{"result":[{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9396&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Zhiping_Pang","appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"clinicalFocus":[],"firstName":"Zhiping","primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","displayName":"Zhiping Pang","lastName":"Pang"},{"researchInterest":"Long-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4670&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Robert_Malenka","appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"}],"clinicalFocus":[],"firstName":"Robert","primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","displayName":"Robert Malenka","lastName":"Malenka"},{"researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior.  A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions.  In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Craig_Garner","appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Craig","primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","displayName":"Craig C. Garner","lastName":"Garner"},{"researchInterest":"We study synaptic communication between brain cells with the goal of understanding neuronal computations and memory mechanisms. Main areas of focus include: presynaptic calcium channels, mechanisms of vesicular fusion and recycling. Modulation of synaptic strength through changes in postsynaptic receptors and dendritic morphology. Signaling that links synaptic activity to nuclear transcription and local protein translation. Techniques include imaging, electrophysiology, molecular biology.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4189&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Richard_Tsien","appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"}],"clinicalFocus":[],"firstName":"Richard","primaryAppointment":"Professor,Molecular & Cellular Physiology","displayName":"Richard Tsien","lastName":"Tsien"},{"researchInterest":"Our laboratory uses electrophysiological techniques to study the mechanisms of synaptic transmission and plasticity in the mammalian hippocampus. One of the main focuses in the lab is in the study of synaptic long-term potentiation (LTP). LTP is the persistent increase in synaptic strength that occurs after a period of heavy activity in a synaptic connection. It is the most widely studied and compelling model for mechanisms underlying memory formation in the mammalian central nervous system.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4321&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Vernon_Madison","appointments":[{"appointment":"Associate Professor,Molecular & Cellular Physiology"}],"clinicalFocus":[],"firstName":"Vernon","primaryAppointment":"Associate Professor,Molecular & Cellular Physiology","displayName":"Daniel V. Madison","lastName":"Madison"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9452&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Ofer_Yizhar","appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"clinicalFocus":[],"firstName":"Ofer","primaryAppointment":"Postdoctoral Research fellow, Bioengineering","displayName":"Ofer Yizhar","lastName":"Yizhar"},{"researchInterest":"Experiments examine \r\n1)intrinsic properties of neuronal membranes; actions of neurotransmitters that regulate neocortical and thalamic excitability\r\n2) chronic epileptogenesis following cortical injury; changes in intracortical connectivity and receptors; \r\n3) effects of early injury and activity on cortical development/maldevelopment Electrophysiological, anatomical and pharmacological techniques employed.\r\n4. prophylaxis of postraumatic epilepsy\r\n5. Neocortical interneuronal function/modulation","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4531&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/David_Prince","appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"David","primaryAppointment":"Professor,Neurology & Neurological Sciences","displayName":"David Prince","lastName":"Prince"},{"researchInterest":"We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4124&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/John_Huguenard","appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"John","primaryAppointment":"Professor,Neurology & Neurological Sciences","displayName":"John Huguenard","lastName":"Huguenard"},{"researchInterest":"We study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4009&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/M_MacIver","appointments":[{"appointment":"Associate Professor (Research),Anesthesia"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"M","primaryAppointment":"Associate Professor (Research),Anesthesia","displayName":"M Bruce MacIver","lastName":"MacIver"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9949&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Jae Won_Ko","appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"clinicalFocus":[],"firstName":"Jae Won","primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","displayName":"Jae Won Ko","lastName":"Ko"},{"researchInterest":"Research in Dr. Deisseroth's laboratory focuses on developing optical, molecular and cellular tools to observe, perturb, and re-engineer brain circuits. His laboratory is based in the James H. Clark Center at Stanford and has developed optogenetic and tissue engineering methods, employing techniques spanning electrophysiology, molecular biology, optics, neural activity imaging, animal behavior, and computational neural network modeling.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6080&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Karl_Deisseroth","appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Associate Professor,Bioengineering"},{"appointment":"Associate Professor,Psychiatry & Behavioral Science"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[{"focus":"Psychiatry"}],"firstName":"Karl","primaryAppointment":"Assistant Professor,Bioengineering","displayName":"Karl Deisseroth","lastName":"Deisseroth"},{"researchInterest":"Our laboratory studies molecular interactions that underlie the establishment and maintenance of cell and tissue structure.  Our specific areas of interest are the targeted delivery of proteins to intracellular membranes, the architecture and dynamics of intercellular adhesion junctions, and signaling pathways that govern cell fate determination.  We also have a long-standing interest in carbohydrate-based cellular recognition and adhesion.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4259&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/William_Weis","appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"clinicalFocus":[],"firstName":"William","primaryAppointment":"Professor,Structural Biology","displayName":"William Weis","lastName":"Weis"},{"researchInterest":"Our group initially identified the hypocretins, two hypothalamic neuropeptides that have a key role in maintaining the states of vigilance. We also discovered cortistatin, a peptide that modulates cortical excitability. My lab uses molecular, pharmacological, anatomical and behavioral methods to identify new roles for these transmitters. We are also interested in the cellular and molecular mechanisms by which neuronal systems integrate homeostatic information and regulate complex behaviors.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7308&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Luis_de Lecea","appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Sleep Center"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Luis","primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Sleep Center","displayName":"Luis de Lecea","lastName":"de Lecea"},{"researchInterest":"Our lab is interested in the neuronal-glial interactions that underlie the development and function of the mammlian central nervous system.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4239&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Ben_Barres","appointments":[{"appointment":"Professor,Neurobiology"},{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Ophthalmology"},{"appointment":"Member,Bio-X"},{"appointment":"Professor,Developmental Biology"}],"clinicalFocus":[],"firstName":"Ben","primaryAppointment":"Professor,Neurobiology","displayName":"Ben Barres","lastName":"Barres"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9569&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Antony_Boucard","appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"clinicalFocus":[],"firstName":"Antony","primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","displayName":"Antony Boucard","lastName":"Boucard"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9630&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/James_Olzmann","appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"James","primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","displayName":"James Olzmann","lastName":"Olzmann"},{"researchInterest":"Our lab studies the underlying neurobiology of autism and other neuro-developmental disorders.  We are particularly interested in understanding how electrical activity and calcium signals control the development of the brain and how this is altered in children with autism spectrum disorders. We are also developing new tools to study and repair the developing brain.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4040&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Ricardo_Dolmetsch","appointments":[{"appointment":"Assistant Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Ricardo","primaryAppointment":"Assistant Professor,Neurobiology","displayName":"Ricardo Dolmetsch","lastName":"Dolmetsch"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10008&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Stephen_Kaiser","appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"clinicalFocus":[],"firstName":"Stephen","primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","displayName":"Stephen Kaiser","lastName":"Kaiser"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8925&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Carson_Goddard","appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"clinicalFocus":[],"firstName":"Carson","primaryAppointment":"Postdoctoral Research fellow, Neurobiology","displayName":"Carson Goddard","lastName":"Goddard"},{"researchInterest":"Our research is concerned with elucidating the basic cellular molecular mechanisms that underly the recognition and destruction of misfolded or mis-assembled proteins in eukaryotic cells.  We study dominatly inherited human neurodegenerative disorders like Alzheimer's, Huntington's or Parkinson's diseases that are caused by the failure of this system to effectively recognize and destroy such proteins.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6227&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Ron_Kopito","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Ron","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Ron Kopito","lastName":"Kopito"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8794&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Jenny_Johansson","appointments":[{"appointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Jenny","primaryAppointment":"Postdoctoral Research fellow, Neurology & Neurological Sciences","displayName":"Jenny Johansson","lastName":"Johansson"},{"researchInterest":"The main interest of my lab is to understand how the properties of neocortical neurons and the circuits they form give rise to cortical activity and function. Our approach includes recordings from multiple cells, calcium imaging, two-photon imaging and viral-based optogenetic methods to activate  cortical neurons as well as cortical afferents.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4343&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Shaul_Hestrin","appointments":[{"appointment":"Associate Professor,Comparative Medicine"}],"clinicalFocus":[],"firstName":"Shaul","primaryAppointment":"Associate Professor,Comparative Medicine","displayName":"Shaul Hestrin","lastName":"Hestrin"},{"researchInterest":"Use of genetic and molecular tools to dissect immune and inflammatory pathways in Alzheimer's and neurodegeneration.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3929&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Tony_Wyss-Coray","appointments":[{"appointment":"Associate Professor (Research),Neurology & Neurological Sciences"}],"clinicalFocus":[],"firstName":"Tony","primaryAppointment":"Associate Professor (Research),Neurology & Neurological Sciences","displayName":"Tony Wyss-Coray","lastName":"Wyss-Coray"},{"researchInterest":"The goal of research in the Shatz Laboratory is to discover how brain circuits are tuned up by experience during critical periods of development both before and after birth by elucidating cellular and molecular mechanisms that transform early fetal and neonatal brain circuits into mature connections. To discover mechanistic underpinnings of circuit tuning, the lab has conducted functional screens for genes regulated by neural activity and studied their function for vision, learning and memory.","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8146&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Carla_Shatz","appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"clinicalFocus":[],"firstName":"Carla","primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","displayName":"Carla Shatz","lastName":"Shatz"},{"researchInterest":"","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9912&type=small&showNoImage","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Samarjit_Bhattacharyya","appointments":[{"appointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science"}],"clinicalFocus":[],"firstName":"Samarjit","primaryAppointment":"Postdoctoral Research fellow, Psychiatry & Behavioral Science","displayName":"Samarjit Bhattacharyya","lastName":"Bhattacharyya"}]}