Pathology

Department: Pathology

A

  • Academic Appointments
    • Professor - Med Center Line, Pathology
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Pathology and Laboratory Medicine
    Research Interest

    I study molecular genetic and immunophenotypic changes in human hematopoietic neoplasms. These include acute and chronic leukemias, lymphoma, and splenic tumors.

  • Academic Appointments
    • Clinical Associate Professor, Pathology
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Hematopathology
    • Diagnostic Flow Cytometry
    Research Interest

    I am interested in optimizing the process of diagnosing leukemias, lymphomas and other hematolymphoid neoplasms, particularly by the use of diagnostic flow cytometry. One goal is to develop flow data analysis processes that function as interactive tools, allowing pathologists to query rich diagnostic data sets in real time.

  • Academic Appointments
    • Associate Professor, Pathology
    • Member, Bio-X
    • Member, Cancer Center
    Research Interest

    Genetic and cell biological analyses of signals controlling cell polarity and cell proliferation and differentiation. Frizzled signaling and cytoskeletal organization.

B

  • Academic Appointments
    • Assistant Professor - Med Center Line, Pathology
    • Assistant Professor - Med Center Line, Medicine - Infectious Diseases
    Clinical Focus
    • Clinical Pathology
    • Mycobacterium Infections
    • Clinical Laboratory Techniques
    Research Interest

    My research interests include development and implementation of rapid diagnostic assays for the detection, identification, and susceptibility testing of clinically important mycobacteria. Furthermore, I am interested in understanding the role of M. tuberculosis lipoproteins and lipoprotein processing in the pathogenesis of tuberculosis.

  • Academic Appointments
    • Professor - Med Center Line, Pathology
    Clinical Focus
    • Pathology
    • Pathology and Laboratory Medicine
    Research Interest

    In the Microbiology laboratory, we evaluate cutting-edge new technology for rapid diagnosis of infectious diseases, and we work with high-tech companies to help them develop new diagnostic assays at the pre-market stage. We do not perform basic research and we do not have any fellowship support.

  • Academic Appointments
    • Emeritus Faculty, Acad Council, Pathology
  • Academic Appointments
    • Professor - Med Center Line, Pathology
    Clinical Focus
    • Pathology and Laboratory Medicine
    • Anatomic/Clinical Pathology
    Research Interest

    Cardiopulmonary and pulmonary transplant medicine; diagnostic surgical pathology

  • Academic Appointments
    • Clinical Assistant Professor, Pathology
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Pathology
  • Academic Appointments
    • Associate Professor, Pathology
    • Associate Professor, Microbiology & Immunology
    • Associate Professor (By courtesy), Chemical and Systems Biology
    • Member, Bio-X
    • Member, Cancer Center
    Research Interest

    Our lab uses chemical, biochemical, and cell biological methods to study protease function in human disease. Projects include: 1) Design and synthesis of novel chemical probes for each of the primary protease families. 2) Understanding the role of proteolysis in the life cycle of the human parasites, Plasmodium falciparum and Toxoplasma gondii. 3) Defining the specific functional roles of proteases during the process of tumorogenesis. 4) In vivo imaging of protease activity

  • Academic Appointments
    • Professor - Med Center Line, Comparative Medicine
    • Professor - Med Center Line (By courtesy), Pathology
    • Member, Cancer Center
    Research Interest

    Research interests: ocular pathology, host-pathogen interactions in infectious disease, infectious disease in frogs, phenotypic characterization of tg and ko mice, histopathology of minimally-invasive radiological ablation techniques (focused ultrasound, cryoablation).

  • Academic Appointments
    • Assistant Professor - Med Center Line, Pathology
    Research Interest

    My current research involves the investigation of immunoassay interferences from blood collection tube additives; particularly, silicone surfactants.

  • Academic Appointments
    • Acting Assistant Professor, Pathology
  • Academic Appointments
    • Professor, Pathology
    • Member, Cancer Center
    Research Interest

    Our interests include: 1) The physiology and significance of lymphocyte homing in local and systemic immunity; 2) biochemical and genetic studies of molecules that direct leukocyte recruitment; 3) cellular and molecular genetic studies of leukocyte chemotaxis and the role of chemokines; 4) vascular differentiation in normal and pathologic inflammatory states; 5) systems and chemical biology approaches to understanding the regulation of lymphocyte trafficking programs.

C

  • Academic Appointments
    • Instructor, Pathology
  • Academic Appointments
    • Instructor, Pathology
  • Academic Appointments
    • Associate Professor - Med Center Line, Pathology
    • Associate Professor - Med Center Line, Pediatrics
    • Member, Cancer Center
    Clinical Focus
    • Cancer Genetics
    • Clinical Cytogenetics
    • Pathology
    Research Interest

    The use of molecular and molecular cytogenetic methods to identify chromosomal abnormalities in acquired and congenital disorders.

  • Academic Appointments
    • Professor, Pathology
    • Member, Cancer Center
    • Professor, Pediatrics
    Research Interest

    The role of oncoproteins in cancer and development; molecular and cellular biology of hematologic malignancies; targeted molecular therapies of cancer.

  • Academic Appointments
    • Associate Professor - Med Center Line, Pathology
    Clinical Focus
    • Anatomic Pathology
    Research Interest

    My research interests are vascular biology and cardiovascular pathology. We are currently working on gene expression in endothelial cells at sites of pathology.

  • Academic Appointments
    • Emeritus (Active) Associate Professor, Pathology
    Clinical Focus
    • Pathology and Laboratory Medicine
    • Anatomic/Clinical Pathology
    Research Interest

    As medical director of the Hematology Laboratory, my main focus is service work, including laboratory administration, bone marrow pathology, and flow cytometry interpretation. Publications arise primarily from development or evaluation of laboratory methods or collections of unusual patient cases.

  • Academic Appointments
    • Associate Professor - Med Center Line, Pathology
    • Associate Professor - Med Center Line (By courtesy), Pediatrics
    Clinical Focus
    • Pathology
    • Pathology and Laboratory Medicine
    Research Interest

    screening and diagnosis of patients with inborn errors of metabolism, including newborn screening, development of new testing methods and genotype/phenotype correlations.

  • Academic Appointments
    • Professor, Pathology
    • Professor, Developmental Biology
    • Member, Bio-X
    • Member, Cancer Center
    Research Interest

    The role of chromatin in stem cell formation and function. Development of small molecule regulators as experimental probes and therapeutic leads. Signaling through calcineurin and NFAT in vertebrate development.

D

E

F

  • Academic Appointments
    • Associate Professor - Med Center Line, Pathology
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Pathology and Laboratory Medicine
  • Academic Appointments
    • Emeritus Faculty, Acad Council, Pathology
    Research Interest

    Radiation injury in mammalian tissues. Mechanisms of cerebral malaria. Effects of cytokines on angiogenesis.

  • Academic Appointments
    • Associate Professor, Medicine - Oncology
    • Associate Professor, Pathology
    • Member, Bio-X
    • Member, Cancer Center
    Clinical Focus
    • Hodgkin's Disease
    • Hodgkin's Disease - Hematology
    • Hodgkin's Disease - Medical Oncology
    Research Interest

    My laboratory investigates how oncogenes initiate and sustain tumorigenesis. I have developed model systems whereby I can conditionally activate oncogenes in normal human and mouse cells in tissue culture or in specific tissues of transgenic mice. In particular using the tetracycline regulatory system, I have generated a conditional model system for MYC-induced tumors. I have shown that cancers caused by the conditional over-expression of the MYC proto-oncogene regress with its inactivation.

  • Academic Appointments
    • Professor, Pathology
    • Professor, Genetics
    Research Interest

    We study natural cellular mechanisms for adapting to genetic change. These include systems activated during normal development and those for detecting and responding to foreign or unwanted genetic activity. Underlying these studies are questions of how a cells can distinguish information as "self" versus "nonself" or "wanted" versus "unwanted".

  • Academic Appointments
    • Assistant Professor - Med Center Line, Pathology
    Clinical Focus
    • Clinical Pathology
    • Pathology
    Research Interest

    Our interest lies at the frontier of Transfusion Medicine by developing and optimizing new cellular therapies such as islet transplantation for patients with Type 1 Diabetes.

  • Academic Appointments
    • Professor, Pathology
    Clinical Focus
    • Pathology
    • Pathology and Laboratory Medicine
    Research Interest

    Our research focus is on the early events of hepatitis C virus infection- virus attachment and entry into susceptible cells. The approach is through the generation and functional studies of human monoclonal antibodies (HMAbs) to the virus envelope proteins with an emphasis on antibodies to conformational epitopes.

G

  • Academic Appointments
    • Associate Professor - Med Center Line, Pathology
    Clinical Focus
    • Pathology and Laboratory Medicine
    • Pediatric Hematology-Oncology
    Research Interest

    Enhancement of transfusion safety and effectiveness, with a focus on quality assurance in transfusion therapy; transfusion medicine education; pediatric and adult transfusion therapy

  • Academic Appointments
    • Professor, Pathology - Mouse Transgenic Facility
    • Professor, Microbiology & Immunology
    • Member, Bio-X
    • Member, Cancer Center
    Clinical Focus
    • Pathology
    • Pathology and Laboratory Medicine
    Research Interest

    The goals of Dr. Galli's laboratory are to understand the regulation of mast cell and basophil development and the expression of mast cell and basophil function, and to develop and use genetic approaches to elucidate the roles of these cells in health and disease.

  • Academic Appointments
    • Associate Professor - Med Center Line, Pathology
    • Associate Professor - Med Center Line, Pediatrics
    Clinical Focus
    • Pathology and Laboratory Medicine
    • Pediatric Pathology
    Research Interest

    Pediatric Hematopathology, Pediatric Laboratory Medicine and Pathology

  • Academic Appointments
    • Assistant Professor - Med Center Line, Pathology
    • Member, Cancer Center
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Pathology and Laboratory Medicine
    • Hematopathology and Laboratory Hematology
    Research Interest

    Translational research in hematopathology is where my research interests concentrate, including the investigation of the molecular basis of select hematopathology malignancies using fluorescence in situ hybridization, flow cytometry and immunohistochemistry. Areas of study include post-transplant and immunodeficiency-related lymphoproliferative disorders, reactive lymphadenopathies, and the chronic myeloproliferative disorders.

  • Academic Appointments
    • Professor, Pediatrics - Hematology/Oncology
    • Professor (By courtesy), Pathology
    Clinical Focus
    • Pediatric Hematology-Oncology
    • Ped Hematology/Oncology
    Research Interest

    Hematology/Oncology, biology, and treatment of bone marrow failure disorders, hereditary coagulation disorders-clinical trials.

  • Academic Appointments
    • Clinical Assistant Professor, Pathology
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Transfusion Medicine
  • Academic Appointments
    • Professor - Med Center Line, Pathology
    Clinical Focus
    • Pathology
    Research Interest

    Dr. Goodnough has a long-standing interest in alternatives to blood therapy. This includes the concept of antologous blood predonation before elective surgery; acute normovolemic hermodicution;erythropoietic agents to stimulate red blood cell production; pharmacologic strategies to reduce blood loss; artificial oxygen carriers; and re-evaluation of the transfusion trigger. Publications: Goodnough LT: "Erythropoietin", In Scientific Basis of Transfusion Medicine..

  • Academic Appointments
    • Assistant Professor, Pathology
    • Member, Bio-X
    Research Interest

    We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. The main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases.

  • Academic Appointments
    • Assistant Professor - Med Center Line, Pathology
    • Member, Cancer Center
    Clinical Focus
    • Pathology
    • Anatomic/Clinical Pathology
    Research Interest

    I have interests in angiogenesis as well as hematopoietic malignancy. My research currently focuses on vascularity and VEGF signaling in the context of lymphoma.

  • Academic Appointments
    • Clinical Associate Professor, Pathology
  • Academic Appointments
    • Emeritus Faculty, Acad Council, Pathology
    Research Interest

    Work in our laboratory is focused on the study of the human major histocompatibility (HLA) complex. We are seeking to characterize the genes and gene products of this complex and to understand their role in determining transplantation and transfusion compatibility. Laboratory work on this topic ranges from clinical studies correlating graft rejection with HLA antigens identified by classical serology or DNA typing.

H

  • Academic Appointments
    • Clinical Assistant Professor, Pathology
    Clinical Focus
    • Pathology
    • Anatomic/Clinical Pathology
  • Academic Appointments
    • Assistant Professor - Med Center Line, Pathology
    • Assistant Professor - Med Center Line, Pediatrics
    • Member, Cancer Center
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Pathology
    Research Interest

    My scholarly pursuits are primarily focused on the study of death and disease in the pediatric population. It is through this work that I am able to explore fundamental concepts of neoplasia, such as histogenesis and mutagenesis, while utilizing a variety of investigational techniques.

  • Academic Appointments
    • Clinical Assistant Professor, Pathology
    Research Interest

    My research interests are twofold. I am interested in pediatric cancer, specifically hematologic malignancies, and enjoy collaboration with the Children's Oncology Group. I am also interested in placental and perinatal pathology, attempting to understand causes of premature delivery, miscarriage, stillbirth and growth retardation.

  • Academic Appointments
    • Emeritus (Active) Professor, Pathology
    • Emeritus Faculty-Med Ctr Line, Pathology
    Clinical Focus
    • Pathology and Laboratory Medicine
    • Anatomic/Clinical Pathology
    Research Interest

    Diagnosis of progressive stages of uterine cancer; classification of ovarian tumors; breast cancer diagnosis and prognostic factors, soft tissue neoplasm, uterine mesenchymal neoplasm.

  • Academic Appointments
    • Associate Professor - Med Center Line, Pathology
    • Member, Bio-X
    Clinical Focus
    • Pathology and Laboratory Medicine
    • Anatomic/Clinical Pathology
    Research Interest

    I work as a diagnostic surgical pathologist doing tissue and cDNA microarray-based translational research in renal neoplasia and medical renal disease. Subspecialty areas of clinical interest include diagnostic immunohistochemistry, renal, hepatic and transplant pathology.

J

  • Academic Appointments
    • Assistant Professor - Med Center Line, Pathology
    • Member, Cancer Center
    Clinical Focus
    • Pathology
    • Cytopathology
    • Anatomic/Clinical Pathology
    Research Interest

    I am a clinical translational investigator with a primary interest in breast cancer biology, and the use of investigational and clinical ancillary techniques such as gene and tissue microarray analysis and immunohistochemistry in the diagnosis and prognosis of this disease. As a practicing cytopathologist, I also have an interest in improving the fine needle aspiration biopsy diagnosis of breast lesions, again using immunohistochemistry and gene expression analysis as adjuncts to cytomorphology.

K

  • Academic Appointments
    • Associate Professor - Med Center Line, Pathology
    Clinical Focus
    • Pathology and Laboratory Medicine
    • Renal Pathology
    • Anatomic/Clinical Pathology
    Research Interest

    Research interests primarily involve medical diseases of the native and transplant kidney. Other interests include liver transplantation pathology and gastrointestinal pathology.

  • Academic Appointments
    • Emeritus (Active) Professor, Pathology
    • Emeritus Faculty, Acad Council, Pathology
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Pathology and Laboratory Medicine
    Research Interest

    Clinicopathologic studies in endometrial carcinoma, ovarian neoplasms, and soft tissue tumors.

  • Academic Appointments
    • Acting Assistant Professor, Pathology
    Clinical Focus
    • Dermatopathology
    • Pathology
    • Anatomic/Clinical Pathology
  • Academic Appointments
    • Associate Professor - Med Center Line, Pathology
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Pathology and Laboratory Medicine
    Research Interest

    Improving the accuracy of cytologic diagnosis through the use of ancillary techniques on cytology specimens. Evaluating various immunohistochemical markers as potential indicators of prognosis in head and neck squamous cell carcinomas.

  • Academic Appointments
    • Emeritus Faculty, Acad Council, Pathology
  • Academic Appointments
    • Emeritus Faculty, Acad Council, Pathology
    Research Interest

    Methods of evaluation of biopsies; differentiation and, classification of neoplasms; immunohistochemistry; scanning and, transmission electron microscopy; cardiovascular pathology;, histologic assessment of bone biopsies; heart preservation and, restoration; myocardial biopsies; venous autograft coronary artery, bypass; cardial and heart valve transplantation.

  • Academic Appointments
    • Instructor, Pathology - Stem Cell Institute
    Research Interest

    -Stem cell biology & Regenerative Medicine -Stem Cell Derived Immunotherapy for Cancer -BioEngineering -The hematopoietic stem cell niche in murine and human systems -Human T cell differentiation -Humanized animal models -Clinical focus: Bone Marrow/Hematopoietic Stem cell transplantation for malignant and non-malignant diseases in adults & children -Medical devices to enable stem cell based regenerative medicine, to include marrow derived stem cell harvest, processing and delivery

L

  • Academic Appointments
    • Assistant Professor - Med Center Line, Medicine - Hematology
    • Instructor, Pathology
    • Assistant Professor - Med Center Line (By courtesy), Pathology
    • Member, Cancer Center
    Clinical Focus
    • Leukemia, Lymphocytic, Acute
    • Multiple Myeloma
    • Acute Myeloid Leukemia
    Research Interest

    Characterization of the molecular mechanism of MLL-induced acute leukemia and development of new therapeutic strategies for this disease Design of phase I/II trials for the treatment of acute and chronic leukemia and multiple myeloma with novel experimental agents

  • Academic Appointments
    • Professor, Pathology
    • Professor, Genetics
    • Member, Bio-X
    • Member, Cancer Center
    Research Interest

    Function and evolution of the Myb oncogene family; function and evolution of E2F transcriptional regulators and RB tumor suppressors; epigenetic regulation of chromatin and chromosomes; cancer genetics.

  • Academic Appointments
    • Professor - Med Center Line, Pathology
    • Member, Cancer Center
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Pathology and Laboratory Medicine
    Research Interest

    Gynecological, breast and gastrointestinal pathology with major emphasis on ovarian cancer and ovarian tumors of low malignant potential. Pathology of familial and hereditary breast-ovarian-GI cancer.

  • Academic Appointments
    • Assistant Professor, Pathology
    Research Interest

    We are interested in understanding how neural stem cells balance their self-renewal and differentiation and how deregulation of this process can result in brain tumor. We are also interested in mechanisms of neurodegeneration in Alzheimer’s and Parkinson’s diseases. We are using both Drosophila and mammalian models to address these fundamental questions.

M

N

  • Academic Appointments
    • Associate Professor - Med Center Line, Pathology
    • Member, Cancer Center
    Clinical Focus
    • Hematopathology
    • Pathology and Laboratory Medicine
    • Anatomic/Clinical Pathology
    Research Interest

    My research interests focus on the identification and characterization of markers of diagnostic and prognostic importance in hematolymphoid neoplasia.

P

  • Academic Appointments
    • Assistant Professor - Med Center Line, Pathology
    Clinical Focus
    • Anatomic/Clinical Pathology
    Research Interest

    My research interests include cytopathology as well as pancreato-biliary and gastrointestinal pathology.

  • Academic Appointments
    • Instructor, Pathology - Stem Cell Institute
    Clinical Focus
    • Pathology
    • Anatomic/Clinical Pathology
  • Academic Appointments
    • Associate Professor - Med Center Line, Pathology
    • Associate Professor - Med Center Line (By courtesy), Medicine
    Research Interest

    Our laboratory focuses on host-viral interactions in the sexual and mother-to-child transmission of HIV-1. We developed human organotypic models to closely mimic in vivo infection. Our recent work has focused on developing immune-based and small molecule inhibitors of HIV-1 transmission.

  • Academic Appointments
    • Instructor, Pathology
  • Academic Appointments
    • Associate Professor, Pathology
    • Member, Bio-X
    • Member, Cancer Center
    Research Interest

    Our laboratory uses genomics approaches to explore patterns of gene expression and gene copy number alteration in both human cancer cell line model systems and in tumors, with the goals of better understanding cancer, and developing novel diagnostic and therapeutic strategies.

R

  • Academic Appointments
    • Professor (Teaching), Pathology
    • Professor (Teaching) (By courtesy), Orthopaedic Surgery
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Pathology and Laboratory Medicine
    Research Interest

    Autopsy pathology. Medical informatics in pathology: structured reports; diagnostic coding. Orthopedic pathology: implanted prosthetic materials. Medical education: case-based learning in pathology; the use of glass slides, images and specimens in pathology; faculty development (teaching improvement) in the basic medical sciences.

  • Academic Appointments
    • Professor - Med Center Line, Pathology
    Clinical Focus
    • Pathology and Laboratory Medicine
    • Anatomic/Clinical Pathology
    Research Interest

    My recent research efforts are currently focused in the field of applications of immunohistology to the diagnosis of human neoplasms. This work is predominantly aimed at characterizing markers for the identification of non-lymphoid neoplasms and at establishing criteria for their evaluation in diagnostic situations.

S

  • Academic Appointments
    • Instructor, Pathology - Stem Cell Institute
  • Academic Appointments
    • Associate Professor - Med Center Line, Pathology
    • Associate Professor - Med Center Line (By courtesy), Pediatrics
    • Member, Cancer Center
    Clinical Focus
    • Pathology and Laboratory Medicine
    • Clinical Molecular Genetics
    • Anatomic/Clinical Pathology
    Research Interest

    Iris Schrijver is a diplomate of the ABMG, with specialty certification in Clinical Molecular Genetics. In addition, she is a diplomate of the ABP in Clinical Pathology. She is one of the directors of the diagnostic Molecular Pathology laboratory and Stanford Point-of-Care testing. Research interests include the characterization of the molecular basis of inherited disorders, genotype-phenotype correlations, and development of novel molecular diagnostic tools.

  • Academic Appointments
    • Assistant Professor - Med Center Line, Pathology
    Clinical Focus
    • Pathology
    • Anatomic/Clinical Pathology
  • Academic Appointments
    • Associate Professor (Research), Medicine - Infectious Diseases
    • Associate Professor (Research) (By courtesy), Pathology
    Clinical Focus
    • Infectious Disease
    Research Interest

    Dr Shafer's research is on the mechanisms and consequences of HIV evolution with an emphasis on HIV drug resistance. He maintains an online database (http://hivdb.stanford.edu) designed to provide a publicly available resource for those performing HIV drug resistance surveillance, interpreting HIV drug resistance tests, and developing new antiretroviral drugs.

  • Academic Appointments
    • Clinical Instructor, Pathology
    Research Interest

    Clinical chemistry and therapeutic drug monitoring; Screening, detection and quantification of chromosome translocations in leukemia.

  • Academic Appointments
    • Professor, Pathology
    Clinical Focus
    • Pathology and Laboratory Medicine
    • Anatomic/Clinical Pathology
    Research Interest

    Immunologic mechanism of rejection in humans and animal, models of organ transplantation; histological definition of clinical pathology studies of various renal disorders.

  • Academic Appointments
    • Associate Professor, Pathology
    • Associate Professor, Genetics
    • Member, Bio-X
    Research Interest

    We study the function and molecular evolution of proteins and noncoding functional elements in the genome. Please refer to our web site for more information: http://mendel.stanford.edu/SidowLab/index.html

  • Academic Appointments
    • Professor, Pathology
    Research Interest

    We study cellular and molecular mechanisms of immune-mediated injury in central nervous system (CNS) tissues that are altered in multiple sclerosis (MS). Tissues of patients and of animals with experimental allergic encephalomyelitis are analyzed using histology and immunohistochemistry. We currently are studying the cross-recognition of neurons by antibodies against myelin proteolipid protein epitopes. Similar cross-recognition may link anti-myelin immunity with neurodegeneration in MS.

  • Academic Appointments
    • Assistant Professor - Med Center Line, Pathology
    • Assistant Professor - Med Center Line, Dermatology
    Clinical Focus
    • Pathology
    • Anatomic/Clinical Pathology
    Research Interest

    Broad study of extramedullary myeloid tumors; Characterization of CD30+ lymphoproliferative disorders and pathogenesis; Mutational analysis of CD30+ lymphoproliferative disorders; Characterization of cutaneous mast cell disease and distinction from systemic mastocytosis; Comparison of systemic and cutaneous B cell lymphomas by immunohistochemical profiles and the use of tissue microarrays; microRNA studies of cutaneous lymphomas

  • Academic Appointments
    • Professor, Pathology
    Clinical Focus
    • Pathology
    • Pathology and Laboratory Medicine
    Research Interest

    The general problem with which we are concerned is the elucidation of cellular mechanisms of gene regulation which are related to the neoplastic process in humans. The phenomenon of ectopic protein synthesis in human cancer offers a good experimental model for investigating this problem.

T

  • Academic Appointments
    • Clinical Assistant Professor, Pathology
    Clinical Focus
    • Pathology
    • Anatomic/Clinical Pathology
    Research Interest

    My research interest is in the use of molecular methods to understand and characterize hematopoietic neoplasms. My current work focuses on the use of PCR-based assays for clonal rearrangements in the immunoglobulin heavy chain gene (IGH) and T-cell receptor gene (TCR) for the diagnosis of mature T-cell lymphomas.

  • Academic Appointments
    • Professor - Med Center Line, Pathology

V

W

  • Academic Appointments
    • Professor, Pathology
    • Member, Cancer Center
    Research Interest

    The main focus of our research is to understand how cells maintain genome integrity by checkpoint mechanisms during chromosome replication.

  • Academic Appointments
    • Instructor, Pathology
  • Academic Appointments
    • Professor, Pathology
    • Member, Cancer Center
    Clinical Focus
    • Anatomic/Clinical Pathology
    • Pathology and Laboratory Medicine
    Research Interest

    The research in my laboratory involves the application of monoclonal and polyclonal antibodies and a variety of immunohistochemical methods to study human B-cell, T-cell, accessory cell and related neoplasms.

  • Academic Appointments
    • Professor, Pathology - Stem Cell Institute
    • Professor, Developmental Biology
    • Professor (By courtesy), Biology (School of Humanities and Sciences)
    • Member, Bio-X
    • Member, Cancer Center
    Research Interest

    Stem cell and cancer stem cell biology; development of T and B lymphocytes; cell-surface receptors for oncornaviruses in leukemia. Hematopoietic stem cells; Lymphocyte homing, lymphoma invasiveness and metastasis.

  • Academic Appointments
    • Assistant Professor, Pathology - Stem Cell Institute
    Research Interest

    Epigenetic Reprogramming, Pluripotent Stem Cells, Neural Differentiation: implications in development and regenerative medicine

  • Academic Appointments
    • Assistant Professor - Med Center Line, Pathology
    Clinical Focus
    • Pathology and Laboratory Medicine
    • Breast Cancer
    • Sarcoma
    Research Interest

    My laboratory studies the molecular events that lead to and sustain tumorigenesis in soft tissue tumors. We also have an interest in stromal reaction patterns in the microenvironment of cancer.

Z

  • Academic Appointments
    • Professor - Med Center Line, Pathology
    • Professor - Med Center Line, Medicine - Hematology
    • Member, Cancer Center
    Clinical Focus
    • Hematology
    • Pathology
    • Pathology and Laboratory Medicine
    Research Interest

    Our laboratory focuses on translational research in 2 main areas - molecular testing for patients with hematolymphoid malignancy and disorders of thrombosis and hemostasis.

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