Scientific Focus
Publications
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The scaffolding adapter Gab1 mediates vascular endothelial growth factor signaling and is required for endothelial cell migration and capillary formation.
Laramée M,
Chabot C, Cloutier M, Stenne R, Holgado-Madruga M, Wong AJ, Royal I.
J Biol Chem.
2007;
282
(11):
7758-69
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c-Jun NH(2)-terminal kinase 2alpha2 promotes the tumorigenicity of human glioblastoma cells.
Cui J,
Han SY, Wang C, Su W, Harshyne L, Holgado-Madruga M, Wong AJ.
Cancer Res.
2006;
66
(20):
10024-31
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Beta1 integrins modulate cell adhesion by regulating insulin-like growth factor-II levels in the microenvironment.
Goel HL,
Moro L, King M, Teider N, Centrella M, McCarthy TL, Holgado-Madruga M, Wong AJ, Marra E, Languino LR.
Cancer Res.
2006;
66
(1):
331-42
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Host adaptor proteins Gab1 and CrkII promote InlB-dependent entry of Listeria monocytogenes.
Sun H,
Shen Y, Dokainish H, Holgado-Madruga M, Wong A, Ireton K.
Cell Microbiol.
2005;
7
(3):
443-57
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Identification of a specific domain responsible for JNK2alpha2 autophosphorylation.
Cui J,
Holgado-Madruga M, Su W, Tsuiki H, Wedegaertner P, Wong AJ.
J Biol Chem.
2005;
280
(11):
9913-20
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