{"result":[{"lastName":"Tsien","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4189&type=small&showNoImage","displayName":"Richard Tsien","firstName":"Richard","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Richard_Tsien","researchInterest":"We study synaptic communication between brain cells with the goal of understanding neuronal computations and memory mechanisms. Main areas of focus include: presynaptic calcium channels, mechanisms of vesicular fusion and recycling. Modulation of synaptic strength through changes in postsynaptic receptors and dendritic morphology. Signaling that links synaptic activity to nuclear transcription and local protein translation. Techniques include imaging, electrophysiology, molecular biology."},{"lastName":"Mullins","clinicalFocus":[{"focus":"Pathology"},{"focus":"Molecular Pathology"}],"appointments":[{"appointment":"Instructor,Pathology"}],"primaryAppointment":"Instructor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8576&type=small&showNoImage","displayName":"Franklin Mullins","firstName":"Franklin","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Franklin_Mullins","researchInterest":""},{"lastName":"Yeomans","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Anesthesia"}],"primaryAppointment":"Associate Professor,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3855&type=small&showNoImage","displayName":"David C. Yeomans","firstName":"David","href":"http://med.stanford.edu/profiles/neuroscience/researcher/David_Yeomans","researchInterest":"Physiology of different pain types; Biomarkers of pain and inflammation; Gene Therapy for Pain"},{"lastName":"Liu","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Pulmonary & Critical Care Med"},{"appointment":"Postdoctoral Medical fellow, Medicine"}],"primaryAppointment":"Instructor,Medicine - Pulmonary & Critical Care Med","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9803&type=small&showNoImage","displayName":"Vincent Liu","firstName":"Vincent","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Vincent_Liu","researchInterest":""},{"lastName":"Goodman","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3813&type=small&showNoImage","displayName":"Miriam B. Goodman","firstName":"Miriam","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Miriam_Goodman","researchInterest":"We study the molecular events that give rise to the sensation of touch and temperature in C. elegans. To do this, we use a combination of quantitative behavioral analysis, genetics, in vivo electrophysiology, and heterologous expression of ion channels. We also collaborate with Pruitt's group in Mechanical Engineering to develop and fabricate novel devices for the study of sensory transduction."},{"lastName":"Thompson","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6245&type=small&showNoImage","displayName":"Stuart Thompson","firstName":"Stuart","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Stuart_Thompson","researchInterest":""},{"lastName":"Eastwood","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10621&type=small&showNoImage","displayName":"Amy L Eastwood","firstName":"Amy","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Amy_Eastwood","researchInterest":"Dr. Amy Eastwood\u0092s career has not just bloomed\u0097it has rocketed. From her takeoff in high school where her chemistry teacher inspired her to pursue a career in science, Dr. Eastwood obtained her Ph.D. at Caltech University, which in turn drew her interest to look at her research on ion channels in a more natural environment. \r\n\r\nHouston, we have found C. elegans. Dr. Eastwood came to Stanford University in late 2008 and now, with the Stanford University\u0092s Dean Fellowship and a NIH NRSA Fellows"},{"lastName":"Lewis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4176&type=small&showNoImage","displayName":"Richard Lewis","firstName":"Richard","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Richard_Lewis","researchInterest":"We study molecular mechanisms of calcium signaling with a focus on store-operated CRAC channels and their essential roles in T cell development and function. Currently we aim to define the molecular mechanism for CRAC channel activation and the means by which calcium signal dynamics mediate specific activation of transcription factors and T-cell genes during development."},{"lastName":"Deisseroth","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Associate Professor,Bioengineering"},{"appointment":"Associate Professor,Psychiatry & Behavioral Science"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6080&type=small&showNoImage","displayName":"Karl Deisseroth","firstName":"Karl","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Karl_Deisseroth","researchInterest":"Research in Dr. Deisseroth's laboratory focuses on developing optical, molecular and cellular tools to observe, perturb, and re-engineer brain circuits. His laboratory is based in the James H. Clark Center at Stanford and has developed optogenetic and tissue engineering methods, employing techniques spanning electrophysiology, molecular biology, optics, neural activity imaging, animal behavior, and computational neural network modeling."},{"lastName":"Huguenard","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4124&type=small&showNoImage","displayName":"John Huguenard","firstName":"John","href":"http://med.stanford.edu/profiles/neuroscience/researcher/John_Huguenard","researchInterest":"We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks."},{"lastName":"Blau","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4517&type=small&showNoImage","displayName":"Helen M. Blau","firstName":"Helen","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Helen_Blau","researchInterest":"Molecular and cellular mechanisms that control muscle and neuronal growth; stem cell biology, differentiation, and tumorigenicity. Regulating stem cell fate in vitro and in vivo. Stem cell therapies. Hematopoietic and muscle stem cells. Characterizing and bioengineering stem cell niches. Nuclear reprogramming. Muscle development and disease. Drug delivery. Tracking cell behavior in vitro and in vivo. Understanding tissue degeneration and regeneration."},{"lastName":"McMahan","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Neurobiology"},{"appointment":"Emeritus Faculty, Acad Council,Structural Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4104&type=small&showNoImage","displayName":"Uel Jackson McMahan","firstName":"Uel","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Uel_McMahan","researchInterest":"We are currently investigating mechanisms involved in synaptic transmission and synaptogenesis using electron microscope tomography in ways that provide in situ 3D structural information at macromolecular resolution."},{"lastName":"Liao","clinicalFocus":[{"focus":"Neuro-Ophthalmology "},{"focus":"Ischemic Optic Neuropathy"},{"focus":"Eye Movement Disorders"},{"focus":"Ophthalmology"},{"focus":"Pseudotumor Cerebri"},{"focus":"Diplopia"},{"focus":"Optic Neuritis and Multiple Sclerosis"},{"focus":"Nystagmus"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Ophthalmology"}],"primaryAppointment":"Assistant Professor - Med Center Line,Ophthalmology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7703&type=small&showNoImage","displayName":"Y. Joyce Liao, M.D. Ph.D.","firstName":"Yaping","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Yaping_Liao","researchInterest":"Ischemic optic neuropathy\r\nStem cell transplantation\r\nVision electrophysiology\r\nEye movement disorders\r\n\r\nOptic neuropathy\r\nOptic neuritis\r\nParaneoplastic syndromes"},{"lastName":"Yizhar","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9452&type=small&showNoImage","displayName":"Ofer Yizhar","firstName":"Ofer","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Ofer_Yizhar","researchInterest":""},{"lastName":"Sudhof","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Psychiatry & Behavioral Science"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8533&type=small&showNoImage","displayName":"Thomas Sudhof","firstName":"Thomas","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Thomas_Sudhof","researchInterest":"Information transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice."},{"lastName":"Clusin","clinicalFocus":[{"focus":"Cardiology (Heart)"},{"focus":"Cardiovascular Disease"}],"appointments":[{"appointment":"Associate Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Associate Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4502&type=small&showNoImage","displayName":"William Clusin, MD","firstName":"William","href":"http://med.stanford.edu/profiles/neuroscience/researcher/William_Clusin","researchInterest":"Cardiac action potentials; tissue culture, voltage, clamp technique; role of calcium in ischemia arrhythmias; coronary, artery disease; myocardial infarction."},{"lastName":"Prince","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4531&type=small&showNoImage","displayName":"David Prince","firstName":"David","href":"http://med.stanford.edu/profiles/neuroscience/researcher/David_Prince","researchInterest":"Experiments examine \r\n1)intrinsic properties of neuronal membranes; actions of neurotransmitters that regulate neocortical and thalamic excitability\r\n2) chronic epileptogenesis following cortical injury; changes in intracortical connectivity and receptors; \r\n3) effects of early injury and activity on cortical development/maldevelopment Electrophysiological, anatomical and pharmacological techniques employed.\r\n4. prophylaxis of postraumatic epilepsy\r\n5. Neocortical interneuronal function/modulation"},{"lastName":"Angst","clinicalFocus":[{"focus":"Anesthesia"},{"focus":"Anesthesia for Liver Transplantation"},{"focus":"Neuroanesthesia"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Anesthesia"}],"primaryAppointment":"Associate Professor - Med Center Line,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4553&type=small&showNoImage","displayName":"Martin S. Angst","firstName":"Martin","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Martin_Angst","researchInterest":"Our human pain laboratory is a translational research facility using quantitative, reliable and mechanism-based approaches to study pain and its relief in human biology. We focus on three inter-related areas: the identification of pain biomarkers and potential analgesic targets, the early validation or rejection of novel analgesic interventions, and the pharmacogenomics and proteomics of opioid-analgesics."},{"lastName":"Pang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9396&type=small&showNoImage","displayName":"Zhiping Pang","firstName":"Zhiping","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Zhiping_Pang","researchInterest":""},{"lastName":"Garner","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3890&type=small&showNoImage","displayName":"Craig C. Garner","firstName":"Craig","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Craig_Garner","researchInterest":"Our laboratory is studying synapse formation, stability and elimination at a variety of levels, e.g. from molecules to behavior. A primary focus of the lab is to understanding the role that individual molecules play in the assembly and function of synaptic junctions. In addition we evaluating a variety of potential treatments for cognitive impairment in Down syndrome in part by assessing the impact specific drugs on cognitive function in mouse models of Down syndrome."},{"lastName":"Stockdale","clinicalFocus":[{"focus":"Breast Cancer - Medical Oncology"},{"focus":"Oncology"},{"focus":"Newly Diagnosed Breast Cancer"},{"focus":"Metastatic Breast Cancer"},{"focus":"Inflammatory Breast Cancer"},{"focus":"Locally Advanced Breast Cancer"},{"focus":"Chemotherapy, Adjuvant"},{"focus":"Ductal Carcinoma In Situ"},{"focus":"Phyllodes Tumor"}],"appointments":[{"appointment":"Emeritus (Active) Professor,Medicine - Oncology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Emeritus (Active) Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4528&type=small&showNoImage","displayName":"Frank E. Stockdale","firstName":"Frank","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Frank_Stockdale","researchInterest":"Laboratory and clinical research in breast cancer ; Normal and abornal differentiation and growth"},{"lastName":"Ho","clinicalFocus":[{"focus":"Infectious Disease"},{"focus":"Infectious Diseases"},{"focus":"Immunocompromised Host"}],"appointments":[{"appointment":"Clinical Assistant Professor,Medicine - Infectious Diseases"}],"primaryAppointment":"Clinical Assistant Professor,Medicine - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7106&type=small&showNoImage","displayName":"Dora Ho","firstName":"Dora","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Dora_Ho","researchInterest":"Dr. Ho did her PhD work in HSV pathogenesis and postdoctoral research in CNS gene therapy with viral vectors. Her current interests are in viral and fungal infections in immunocompromised patients and her research focuses on infection complications in neutropenic patients. In collaboration with Dr. C. Dekker of the Stanford-LPCH Vaccine Program and with Dr. J. Brown of the BMT Division, she is also conducting clinical trials on vaccines, antivirals and antifungals as a co-investigator."},{"lastName":"Cornfield","clinicalFocus":[{"focus":"Pediatric Pulmonary"},{"focus":"Pulmonary Medicine/Cystic Fibrosis, Pediatric"}],"appointments":[{"appointment":"Professor,Pediatrics - Pulmonary Medicine"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pediatrics - Pulmonary Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7127&type=small&showNoImage","displayName":"David Cornfield","firstName":"David","href":"http://med.stanford.edu/profiles/neuroscience/researcher/David_Cornfield","researchInterest":""},{"lastName":"Dolmetsch","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4040&type=small&showNoImage","displayName":"Ricardo Dolmetsch","firstName":"Ricardo","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Ricardo_Dolmetsch","researchInterest":"Our lab studies the underlying neurobiology of autism and other neuro-developmental disorders. We are particularly interested in understanding how electrical activity and calcium signals control the development of the brain and how this is altered in children with autism spectrum disorders. We are also developing new tools to study and repair the developing brain."},{"lastName":"Hippenmeyer","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8871&type=small&showNoImage","displayName":"Simon Hippenmeyer","firstName":"Simon","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Simon_Hippenmeyer","researchInterest":""}]}