{"result":[{"lastName":"Ho","clinicalFocus":[{"focus":"Infectious Disease"},{"focus":"Infectious Diseases"},{"focus":"Immunocompromised Host"}],"appointments":[{"appointment":"Clinical Assistant Professor,Medicine - Infectious Diseases"}],"primaryAppointment":"Clinical Assistant Professor,Medicine - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7106&type=small&showNoImage","displayName":"Dora Ho","firstName":"Dora","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Dora_Ho","researchInterest":"Dr. Ho did her PhD work in HSV pathogenesis and postdoctoral research in CNS gene therapy with viral vectors.  Her current interests are in viral and fungal infections in immunocompromised patients and her research focuses on infection complications in neutropenic patients.  In collaboration with Dr. C. Dekker of the Stanford-LPCH Vaccine Program and with Dr. J. Brown of the BMT Division, she is also conducting clinical trials on vaccines, antivirals and antifungals as a co-investigator."},{"lastName":"Giffard","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4657&type=small&showNoImage","displayName":"Rona Giffard","firstName":"Rona","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Rona_Giffard","researchInterest":"The cellular and molecular basis for brain cell injury in stroke is our focus.  Astrocytes and neurons interact, and have unique vulnerabilities to injury based on their patterns of gene expression and their functional roles.  We study gene therapy with heat shock proteins, changes in mitochondrial function, oxidative stress and inflammation during ischemia. We also model cell death pathways and the effects of Hsp70."},{"lastName":"Chan","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4423&type=small&showNoImage","displayName":"Pak H. Chan","firstName":"Pak","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Pak_Chan","researchInterest":"Neuronal death after cerebral ischemia and neural injury using transgenic strategy"},{"lastName":"Dhabhar","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Psychosocial"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Psychosocial","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7313&type=small&showNoImage","displayName":"Firdaus Dhabhar","firstName":"Firdaus","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Firdaus_Dhabhar","researchInterest":"Although stress has a \"bad reputation,\" a physiological stress is response is nature's fundamental survival system. We are interested in identifying mechanisms that mediate and differentiate the recently appreciated immunoenhancing effects of short-term stress from the long-known immunosuppressive effects of chronic stress. We examine stress effects on leukocyte trafficking, innate/adaptive immunity, and cytokine gene/protein expression using models of skin immunity, surgery, and cancer."},{"lastName":"Lindley","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Psychiatry & Behavioral Science - VA & Geriatric"}],"primaryAppointment":"Assistant Professor - Med Center Line,Psychiatry & Behavioral Science - VA & Geriatric","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6056&type=small&showNoImage","displayName":"Steven Lindley","firstName":"Steven","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Steven_Lindley","researchInterest":""},{"lastName":"Steinberg","clinicalFocus":[{"focus":"Neurological Surgery"},{"focus":"Neurosurgery"},{"focus":"Neurosurgery, Pediatric"}],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4646&type=small&showNoImage","displayName":"Gary Steinberg","firstName":"Gary","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Gary_Steinberg","researchInterest":"Our laboratory investigates the pathophysiology and treatment of acute cerebral ischemia, as well as methods to restore neurologic function after stroke. Treatment strategies include mild brain hypothermia, gene transfer therapy and stem cell transplantation. Our clinical research develops innovative surgical, endovascular and radiosurgical approaches for treating patients with difficult intracranial aneurysms, complex vascular malformations and occlusive disease, including Moyamoya disease."},{"lastName":"Palmer","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Neurosurgery"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5930&type=small&showNoImage","displayName":"Theo Palmer","firstName":"Theo","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Theo_Palmer","researchInterest":"For most areas of the mammalian brain, neurogenesis concludes at birth but there are exceptions to the rule. In rodents and humans, some areas of the brain continue to make new neurons throughout life. This process is mediated by neural stem cells and our research goals are to understand how stem cell activity is regulated and whether the nascent potential of resident stem cells can be harnessed for brain repair."},{"lastName":"Schatzberg","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4194&type=small&showNoImage","displayName":"Alan F. Schatzberg","firstName":"Alan","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Alan_Schatzberg","researchInterest":"Biological bases of depressive disorders;, glucocorticoid/dopamine interactions in delusional depression;, pharmacologic treatment of depressive disorders."},{"lastName":"Malenka","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4670&type=small&showNoImage","displayName":"Robert Malenka","firstName":"Robert","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Robert_Malenka","researchInterest":"Long-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy."},{"lastName":"Barreto","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Anesthesia"}],"primaryAppointment":"Postdoctoral Research fellow, Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=11191&type=small&showNoImage","displayName":"George Barreto","firstName":"George","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/George_Barreto","researchInterest":"My interests lie on the glia reactivity and proliferation with aging after focal ischemic injury. Some aims are proposed:\r\n* Role of astrocyte and microglia impairment in focal ischemia;\r\n\r\nand\r\n\r\n* Gene therapy for stroke with superoxide dismutase 2."},{"lastName":"Parker","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor (Research),Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"}],"primaryAppointment":"Assistant Professor (Research),Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7434&type=small&showNoImage","displayName":"Karen J. Parker, Ph.D.","firstName":"Karen","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Karen_Parker","researchInterest":"Oxytocin and vasopressin brain systems and their relationship to social functioning and pathology; stress, coping, and hypothalamic-pituitary-adrenal (HPA) axis physiology; autism and major depression"},{"lastName":"Tsien","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4189&type=small&showNoImage","displayName":"Richard Tsien","firstName":"Richard","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Richard_Tsien","researchInterest":"We study synaptic communication between brain cells with the goal of understanding neuronal computations and memory mechanisms. Main areas of focus include: presynaptic calcium channels, mechanisms of vesicular fusion and recycling. Modulation of synaptic strength through changes in postsynaptic receptors and dendritic morphology. Signaling that links synaptic activity to nuclear transcription and local protein translation. Techniques include imaging, electrophysiology, molecular biology."},{"lastName":"Garner","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","displayName":"Craig C. Garner","firstName":"Craig","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Craig_Garner","researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome."},{"lastName":"de Lecea","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Sleep Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Sleep Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7308&type=small&showNoImage","displayName":"Luis de Lecea","firstName":"Luis","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Luis_de Lecea","researchInterest":"Our group initially identified the hypocretins, two hypothalamic neuropeptides that have a key role in maintaining the states of vigilance. We also discovered cortistatin, a peptide that modulates cortical excitability. My lab uses molecular, pharmacological, anatomical and behavioral methods to identify new roles for these transmitters. We are also interested in the cellular and molecular mechanisms by which neuronal systems integrate homeostatic information and regulate complex behaviors."},{"lastName":"Andreasson","clinicalFocus":[{"focus":"Neurology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Neurology & Neurological Sciences"}],"primaryAppointment":"Associate Professor - Med Center Line,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7903&type=small&showNoImage","displayName":"Katrin Andreasson","firstName":"Katrin","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Katrin_Andreasson","researchInterest":"Our research focuses on understanding disease mechanisms of stroke injury and neurodegenerative diseases such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS) as they relate to the COX-2-prostaglandin pathways.  We are identifying prostaglandin receptor pathways that are involved in these disease models, and our objective is to identify which receptors will be translationally relevant in human neurological disease."},{"lastName":"Pang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9396&type=small&showNoImage","displayName":"Zhiping Pang","firstName":"Zhiping","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Zhiping_Pang","researchInterest":""},{"lastName":"Gupta","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Medical fellow, School of Medicine"}],"primaryAppointment":"Postdoctoral Medical fellow, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9724&type=small&showNoImage","displayName":"Anurag Gupta, MD","firstName":"Anurag","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Anurag_Gupta","researchInterest":""},{"lastName":"Heller","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6225&type=small&showNoImage","displayName":"H Craig Heller","firstName":"H Craig","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/H Craig_Heller","researchInterest":"Neurobiology of sleep, circadian rhythms, regulation of body temperature, mammalian hibernation, and human exercise physiology."},{"lastName":"Goddard","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8925&type=small&showNoImage","displayName":"Carson Goddard","firstName":"Carson","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Carson_Goddard","researchInterest":""},{"lastName":"Dash","clinicalFocus":[],"appointments":[{"appointment":"Acting Assistant Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Acting Assistant Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8685&type=small&showNoImage","displayName":"Rajesh Dash, MD, PhD","firstName":"Rajesh","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Rajesh_Dash","researchInterest":"My research focuses on imaging cell signaling in the heart.  I am developing molecular imaging probes that  track to injured heart tissue, such that non-invasive imaging techniques, like cardiac MRI, can visualize these probe signals in real-time.  The translational goal of my research is to develop new ways to detect early cardiac injury before permanent damage occurs, so that preventive medical therapy can be started."},{"lastName":"Sudhof","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Psychiatry & Behavioral Science"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8533&type=small&showNoImage","displayName":"Thomas Sudhof","firstName":"Thomas","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Thomas_Sudhof","researchInterest":"Information transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice."},{"lastName":"Murphy","clinicalFocus":[{"focus":"Psychiatry"},{"focus":"Geriatric Psychiatry"}],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Neurosciences"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Neurosciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4515&type=small&showNoImage","displayName":"Greer Murphy M.D., Ph.D.","firstName":"Greer","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Greer_Murphy","researchInterest":"Glial cell neurotoxicity and neuroprotection in Alzheimer's disease. Genome wide expression analysis of mouse models for Alzheimer's disease. Pharmacogenetics of mood disorders and nicotine addiction."},{"lastName":"Madison","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Associate Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4321&type=small&showNoImage","displayName":"Daniel V. Madison","firstName":"Vernon","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Vernon_Madison","researchInterest":"Our laboratory uses electrophysiological techniques to study the mechanisms of synaptic transmission and plasticity in the mammalian hippocampus. One of the main focuses in the lab is in the study of synaptic long-term potentiation (LTP). LTP is the persistent increase in synaptic strength that occurs after a period of heavy activity in a synaptic connection. It is the most widely studied and compelling model for mechanisms underlying memory formation in the mammalian central nervous system."},{"lastName":"Longo","clinicalFocus":[{"focus":"Neurology"},{"focus":"Alzheimer's Disease"},{"focus":"Huntington Disease"}],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7249&type=small&showNoImage","displayName":"Frank M. Longo, M.D., Ph.D.","firstName":"Frank","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Frank_Longo","researchInterest":"Clinical interests include Alzheimer\u0092s disease and Huntington\u0092s disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders."},{"lastName":"Moseley","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiology - Diagnostic Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4240&type=small&showNoImage","displayName":"Michael Moseley","firstName":"Michael","href":"http://med.stanford.edu/profiles/neurosurgery/researcher/Michael_Moseley","researchInterest":"MR physics into tissue contrast mechanisms such as diffusion, perfusion, and functional imaging describes the research direction. Applications of cerebral stroke (brain attacks) and neurocognitive disorders are also being developed from these methods"}]}