Stanford School of Medicine
Neuroscience Institute at Stanford–

William  C. Mobley, MD, PhD

Email:
Phone:(650) 723-6424
Profile: http://med.stanford.edu/profiles/William_Mobley/
Academic Appointments
Appointment
Organization
Professor
Neurology & Neurological Sciences
Professor
Pediatrics
Professor (By courtesy)
Neurosurgery
Member
Bio-X
Graduate & Fellowship Program Affiliations
Neurosciences ;
 
Honors & Awards
Title
Organization
Date(s)
Fellow
Royal College of Physicians
2001
Cotzias Award
American Academy of Neurology
2004
Member, Institute of Medicine, National Academy of Sciences
National Academy of Sciences
2004
Administrative Appointments
Title
Organization
Start Year
End Year
Chair
Stanford University School of Medicine - Neurology & Neurological Sciences
2004
-
Director, Neuroscience Institute
Stanford University School of Medicine
2003
-
Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
M.D.
Stanford University
Medicine
1976
Ph.D.
Stanford University
Neuro- & Behavioral Science
1974
Postdoctoral Advisees
Heather Brown, Michael Maloney, Rachel Nosheny, Ke Zhan
Web Site Links
Research/Lab website:   Research Lab
Research Interests

Advances in understanding neurotrophic factors and their signaling pathways have provided insights into normal growth, survival and differentiation of neurons. Stimulated by neuropathological and genetic discoveries, studies in cell and animal models of neurodegenerative disorders have begun to clarify pathogenetic mechanisms of disease. My lab examines the intersection of these research themes, and identifies potential mechanisms for linking failed neurotrophin signaling to neurodegeneration.

Publications
  • Chial HJ, Wu R, Ustach CV, McPhail LC, Mobley WC, Chen YQ "Membrane Targeting by APPL1 and APPL2: Dynamic Scaffolds that Oligomerize and Bind Phosphoinositides." Traffic 2008; 9: 2: 215-229 More »
  • Belichenko NP, Belichenko PV, Li HH, Mobley WC, Francke U "Comparative study of brain morphology in Mecp2 mutant mouse models of Rett syndrome." J Comp Neurol 2008; 508: 1: 184-195 More »
  • Liu JJ, Ding J, Wu C, Bhagavatula P, Cui B, Chu S, Mobley WC, Yang Y "Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport." Proc Natl Acad Sci U S A 2007; 104: 7: 2223-8 More »
  • Belichenko PV, Kleschevnikov AM, Salehi A, Epstein CJ, Mobley WC "Synaptic and cognitive abnormalities in mouse models of down syndrome: Exploring genotype-phenotype relationships." J Comp Neurol 2007; 504: 4: 329-345 More »
  • Wu C, Ramirez A, Cui B, Ding J, Delcroix JD, Valletta JS, Liu JJ, Yang Y, Chu S, Mobley WC "A Functional Dynein-Microtubule Network Is Required for NGF Signaling Through the Rap1/MAPK Pathway." Traffic 2007; More »
27 publications:   view full list

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