{"result":[{"lastName":"Sudhof","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Professor (By courtesy),Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Psychiatry & Behavioral Science"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8533&type=small&showNoImage","displayName":"Thomas Sudhof","firstName":"Thomas","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Thomas_Sudhof","researchInterest":"Information transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice."},{"lastName":"Malenka","clinicalFocus":[],"appointments":[{"appointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS"}],"primaryAppointment":"Professor,Psychiatry & Behavioral Science - Psychiatry/Neuroscience/MSLS","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4670&type=small&showNoImage","displayName":"Robert Malenka","firstName":"Robert","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Robert_Malenka","researchInterest":"Long-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy."},{"lastName":"Tsien","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4189&type=small&showNoImage","displayName":"Richard Tsien","firstName":"Richard","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Richard_Tsien","researchInterest":"We study synaptic communication between brain cells with the goal of understanding neuronal computations and memory mechanisms. Main areas of focus include: presynaptic calcium channels, mechanisms of vesicular fusion and recycling. Modulation of synaptic strength through changes in postsynaptic receptors and dendritic morphology. Signaling that links synaptic activity to nuclear transcription and local protein translation. Techniques include imaging, electrophysiology, molecular biology."},{"lastName":"Huguenard","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"},{"appointment":"Professor (By courtesy),Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4124&type=small&showNoImage","displayName":"John Huguenard","firstName":"John","href":"http://med.stanford.edu/profiles/neuroscience/researcher/John_Huguenard","researchInterest":"We are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks."},{"lastName":"Madison","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Associate Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4321&type=small&showNoImage","displayName":"Daniel V. Madison","firstName":"Vernon","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Vernon_Madison","researchInterest":"Our laboratory uses electrophysiological techniques to study the mechanisms of synaptic transmission and plasticity in the mammalian hippocampus. One of the main focuses in the lab is in the study of synaptic long-term potentiation (LTP). LTP is the persistent increase in synaptic strength that occurs after a period of heavy activity in a synaptic connection. It is the most widely studied and compelling model for mechanisms underlying memory formation in the mammalian central nervous system."},{"lastName":"Pang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9396&type=small&showNoImage","displayName":"Zhiping Pang","firstName":"Zhiping","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Zhiping_Pang","researchInterest":""},{"lastName":"Prince","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4531&type=small&showNoImage","displayName":"David Prince","firstName":"David","href":"http://med.stanford.edu/profiles/neuroscience/researcher/David_Prince","researchInterest":"Experiments examine \r\n1)intrinsic properties of neuronal membranes; actions of neurotransmitters that regulate neocortical and thalamic excitability\r\n2) chronic epileptogenesis following cortical injury; changes in intracortical connectivity and receptors; \r\n3) effects of early injury and activity on cortical development/maldevelopment Electrophysiological, anatomical and pharmacological techniques employed.\r\n4. prophylaxis of postraumatic epilepsy\r\n5. Neocortical interneuronal function/modulation"},{"lastName":"de Lecea","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Sleep Center"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Sleep Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7308&type=small&showNoImage","displayName":"Luis de Lecea","firstName":"Luis","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Luis_de Lecea","researchInterest":"Our group initially identified the hypocretins, two hypothalamic neuropeptides that have a key role in maintaining the states of vigilance. We also discovered cortistatin, a peptide that modulates cortical excitability. My lab uses molecular, pharmacological, anatomical and behavioral methods to identify new roles for these transmitters. We are also interested in the cellular and molecular mechanisms by which neuronal systems integrate homeostatic information and regulate complex behaviors."},{"lastName":"MacIver","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor (Research),Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4009&type=small&showNoImage","displayName":"M Bruce MacIver","firstName":"M","href":"http://med.stanford.edu/profiles/neuroscience/researcher/M_MacIver","researchInterest":"We study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices."},{"lastName":"Deisseroth","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Assistant Professor,Bioengineering"},{"appointment":"Associate Professor,Bioengineering"},{"appointment":"Associate Professor,Psychiatry & Behavioral Science"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6080&type=small&showNoImage","displayName":"Karl Deisseroth","firstName":"Karl","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Karl_Deisseroth","researchInterest":"Research in Dr. Deisseroth's laboratory focuses on developing optical, molecular and cellular tools to observe, perturb, and re-engineer brain circuits. His laboratory is based in the James H. Clark Center at Stanford and has developed optogenetic and tissue engineering methods, employing techniques spanning electrophysiology, molecular biology, optics, neural activity imaging, animal behavior, and computational neural network modeling."},{"lastName":"Mysore","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9400&type=small&showNoImage","displayName":"Shreesh P. Mysore","firstName":"Shreesh","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Shreesh_Mysore","researchInterest":"We are constantly faced with a complex sensory environment containing numerous stimuli. However, at each instant, only a small subset of this information filters through to working memory and captures our attention. A key component of this filter is competitive selection, i.e., the selection of the most salient stimulus. With electrophysiology, I study the mechanisms of bottom-up and top-down competitive stimulus selection in the barn owl optic tectum (avian homolog of the superior colliculus)."},{"lastName":"Elias","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pathology"}],"primaryAppointment":"Postdoctoral Research fellow, Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10593&type=small&showNoImage","displayName":"Laura AB Elias","firstName":"Laura","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Laura_Elias","researchInterest":""},{"lastName":"Scott","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4165&type=small&showNoImage","displayName":"Matthew Scott","firstName":"Matthew","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Matthew_Scott","researchInterest":"Genetic regulation of animal development and human disease. We use mice and flies to study Hedgehog/Patched signaling and its links to brain cancer, development of the neural tube and cerebellum, planar cell polarity genes, a neurodegenerative disease called Niemann-Pick syndrome that affects intracellular organelle movements, chromatin proteins in embryonic stem cells, and genetic control of body size."},{"lastName":"Goddard","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8925&type=small&showNoImage","displayName":"Carson Goddard","firstName":"Carson","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Carson_Goddard","researchInterest":""},{"lastName":"Yizhar","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9452&type=small&showNoImage","displayName":"Ofer Yizhar","firstName":"Ofer","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Ofer_Yizhar","researchInterest":""},{"lastName":"Fuller","clinicalFocus":[],"appointments":[{"appointment":"Professor,Developmental Biology"},{"appointment":"Professor,Genetics"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Developmental Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4159&type=small&showNoImage","displayName":"Margaret T. Fuller","firstName":"Margaret","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Margaret_Fuller","researchInterest":"Regulation of stem cell division and self-renewal Cell type specific transcription machinery and regulation of cell differentiation Developmental regulation of cell cycle progression during male meiosis Molecular dissection of the mechanism of cytokinesis."},{"lastName":"Hestrin","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Comparative Medicine"}],"primaryAppointment":"Associate Professor,Comparative Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4343&type=small&showNoImage","displayName":"Shaul Hestrin","firstName":"Shaul","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Shaul_Hestrin","researchInterest":"The main interest of my lab is to understand how the properties of neocortical neurons and the circuits they form give rise to cortical activity and function. Our approach includes recordings from multiple cells, calcium imaging, two-photon imaging and viral-based optogenetic methods to activate  cortical neurons as well as cortical afferents."},{"lastName":"McConnell","clinicalFocus":[],"appointments":[{"appointment":"Member,Bio-X"}],"primaryAppointment":"Member,Bio-X","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5928&type=small&showNoImage","displayName":"Susan McConnell","firstName":"Susan","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Susan_McConnell","researchInterest":"The McConnell Lab studies the cellular and molecular mechanisms that underlie the development of the mammalian cerebral cortex.  Our work focuses on the earliest events that pattern the developing forebrain, enable neural progenitors to divide asymmetrically to generate young neurons, propel the migration of postmitotic neurons outward into their final positions, and sculpt the fates and phenotypes of the neurons as they differentiate."},{"lastName":"Weis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Structural Biology"},{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Cancer Center"}],"primaryAppointment":"Professor,Structural Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4259&type=small&showNoImage","displayName":"William Weis","firstName":"William","href":"http://med.stanford.edu/profiles/neuroscience/researcher/William_Weis","researchInterest":"Our laboratory studies molecular interactions that underlie the establishment and maintenance of cell and tissue structure.  Our specific areas of interest are the targeted delivery of proteins to intracellular membranes, the architecture and dynamics of intercellular adhesion junctions, and signaling pathways that govern cell fate determination.  We also have a long-standing interest in carbohydrate-based cellular recognition and adhesion."},{"lastName":"Luo","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Professor (By courtesy),Neurobiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6229&type=small&showNoImage","displayName":"Liqun Luo","firstName":"Liqun","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Liqun_Luo","researchInterest":"We are studying how neural circuits are assembled during development, and how they contribute to sensory perception.  We are addressing these questions at different levels from molecular, cellular, circuit to animal behavior.  We are primarily using Drosophila as a model organism for our studies.  Most recently, we are also developing novel genetic tools in the mouse to extend our studies to the mammalian brain."},{"lastName":"Kaiser","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10008&type=small&showNoImage","displayName":"Stephen Kaiser","firstName":"Stephen","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Stephen_Kaiser","researchInterest":""},{"lastName":"Sohal","clinicalFocus":[{"focus":"Psychiatry"}],"appointments":[{"appointment":"Instructor,Psychiatry & Behavioral Science - Psychopharmacology"}],"primaryAppointment":"Instructor,Psychiatry & Behavioral Science - Psychopharmacology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10396&type=small&showNoImage","displayName":"Vikaas Sohal","firstName":"Vikaas","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Vikaas_Sohal","researchInterest":""},{"lastName":"Lu","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3976&type=small&showNoImage","displayName":"Bingwei Lu","firstName":"Bingwei","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Bingwei_Lu","researchInterest":"We are interested in understanding how neural stem cells balance their self-renewal and differentiation and how deregulation of this process can result in brain tumor. We are also interested in mechanisms of neurodegeneration in Alzheimer\u0092s and Parkinson\u0092s diseases. We are using both Drosophila and mammalian models to address these fundamental questions."},{"lastName":"Tobin","clinicalFocus":[],"appointments":[{"appointment":"Member,Cancer Center"},{"appointment":"Sr Research Scholar (PI Waiver),Center for Biomedical Ethics"}],"primaryAppointment":"Member,Cancer Center","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6945&type=small&showNoImage","displayName":"Sara L. (Sally) Tobin","firstName":"Sara","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Sara_Tobin","researchInterest":"Tobin is a Senior Research Scholar in the Program for Genomics, Ethics, and Society at the Stanford Center for Biomedical Ethics. She obtained her Ph.D. in Developmental Biology from the University of Washington and did postdoctoral research in Genetics at the University of California, Berkeley and in Biochemistry at the University of California, San Francisco. She became a faculty member at the University of Oklahoma College of Medicine in 1983, where she established her independent research l"},{"lastName":"Nimmerjahn","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)"}],"primaryAppointment":"Postdoctoral Research fellow, Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8659&type=small&showNoImage","displayName":"Axel Nimmerjahn","firstName":"Axel","href":"http://med.stanford.edu/profiles/neuroscience/researcher/Axel_Nimmerjahn","researchInterest":""}]}