{"result":[{"lastName":"Oshima","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Otolaryngology (Head and Neck Surgery)"}],"primaryAppointment":"Instructor,Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9293&type=small&showNoImage","displayName":"Kazuo Oshima","firstName":"Kazuo","href":"http://med.stanford.edu/profiles/Kazuo_Oshima","researchInterest":"Stem cell-based research on the inner ear"},{"lastName":"Cheng","clinicalFocus":[{"focus":"Otolaryngology"},{"focus":"Hearing loss"},{"focus":"Cholesteotoma"},{"focus":"Pediatric sinus disease"},{"focus":"Pediatric head and neck tumors"}],"appointments":[{"appointment":"Assistant Professor,Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Assistant Professor (By courtesy),Pediatrics"}],"primaryAppointment":"Assistant Professor,Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8272&type=small&showNoImage","displayName":"Alan G. Cheng","firstName":"Alan","href":"http://med.stanford.edu/profiles/Alan_Cheng","researchInterest":"Active Wnt signaling maintains somatic stem cells in many organ systems. Using Wnt target genes as markers, we have characterized distinct cell populations with stem cell behavior in the inner ear, an organ thought to be terminally differentiated.  Ongoing work focuses on delineating the developing significance of these putative stem/progenitor cells and their behavior after damage."},{"lastName":"Becker","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)"}],"primaryAppointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13932&type=small&showNoImage","displayName":"Lars Becker","firstName":"Lars","href":"http://med.stanford.edu/profiles/Lars_Becker","researchInterest":""},{"lastName":"Peng","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)"}],"primaryAppointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15399&type=small&showNoImage","displayName":"Anthony Peng","firstName":"Anthony","href":"http://med.stanford.edu/profiles/Anthony_Peng","researchInterest":"Second messenger regulation of mechanotransduction in mammalian hair cells"},{"lastName":"Oghalai","clinicalFocus":[{"focus":"Neurotology"},{"focus":"Cochlear Implantation"},{"focus":"Skull Base Surgery"},{"focus":"Otology"},{"focus":"Schwannomas, Vestibular"},{"focus":"Cholesteatoma"},{"focus":"Otosclerosis"},{"focus":"Otolaryngology"}],"appointments":[{"appointment":"Associate Professor,Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor (By courtesy),Pediatrics"}],"primaryAppointment":"Associate Professor,Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18187&type=small&showNoImage","displayName":"John S. Oghalai","firstName":"John","href":"http://med.stanford.edu/profiles/John_Oghalai","researchInterest":"Hearing loss can begin at any age and tends to progress.  Ultimately, this may lead to deafness.  Our research team seeks to understand the mechanisms of progressive hearing loss, to develop better techniques of diagnosing the cause of hearing loss in individual patients, and to optimize outcomes after cochlear implantation.  We perform translational research using animal models of hearing loss and clinical research in both adult and pediatric patients to accomplish our goals."},{"lastName":"Myers","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stem Cell"}],"primaryAppointment":"Postdoctoral Research fellow, Stem Cell","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13571&type=small&showNoImage","displayName":"Benjamin Myers","firstName":"Benjamin","href":"http://med.stanford.edu/profiles/Benjamin_Myers","researchInterest":""},{"lastName":"Ronaghi","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)"}],"primaryAppointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18186&type=small&showNoImage","displayName":"Mohammad Ronaghi","firstName":"Mohammad","href":"http://med.stanford.edu/profiles/Mohammad_Ronaghi","researchInterest":""},{"lastName":"Longo","clinicalFocus":[{"focus":"Neurology"},{"focus":"Alzheimer's Disease"},{"focus":"Huntington Disease"}],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7249&type=small&showNoImage","displayName":"Frank M. Longo, M.D., Ph.D.","firstName":"Frank","href":"http://med.stanford.edu/profiles/Frank_Longo","researchInterest":"Clinical interests include Alzheimer\u0092s disease and Huntington\u0092s disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders."},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Chemical and Systems Biology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor,Developmental Biology"},{"appointment":"Associate Professor (By courtesy),Natural Sciences Cluster - Chemistry Department"}],"primaryAppointment":"Associate Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3938&type=small&showNoImage","displayName":"James K. Chen","firstName":"James","href":"http://med.stanford.edu/profiles/James_Chen","researchInterest":"Our laboratory combines synthetic chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis.  We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development."},{"lastName":"Ricci","clinicalFocus":[],"appointments":[{"appointment":"Professor,Otolaryngology (Head and Neck Surgery)"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Molecular & Cellular Physiology"}],"primaryAppointment":"Professor,Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7527&type=small&showNoImage","displayName":"Anthony Ricci","firstName":"Anthony","href":"http://med.stanford.edu/profiles/Anthony_Ricci","researchInterest":"The auditory sensory cell, the hair cell, detects mechanical stimulation at the atomic level and conveys information regarding frequency and intensity to the brain with high fidelity. Our interests are in identifying specializations associated with mechanotransduction and synaptic transmission leading to the amazing sensitivities of the auditory system. We are also interested in the developmental process, particularly in how development gives insight into repair and regenerative mechanisms."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Bacaj","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=17260&type=small&showNoImage","displayName":"Taulant Bacaj","firstName":"Taulant","href":"http://med.stanford.edu/profiles/Taulant_Bacaj","researchInterest":""},{"lastName":"Barres","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurobiology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4239&type=small&showNoImage","displayName":"Ben Barres","firstName":"Ben","href":"http://med.stanford.edu/profiles/Ben_Barres","researchInterest":"Our lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system."},{"lastName":"Chai","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)"}],"primaryAppointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13792&type=small&showNoImage","displayName":"Renjie Chai","firstName":"Renjie","href":"http://med.stanford.edu/profiles/Renjie_Chai","researchInterest":""},{"lastName":"Effertz","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)"}],"primaryAppointment":"Postdoctoral Research fellow, Otolaryngology (Head and Neck Surgery)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23948&type=small&showNoImage","displayName":"Thomas Effertz","firstName":"Thomas","href":"http://med.stanford.edu/profiles/Thomas_Effertz","researchInterest":""},{"lastName":"Yang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stem Cell"}],"primaryAppointment":"Postdoctoral Research fellow, Stem Cell","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18228&type=small&showNoImage","displayName":"Nan Yang","firstName":"Nan","href":"http://med.stanford.edu/profiles/Nan_Yang","researchInterest":""},{"lastName":"Mcintire","clinicalFocus":[{"focus":"Neurology"}],"appointments":[{"appointment":"Consulting Associate Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Consulting Associate Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=22953&type=small&showNoImage","displayName":"Steven Mcintire","firstName":"Steven","href":"http://med.stanford.edu/profiles/Steven_Mcintire","researchInterest":""},{"lastName":"Harel","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Genetics"}],"primaryAppointment":"Postdoctoral Research fellow, Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=37895&type=small&showNoImage","displayName":"Itamar Harel","firstName":"Itamar","href":"http://med.stanford.edu/profiles/Itamar_Harel","researchInterest":"The overarching goal of the Brunet lab is to understand the genetic mechanisms of aging and longevity. Aging is a highly plastic process regulated by a combination of genetic and environmental factors. \r\n\r\nI am interested in the basic molecular components that characterize \u0093young\u0094 and \u0093aged\u0094 cellular states. Aging is associated with an increased onset of cancer, and I seeks to define the set of factors that can rejuvenate an aged cell, without the risk of malignant transformation. Ultimately, w"},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Nachury","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Assistant Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8391&type=small&showNoImage","displayName":"Maxence Nachury","firstName":"Maxence","href":"http://med.stanford.edu/profiles/Maxence_Nachury","researchInterest":"We study the primary cilium, a once-obscure cellular organelle recently \"re-discovered\" for its role in a number of signaling pathways. Defects in cilium biogenesis lead to a variety of hereditary disorders characterized by retinal degeneration, kidney cysts and obesity. Our goal is  to characterize these disorders at the molecular and cellular levels to gain insight into the basic mechanisms of primary cilium biogenesis and to discover novel ciliary signaling pathways."},{"lastName":"Ruiz-Lozano","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Pediatrics - Cardiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Associate Professor (Research),Pediatrics - Cardiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18359&type=small&showNoImage","displayName":"Pilar Ruiz-Lozano, Ph.D.","firstName":"Pilar","href":"http://med.stanford.edu/profiles/Pilar_Ruiz-Lozano","researchInterest":"Cardiac development and repair"}]}