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Corinna Darian-Smith
Email:
Profile: http://med.stanford.edu/profiles/Corinna_Darian-Smith/
Alternate Contact: Academic Appointments
Appointment
Organization
Associate Professor
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Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
PhD
University of Melbourne
Neuroscience
1991
Research Interests
My research focuses on two main areas:
1) the structural organization and function of central neural pathways (e.g. of the spinal cord, brainstem, thalamus and cortex) that underlie directed manual behavior, and
2) the capacity of these central neural pathways (circuits) to compensate/adapt following localized injury. Our laboratory uses neuroanatomical, electrophysiological and behavioural approaches to look at the sensorimotor systems of nonhuman primates, and to examine the neural basis for functional 'recovery’ observed following the selective disruption of pathways mediating fine finger control.
We are also interested in the presence and role of adult neurogenesis in the CNS following injury.
1) the structural organization and function of central neural pathways (e.g. of the spinal cord, brainstem, thalamus and cortex) that underlie directed manual behavior, and
2) the capacity of these central neural pathways (circuits) to compensate/adapt following localized injury. Our laboratory uses neuroanatomical, electrophysiological and behavioural approaches to look at the sensorimotor systems of nonhuman primates, and to examine the neural basis for functional 'recovery’ observed following the selective disruption of pathways mediating fine finger control.
We are also interested in the presence and role of adult neurogenesis in the CNS following injury.
Publications
- von der Ohe CG, Garner CC, Darian-Smith C, Heller HC "Synaptic protein dynamics in hibernation." J Neurosci 2007; 27: 1: 84-92 More »
- Darian-Smith C, "Monkey models of recovery of voluntary hand movement after spinal cord and dorsal root injury." ILAR J 2007; 48: 4: 396-410 More »
- Vessal M, Aycock A, Garton MT, Ciferri M, Darian-Smith C "Adult neurogenesis in primate and rodent spinal cord: comparing a cervical dorsal rhizotomy with a dorsal column transection." Eur J Neurosci 2007; 26: 10: 2777-2794 More »
- Darian-Smith C, Ciferri M "Cuneate nucleus reorganization following cervical dorsal rhizotomy in the macaque monkey: Its role in the recovery of manual dexterity." J Comp Neurol 2006; 498: 4: 552-565 More »
- von der Ohe CG, Darian-Smith C, Garner CC, Heller HC "Ubiquitous and temperature-dependent neural plasticity in hibernators." J Neurosci 2006; 26: 41: 10590-8 More »
22 publications: view full list
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