Gary K. Steinberg, MD, PhD

Publication Details

• Calbindin d28k overexpression protects striatal neurons from transient focal cerebral ischemia.

  Yenari MA, Minami M, Sun GH, Meier TJ, Kunis DM, McLaughlin JR, Ho DY, Sapolsky RM, Steinberg GK. Stroke. 2001; 32 (4): 1028-35

  Increased intracellular calcium accumulation is known to potentiate ischemic injury. Whether endogenous calcium-binding proteins can attenuate this injury has not been clearly established, and existing data are conflicting. Calbindin D28K (CaBP) is one such intracellular calcium buffer. We investigated whether CaBP overexpression is neuroprotective against transient focal cerebral ischemia.

  PubMedID: 11283407