JP, Steinman L, Utz PJ, Ho PP.
Arthritis Rheum.
2008;
58
(7):
2098-104
-
IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice.
Thibault DL,
Chu AD, Graham KL, Balboni I, Lee LY, Kohlmoos C, Landrigan A, Higgins JP, Tibshirani R, Utz PJ.
J Clin Invest.
2008;
118
(4):
1417-26
-
Identification of candidate prostate cancer genes through comparative expression-profiling of seminal vesicle.
Thompson M,
Lapointe J, Choi YL, Ong DE, Higgins JP, Brooks JD, Pollack JR.
Prostate.
2008;
68
(11):
1248-56
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hCAP-D3 expression marks a prostate cancer subtype with favorable clinical behavior and androgen signaling signature.
Lapointe J,
Malhotra S, Higgins JP, Bair E, Thompson M, Salari K, Giacomini CP, Ferrari M, Montgomery K, Tibshirani R, van de Rijn M, Brooks JD, Pollack JR.
Am J Surg Pathol.
2008;
32
(2):
205-9
-
Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma.
Chua MS,
Sun H, Cheung ST, Mason V, Higgins J, Ross DT, Fan ST, So S.
Mod Pathol.
2007;
20
(1):
76-83
-
Placental S100 (S100P) and GATA3: markers for transitional epithelium and urothelial carcinoma discovered by complementary DNA microarray.
Higgins JP,
Kaygusuz G, Wang L, Montgomery K, Mason V, Zhu SX, Marinelli RJ, Presti JC, van de Rijn M, Brooks JD.
Am J Surg Pathol.
2007;
31
(5):
673-80
-
The utility of PAX5 immunohistochemistry in the diagnosis of undifferentiated malignant neoplasms.
Jensen KC,
Higgins JP, Montgomery K, Kaygusuz G, van de Rijn M, Natkunam Y.
Mod Pathol.
2007;
20
(8):
871-7
-
CD10 expression in peripheral T-cell lymphomas complicated by a proliferation of large B-cells.
Reichard KK,
Schwartz EJ, Higgins JP, Narasimhan B, Warnke RA, Natkunam Y.
Mod Pathol.
2006;
19
(3):
337-43
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Evaluation of C4d staining in liver and small intestine allografts.
Troxell ML,
Higgins JP, Kambham N.
Arch Pathol Lab Med.
2006;
130
(10):
1489-96
-
Gene array studies in renal neoplasia.
Higgins JP,
ScientificWorldJournal.
2006:
6
502-11
-
Glomerular and tubular basement membrane calcinosis: case report and literature review.
Troxell ML,
Higgins JP, Sibley RK.
Am J Kidney Dis.
2006;
47
(2):
e23-6
-
Intravenous Tamm-Horsfall protein polyps: report of a case in association with a hematoma that mimicked a renal neoplasm.
Higgins JP,
Huie P, Rigaud G, Sibley RK.
Am J Kidney Dis.
2006;
48
(5):
e67-71
-
Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis.
Paniagua RT,
Sharpe O, Ho PP, Chan SM, Chang A, Higgins JP, Tomooka BH, Thomas FM, Song JJ, Goodman SB, Lee DM, Genovese MC, Utz PJ, Steinman L, Robinson WH.
J Clin Invest.
2006;
116
(10):
2633-42
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Tolerizing DNA vaccines for autoimmune arthritis.
Ho PP,
Higgins JP, Kidd BA, Tomooka B, Digennaro C, Lee LY, de Vegvar HE, Steinman L, Robinson WH.
Autoimmunity.
2006;
39
(8):
675-82
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Upregulation of histidine decarboxylase expression in superficial cortical nephrons during pregnancy in mice and women.
Morgan TK,
Montgomery K, Mason V, West RB, Wang L, van de Rijn M, Higgins JP.
Kidney Int.
2006;
70
(2):
306-14
-
A DNA microarray survey of gene expression in normal human tissues.
Shyamsundar R,
Kim YH, Higgins JP, Montgomery K, Jorden M, Sethuraman A, van de Rijn M, Botstein D, Brown PO, Pollack JR.
Genome Biol.
2005;
6
(3):
R22
-
Combined use of the JAK3 inhibitor CP-690,550 with mycophenolate mofetil to prevent kidney allograft rejection in nonhuman primates.
Borie DC,
Larson MJ, Flores MG, Campbell A, Rousvoal G, Zhang S, Higgins JP, Ball DJ, Kudlacz EM, Brissette WH, Elliott EA, Reitz BA, Changelian PS.
Transplantation.
2005;
80
(12):
1756-64
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Correction: A DNA microarray survey of gene expression in normal human tissues.
Shyamsundar R,
Kim YH, Higgins JP, Montgomery K, Jorden M, Sethuraman A, van de Rijn M, Botstein D, Brown PO, Pollack JR.
Genome Biol.
2005;
6
(9):
404
-
Follicular dendritic cell immunohistochemical markers in angioimmunoblastic T-cell lymphoma.
Troxell ML,
Schwartz EJ, van de Rijn M, Ross DT, Warnke RA, Higgins JP, Natkunam Y.
Appl Immunohistochem Mol Morphol.
2005;
13
(4):
297-303
-
Immunosuppression by the JAK3 inhibitor CP-690,550 delays rejection and significantly prolongs kidney allograft survival in nonhuman primates.
Borie DC,
Changelian PS, Larson MJ, Si MS, Paniagua R, Higgins JP, Holm B, Campbell A, Lau M, Zhang S, Flores MG, Rousvoal G, Hawkins J, Ball DA, Kudlacz EM, Brissette WH, Elliott EA, Reitz BA, Morris RE.
Transplantation.
2005;
79
(7):
791-801
-
Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD.
Ermann J,
Hoffmann P, Edinger M, Dutt S, Blankenberg FG, Higgins JP, Negrin RS, Fathman CG, Strober S.
Blood.
2005;
105
(5):
2220-6
-
The effect of soluble complement receptor type 1 on acute humoral xenograft rejection in hDAF-transgenic pig-to-primate life-supporting kidney xenografts.
Lam TT,
Hausen B, Hook L, Lau M, Higgins J, Christians U, Jacobsen W, Baluom M, Duthaler R, Katopodis A, Chavez G, Cozzi E, Harrison R, Schuurman HJ, Borie D, Morris RE.
Xenotransplantation.
2005;
12
(1):
20-9
-
A transcriptional profile of aging in the human kidney.
Rodwell GE,
Sonu R, Zahn JM, Lund J, Wilhelmy J, Wang L, Xiao W, Mindrinos M, Crane E, Segal E, Myers BD, Brooks JD, Davis RW, Higgins J, Owen AB, Kim SK.
PLoS Biol.
2004;
2
(12):
e427
-
Biochemical remission after resection of prostate cancer lung metastasis.
Chao DH,
Higgins JP, Brooks JD.
Urology.
2004;
63
(3):
584-5
-
Gene expression in the normal adult human kidney assessed by complementary DNA microarray.
Higgins JP,
Wang L, Kambham N, Montgomery K, Mason V, Vogelmann SU, Lemley KV, Brown PO, Brooks JD, van de Rijn M.
Mol Biol Cell.
2004;
15
(2):
649-56
-
Gene expression profiling identifies clinically relevant subtypes of prostate cancer.
Lapointe J,
Li C, Higgins JP, van de Rijn M, Bair E, Montgomery K, Ferrari M, Egevad L, Rayford W, Bergerheim U, Ekman P, DeMarzo AM, Tibshirani R, Botstein D, Brown PO, Brooks JD, Pollack JR.
Proc Natl Acad Sci U S A.
2004;
101
(3):
811-6
-
Hyperacute rejection of hDAF-transgenic pig organ xenografts in cynomolgus monkeys: influence of pre-existing anti-pig antibodies and prevention by the alpha GAL glycoconjugate GAS914.
Lam TT,
Hausen B, Boeke-Purkis K, Paniagua R, Lau M, Hook L, Berry G, Higgins J, Duthaler RO, Katopodis AG, Robbins R, Reitz B, Borie D, Schuurman HJ, Morris RE.
Xenotransplantation.
2004;
11
(6):
517-24
-
Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation.
Arber C,
BitMansour A, Sparer TE, Higgins JP, Mocarski ES, Weissman IL, Shizuru JA, Brown JM.
Blood.
2003;
102
(2):
421-8
-
Distribution of monoclonal antiferritin antibody in Kaposi's sarcoma, Hodgkin's disease, and hepatocellular carcinoma.
Yuen AR,
Higgins JP, Baker R, Kamel OW, Warnke RA, Knox SJ.
Hum Pathol.
2003;
34
(4):
381-4
-
Expression of FKBP12 in benign and malignant vascular endothelium: an immunohistochemical study on conventional sections and tissue microarrays.
Higgins JP,
Montgomery K, Wang L, Domanay E, Warnke RA, Brooks JD, van de Rijn M.
Am J Surg Pathol.
2003;
27
(1):
58-64
-
Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarray.
Higgins JP,
Shinghal R, Gill H, Reese JH, Terris M, Cohen RJ, Fero M, Pollack JR, van de Rijn M, Brooks JD.
Am J Pathol.
2003;
162
(3):
925-32
-
Host conditioning with total lymphoid irradiation and antithymocyte globulin prevents graft-versus-host disease: the role of CD1-reactive natural killer T cells.
Lan F,
Zeng D, Higuchi M, Higgins JP, Strober S.
Biol Blood Marrow Transplant.
2003;
9
(6):
355-63
-
Treatment with humanized monoclonal antibodies against CD80 and CD86 combined with sirolimus prolongs renal allograft survival in cynomolgus monkeys.
Bîrsan T,
Hausen B, Higgins JP, Hubble RW, Klupp J, Stalder M, Celniker A, Friedrich S, O'Hara RM, Morris RE.
Transplantation.
2003;
75
(12):
2106-13
-
Gene expression patterns in human liver cancers.
Chen X,
Cheung ST, So S, Fan ST, Barry C, Higgins J, Lai KM, Ji J, Dudoit S, Ng IO, Van De Rijn M, Botstein D, Brown PO.
Mol Biol Cell.
2002;
13
(6):
1929-39
-
Maintenance and recovery stages of postischemic acute renal failure in humans.
Ramaswamy D,
Corrigan G, Polhemus C, Boothroyd D, Scandling J, Sommer FG, Alfrey E, Higgins J, Deen WM, Olshen R, Myers BD.
Am J Physiol Renal Physiol.
2002;
282
(2):
F271-80
-
Unique patterns of surface receptors, cytokine secretion, and immune functions distinguish T cells in the bone marrow from those in the periphery: impact on allogeneic bone marrow transplantation.
Zeng D,
Hoffmann P, Lan F, Huie P, Higgins J, Strober S.
Blood.
2002;
99
(4):
1449-57
-
Allogeneic bone marrow cells that facilitate complete chimerism and eliminate tumor cells express both CD8 and T-cell antigen receptor-alphabeta.
Lan F,
Zeng D, Huie P, Higgins JP, Strober S.
Blood.
2001;
97
(11):
3458-65
-
Apoptosis and allograft rejection in the absence of CD8+ T cells.
Ogura Y,
Martinez OM, Villanueva JC, Tait JF, Strauss HW, Higgins JP, Tanaka K, Esquivel CO, Blankenberg FG, Krams SM.
Transplantation.
2001;
71
(12):
1827-34
-
Coadministration of either cyclosporine or steroids with humanized monoclonal antibodies against CD80 and CD86 successfully prolong allograft survival after life supporting renal transplantation in cynomolgus monkeys.
Hausen B,
Klupp J, Christians U, Higgins JP, Baumgartner RE, Hook LE, Friedrich S, Celnicker A, Morris RE.
Transplantation.
2001;
72
(6):
1128-37
-
Genetic analysis of a papillary thyroid carcinoma in a patient with MEN1.
Desai D,
McPherson LA, Higgins JP, Weigel RJ.
Ann Surg Oncol.
2001;
8
(4):
342-6
-
Long-term plasmapheresis and protein A column treatment of recurrent FSGS.
Belson A,
Yorgin PD, Al-Uzri AY, Salvatierra O, Higgins J, Alexander SR.
Pediatr Nephrol.
2001;
16
(12):
985-9
-
Ovarian non-Hodgkin's lymphoma: a clinicopathologic study of eight primary cases.
Vang R,
Medeiros LJ, Warnke RA, Higgins JP, Deavers MT.
Mod Pathol.
2001;
14
(11):
1093-9
-
Predominance of NK1.1+TCR alpha beta+ or DX5+TCR alpha beta+ T cells in mice conditioned with fractionated lymphoid irradiation protects against graft-versus-host disease: "natural suppressor" cells.
Lan F,
Zeng D, Higuchi M, Huie P, Higgins JP, Strober S.
J Immunol.
2001;
167
(4):
2087-96
-
Pulse methylprednisolone, cyclosporine, and ace inhibitor therapy decreases proteinuria in two siblings with familial focal segmental glomerulosclerosis.
Yorgin PD,
Belson A, Higgins J, Alexander SR.
Am J Kidney Dis.
2001;
37
(6):
E44
-
Large B-cell lymphoma of thyroid. Two cases with a marginal zone distribution of the neoplastic cells.
Higgins JP,
Warnke RA.
Am J Clin Pathol.
2000;
114
(2):
264-70
-
Peripheral T-cell lymphoma complicated by a proliferation of large B cells.
Higgins JP,
van de Rijn M, Jones CD, Zehnder JL, Warnke RA.
Am J Clin Pathol.
2000;
114
(2):
236-47
-
Radiolabeled annexin V imaging: diagnosis of allograft rejection in an experimental rodent model of liver transplantation.
Ogura Y,
Krams SM, Martinez OM, Kopiwoda S, Higgins JP, Esquivel CO, Strauss HW, Tait JF, Blankenberg FG.
Radiology.
2000;
214
(3):
795-800
-
CD30 expression is common in mediastinal large B-cell lymphoma.
Higgins JP,
Warnke RA.
Am J Clin Pathol.
1999;
112
(2):
241-7
-
Herpes lymphadenitis in association with chronic lymphocytic leukemia.
Higgins JP,
Warnke RA.
Cancer.
1999;
86
(7):
1210-5
-
Testicular Sertoli cell tumors NOS, the final word?
Higgins JP,
Rouse RV.
Adv Anat Pathol.
1999;
6
(2):
103-13
-
Management of the clinically positive neck in organ preservation for advanced head and neck cancer.
Dagum P,
Pinto HA, Newman JP, Higgins JP, Terris DJ, Goffinet DR, Fee WE.
Am J Surg.
1998;
176
(5):
448-52
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