{"result":[{"lastName":"Helms","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Surgery - Plastic/Recon Surgery"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Surgery - Plastic/Recon Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6152&type=small&showNoImage","displayName":"Jill Helms","firstName":"Jill","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Jill_Helms","researchInterest":"Dr. Helms' research interests center around craniofacial development and regenerative medicine."},{"lastName":"Sidow","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Associate Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4393&type=small&showNoImage","displayName":"Arend Sidow","firstName":"Arend","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Arend_Sidow","researchInterest":"We study the function and molecular evolution of proteins and noncoding functional elements in the genome.  Please refer to our web site for more information:  http://mendel.stanford.edu/SidowLab/index.html"},{"lastName":"Francke","clinicalFocus":[{"focus":"Clinical Genetics"},{"focus":"Neurogenetics"}],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Pediatrics"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4281&type=small&showNoImage","displayName":"Uta Francke","firstName":"Uta","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Uta_Francke","researchInterest":"Functional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models: Williams-Beuren syndrome, a heterozygous 1.6 megabase deletion; Rett syndrome, caused by mutations in the X-linked methyl-CpG binding protein 2 (MECP2) gene. Mechanisms of genomic imprinting: Prader Willi syndrome"},{"lastName":"Buckwalter","clinicalFocus":[{"focus":"Neurology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences"},{"appointment":"Member,Neurology & Neurological Sciences"}],"primaryAppointment":"Assistant Professor - Med Center Line,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6463&type=small&showNoImage","displayName":"Marion S. Buckwalter","firstName":"Marion","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Marion_Buckwalter","researchInterest":"Our lab focuses on how inflammatory responses after brain injury affect neurological recovery. We utilize translational approaches to understand molecular mechanisms underlying functional recovery.  Molecular events are modified in mice using either transgenic models or novel small molecule compounds, and then we evaluate the effects on functional recovery as well as on cellular and molecular responses."},{"lastName":"Feldman","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6220&type=small&showNoImage","displayName":"Marcus Feldman","firstName":"Marcus","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Marcus_Feldman","researchInterest":""},{"lastName":"Barsh","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"},{"appointment":"Professor,Pediatrics - Genetics"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4285&type=small&showNoImage","displayName":"Greg Barsh","firstName":"Gregory","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Gregory_Barsh","researchInterest":"Genetics of color variation"},{"lastName":"Scott","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4165&type=small&showNoImage","displayName":"Matthew Scott","firstName":"Matthew","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Matthew_Scott","researchInterest":"Genetic regulation of animal development and human disease. We use mice and flies to study Hedgehog/Patched signaling and its links to brain cancer, development of the neural tube and cerebellum, planar cell polarity genes, a neurodegenerative disease called Niemann-Pick syndrome that affects intracellular organelle movements, chromatin proteins in embryonic stem cells, and genetic control of body size."},{"lastName":"Quertermous","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4426&type=small&showNoImage","displayName":"Thomas Quertermous, MD","firstName":"Thomas","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Thomas_Quertermous","researchInterest":"Understanding genetic basis of cardiovascular function and disease."},{"lastName":"Petrov","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6234&type=small&showNoImage","displayName":"Dmitri Petrov","firstName":"Dmitri","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Dmitri_Petrov","researchInterest":""},{"lastName":"Davis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4117&type=small&showNoImage","displayName":"Ronald Davis","firstName":"Ronald","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Ronald_Davis","researchInterest":"We are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion."},{"lastName":"Brugmann","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9172&type=small&showNoImage","displayName":"Samantha Brugmann","firstName":"Samantha","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Samantha_Brugmann","researchInterest":"Craniofacial development and  patterning"},{"lastName":"Longaker","clinicalFocus":[{"focus":"Plastic Surgery"},{"focus":"Plastic Surgery, Pediatric"}],"appointments":[{"appointment":"Professor,Surgery - Plastic/Recon Surgery"},{"appointment":"Professor (By courtesy),Bioengineering"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Surgery - Plastic/Recon Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4338&type=small&showNoImage","displayName":"Michael Longaker","firstName":"Michael","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Michael_Longaker","researchInterest":"We have six main areas of current interest: 1) Cranial Suture Developmental Biology, 2)Distraction Osteogenesis, 3) Cleft Palate and Lip Biology, 4)Keloid and Hypertrophic Scar Biology, 5) Scarless Fetal Wound Healing, 6) Novel Gene and Stem Cell Therapeutic Approaches."},{"lastName":"Stockdale","clinicalFocus":[{"focus":"Breast Cancer - Medical Oncology"},{"focus":"Oncology"},{"focus":"Newly Diagnosed Breast Cancer"},{"focus":"Metastatic Breast Cancer"},{"focus":"Inflammatory Breast Cancer"},{"focus":"Locally Advanced Breast Cancer"},{"focus":"Chemotherapy, Adjuvant"},{"focus":"Ductal Carcinoma In Situ"},{"focus":"Phyllodes Tumor"}],"appointments":[{"appointment":"Emeritus (Active) Professor,Medicine - Oncology"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Emeritus (Active) Professor,Medicine - Oncology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4528&type=small&showNoImage","displayName":"Frank E. Stockdale","firstName":"Frank","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Frank_Stockdale","researchInterest":"Laboratory and clinical research in breast cancer ; Normal and abornal differentiation and growth"},{"lastName":"Carter","clinicalFocus":[],"appointments":[{"appointment":"Professor,Mechanical Engineering"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Mechanical Engineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6095&type=small&showNoImage","displayName":"Dennis Carter","firstName":"Dennis","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Dennis_Carter","researchInterest":"Professor Carter studies the influence of mechanical loading upon the growth, development, regeneration, and aging of skeletal tissues. Basic information from such studies is used to understand skeletal diseases and treatments. He has served as President of the Orthopaedic Research Society and is a Fellow of the American Institute for Medical and Biological Engineering."},{"lastName":"Chang","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Medicine - Cardiovascular Medicine"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6387&type=small&showNoImage","displayName":"Ching-Pin Chang","firstName":"Ching-Pin","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Ching-Pin_Chang","researchInterest":"My laboratory studies the mechanisms of cardiovascular development, particularly how the three major types of cardiac cells (endocardial, myocardial and epicardial cells) and neural crest cells interact with each other to generate heart tissues.  We are interested in the transcriptional and signaling events that coordinate their interactions and assembly into heart tissues.  The long-term goal is to understand the developmental mechanisms that control tissue formation and recapitulate the devel"},{"lastName":"Reijo-Pera","clinicalFocus":[],"appointments":[{"appointment":"Professor,Obstetrics & Gynecology - OB GYN Institutes"},{"appointment":"Member,Cancer Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Obstetrics & Gynecology - OB GYN Institutes","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8036&type=small&showNoImage","displayName":"Renee A. Reijo Pera, Ph.D.","firstName":"Renee","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Renee_Reijo-Pera","researchInterest":"The Reijo Pera Laboratory is focused on understanding key cell fates in the embryo, including the generation of pluripotent stem cells, somatic and germ cell lineages"},{"lastName":"Stankunas","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Medicine - Cardiovascular Medicine"}],"primaryAppointment":"Instructor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9759&type=small&showNoImage","displayName":"Kryn Stankunas","firstName":"Kryn","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Kryn_Stankunas","researchInterest":""},{"lastName":"Nusse","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4280&type=small&showNoImage","displayName":"Roeland Nusse","firstName":"Roeland","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Roeland_Nusse","researchInterest":"Our laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We also discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt,  using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during injury repair and regeneration."},{"lastName":"Blau","clinicalFocus":[],"appointments":[{"appointment":"Professor,Microbiology & Immunology - Baxter Laboratory"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Microbiology & Immunology - Baxter Laboratory","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4517&type=small&showNoImage","displayName":"Helen M. Blau","firstName":"Helen","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Helen_Blau","researchInterest":"Molecular and cellular mechanisms that control muscle and neuronal growth; stem cell biology, differentiation, and tumorigenicity. Regulating stem cell fate in vitro and in vivo. Stem cell therapies. Hematopoietic and muscle stem cells. Characterizing and bioengineering stem cell niches. Nuclear reprogramming. Muscle development and disease. Drug delivery. Tracking cell behavior in vitro and in vivo. Understanding tissue degeneration and regeneration."},{"lastName":"Brown","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biochemistry"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Biochemistry","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4284&type=small&showNoImage","displayName":"Patrick O. Brown","firstName":"Patrick","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Patrick_Brown","researchInterest":"Dr. Brown's research group uses diverse experimental and computational methods to investigate the logic and mechanisms that control a genome's expression program.  The Brown laboratory is systematically characterizing the genetic scripts that control the expression of our genes, in normal development and physiology and in diseases like cancer, with a particular focus on post-transcriptional regulation. The Brown lab also develops strategies and assays for early detection and diagnosis of cancer."},{"lastName":"Axelrod","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Associate Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4410&type=small&showNoImage","displayName":"Jeffrey Axelrod","firstName":"Jeffrey","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Jeffrey_Axelrod","researchInterest":"Genetic and cell biological analyses of signals controlling cell polarity and cell proliferation and differentiation.  Frizzled signaling and cytoskeletal organization."},{"lastName":"Reimer","clinicalFocus":[{"focus":"Neurology"}],"appointments":[{"appointment":"Assistant Professor,Neurology & Neurological Sciences"},{"appointment":"Assistant Professor (By courtesy),Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3819&type=small&showNoImage","displayName":"Richard J. Reimer, MD","firstName":"Richard","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Richard_Reimer","researchInterest":"Reimer Lab interests\r\n\r\nA primary interest of our lab is to understand how nerve cells make and recycle neurotransmitters, the small molecules that they use to communicate with each other. In better defining these processes we hope to achieve our long-term goal of identifying novel sites for treatment of diseases such as epilepsy and Parkinson Disease. In our studies on neurotransmitter metabolism we have focused our efforts on transporters, a functional class of proteins that move neurotransmi"},{"lastName":"Crabtree","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Professor,Developmental Biology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4283&type=small&showNoImage","displayName":"Gerald Crabtree","firstName":"Gerald","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Gerald_Crabtree","researchInterest":"The role of chromatin in stem cell formation and function.  Development of small molecule regulators as experimental probes and therapeutic leads.  Signaling through calcineurin  and NFAT in vertebrate development."},{"lastName":"Smith","clinicalFocus":[],"appointments":[{"appointment":"Professor (Research),Orthopaedic Surgery"},{"appointment":"Professor (Research) (By courtesy),Mechanical Engineering"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor (Research),Orthopaedic Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4314&type=small&showNoImage","displayName":"Robert Lane Smith","firstName":"R","href":"http://med.stanford.edu/profiles/neuroscience/researcher/R_Smith","researchInterest":"Our group is interested in the molecular and cell biology underlying bone and cartilage metabolism in health and disease. Normal daily activities are linked to the ability of the articular cartilage to withstand normal joint forces that may reach 5-7 times body weight and bone homeostasis depends on daily mechanical loading histories."},{"lastName":"Calos","clinicalFocus":[],"appointments":[{"appointment":"Professor,Genetics"}],"primaryAppointment":"Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4100&type=small&showNoImage","displayName":"Michele Calos","firstName":"Michele","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Michele_Calos","researchInterest":"My lab is developing novel vectors and strategies for gene and cell therapy.  We are focused on creating and using plasmid DNA vectors that integrate into the genome in a sequence-specific manner.  We are developing innovative gene and cell therapies for genetic diseases such as hemophilia and muscular dystrophy, including approaches involving stem cells."}]}