Helen Bronte-Stewart

Clinical Focus

• Neurology

Professional Education

Postdoctoral Advisees

Julie Nantel, Camille deSolages

Graduate & Fellowship Program Affiliations

• Neurosciences
• Neurosurgery
• Bioengineering

Research Interests

My research focus is human motor control and brain pathophysiology in movement disorders. Our overall goal is to understand the role of the basal ganglia electrical activity in the pathogenesis of movement disorders. We have developed novel computerized technology to measure fine, limb and postural movement. With these we are measuring local field potentials in basal ganglia nuclei in patients with Parkinson's disease and dystonian and correlating brain signalling with motor behavior.

Clinical Trials

• Safety and Efficacy Study of GAD Gene Transfer Therapy in Parkinson's disease Recruiting

Publications

• Quantitative lateralized measures of bradykinesia at different stages of Parkinson's disease: the role of the less affected side. Louie S, Koop MM, Frenklach A, Bronte-Stewart H. Mov Disord. 2009; 24 (13): 1991-7
• Excessive postural sway and the risk of falls at different stages of Parkinson's disease. Frenklach A, Louie S, Koop MM, Bronte-Stewart H. Mov Disord. 2009; 24 (3): 377-85
• The STN beta-band profile in Parkinson's disease is stationary and shows prolonged attenuation after deep brain stimulation. Bronte-Stewart H, Barberini C, Koop MM, Hill BC, Henderson JM, Wingeier B. Exp Neurol. 2009; 215 (1): 20-8
• Hybrid cars may interfere with implanted deep brain stimulators. Chen C, Cole W, Bronte-Stewart HM. Mov Disord. 2009
• Quantitative measures of fine motor, limb, and postural bradykinesia in very early stage, untreated Parkinson's disease. Koop MM, Shivitz N, Brontë-Stewart H. Mov Disord. 2008; 23 (9): 1262-8