{"result":[{"lastName":"Hoehne","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=12461&type=small&showNoImage","displayName":"Aileen Hoehne","firstName":"Aileen","href":"http://med.stanford.edu/profiles/Aileen_Hoehne","researchInterest":""},{"lastName":"Giaccia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Obstetrics & Gynecology"},{"appointment":"Professor (By courtesy),Surgery"}],"primaryAppointment":"Professor,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4141&type=small&showNoImage","displayName":"Amato J. Giaccia","firstName":"Amato","href":"http://med.stanford.edu/profiles/Amato_Giaccia","researchInterest":"During the last five years, we have identified several small molecules that kill VHL deficient renal cancer cells through a synthetic lethal screening approach. Another major interest of my laboratory is in identifying hypoxia-induced genes involved in invasion and metastases. We are also investigating how hypoxia regulates gene expression epigenetically."},{"lastName":"Ronald","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13095&type=small&showNoImage","displayName":"John Ronald","firstName":"John","href":"http://med.stanford.edu/profiles/John_Ronald","researchInterest":"Development of novel gene expression systems for potent, tumor-specific gene therapy of cancer, and to link therapeutic gene expression with imaging reporter gene expression in order to longitudinally track treatment efficacy in living subjects using bioluminescence imaging and positron emission tomography.  Emphasis has also been on labeling therapeutic cells with imaging probes or reporter genes to track the fate of these cells in both small animal models and human subjects."},{"lastName":"Gambhir","clinicalFocus":[{"focus":"Nuclear Medicine"},{"focus":"Radiology"},{"focus":"PET Scan"}],"appointments":[{"appointment":"Professor,Radiology - Diagnostic Radiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor (By courtesy),Bioengineering"},{"appointment":"Professor (By courtesy),Materials Science and Engineering - Engineering Materials Science"}],"primaryAppointment":"Professor,Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3971&type=small&showNoImage","displayName":"Sanjiv Sam Gambhir, MD, PhD","firstName":"Sanjiv","href":"http://med.stanford.edu/profiles/Sanjiv_Gambhir","researchInterest":"My laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the new field of molecular imaging. Methods to image gene expression in living subjects have been developed.  Newer approaches to image fundamental cellular events with optical and radiolabeled probes are under active investigation. These imaging approaches are expected to have a fundamental impact in the study of cancer biology,  as well as in molecular therapeutics including gene therapy"},{"lastName":"Solow-Cordero","clinicalFocus":[],"appointments":[{"appointment":"Director, HTBC,Chemical and Systems Biology"},{"appointment":"Science & Engineering Assoc,Chemical and Systems Biology"}],"primaryAppointment":"Director, HTBC,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=27225&type=small&showNoImage","displayName":"David Solow-Cordero","firstName":"David","href":"http://med.stanford.edu/profiles/David_Solow-Cordero","researchInterest":""},{"lastName":"Cheng","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology"}],"primaryAppointment":"Assistant Professor (Research),Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8291&type=small&showNoImage","displayName":"Zhen Cheng","firstName":"Zhen","href":"http://med.stanford.edu/profiles/Zhen_Cheng","researchInterest":"To develop novel molecular imaging probes and techniques for non-invasively early detection of cancer using multimodality imaging technologies including PET, SPECT, MRI, optical imaging, etc."},{"lastName":"Lutz","clinicalFocus":[{"focus":"Diagnostic Radiology"},{"focus":"Musculoskeletal Radiology"},{"focus":"Body Imaging"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Radiology - Diagnostic Radiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor - Med Center Line,Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8960&type=small&showNoImage","displayName":"Amelie Lutz","firstName":"Amelie","href":"http://med.stanford.edu/profiles/Amelie_Lutz","researchInterest":"Molecular imaging in oncology\r\nCellular imaging of musculoskeletal inflammatory diseases\r\nKinematic musculoskeletal imaging\r\nMagnetic resonance imaging of hepatic disorders"},{"lastName":"Doyle","clinicalFocus":[],"appointments":[{"appointment":"Senior Research Scientist,Pediatrics - Neonatal and Developmental Medicine"}],"primaryAppointment":"Senior Research Scientist,Pediatrics - Neonatal and Developmental Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=25856&type=small&showNoImage","displayName":"Timothy Doyle","firstName":"Timothy","href":"http://med.stanford.edu/profiles/Timothy_Doyle","researchInterest":""},{"lastName":"Miao","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10306&type=small&showNoImage","displayName":"Zheng Miao","firstName":"Zheng","href":"http://med.stanford.edu/profiles/Zheng_Miao","researchInterest":""},{"lastName":"Sheikh","clinicalFocus":[{"focus":"Cardiothoracic Surgery and Transplantation"},{"focus":"Mechanical Circulatory Support"},{"focus":"General Surgery"}],"appointments":[{"appointment":"Clinical Instructor,Cardiothoracic Surgery - Adult Cardiac Surgery"}],"primaryAppointment":"Clinical Instructor,Cardiothoracic Surgery - Adult Cardiac Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35536&type=small&showNoImage","displayName":"Ahmad Sheikh","firstName":"Ahmad","href":"http://med.stanford.edu/profiles/Ahmad_Sheikh","researchInterest":"Molecular imaging of cardiac stem cell therapy\r\nHeart failure\r\nCardiothoracic Transplantation\r\nSurgical Education"},{"lastName":"Daldrup-Link","clinicalFocus":[{"focus":"Radiology"},{"focus":"Pediatric Radiology"},{"focus":"Pediatric Oncology Imaging"}],"appointments":[{"appointment":"Associate Professor,Radiology - Pediatric Radiology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Radiology - Pediatric Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=18936&type=small&showNoImage","displayName":"Heike Daldrup-Link","firstName":"Heike","href":"http://med.stanford.edu/profiles/Heike_Daldrup-Link","researchInterest":"Our Research Group develops non-invasive cellular imaging techniques that can generate detailed information about specific cell populations in the body. The ultimate goal of this research is to determine tumor characteristics which are linked to poor prognosis, to develop, direct and monitor related targeted therapies and to monitor stem cell therapies that regenerate physiologic cell populations. We have a strong focus on translational, bench-to-bedside research."},{"lastName":"Zavaleta","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Radiology - Diagnostic Radiology"}],"primaryAppointment":"Instructor,Radiology - Diagnostic Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9606&type=small&showNoImage","displayName":"Cristina Zavaleta","firstName":"Cristina","href":"http://med.stanford.edu/profiles/Cristina_Zavaleta","researchInterest":"Biomedical Engineering and Nanotechnology with a focus on Raman Spectroscopy and Early Cancer Detection"},{"lastName":"Connolly","clinicalFocus":[{"focus":"Anatomic Pathology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6324&type=small&showNoImage","displayName":"Andrew J. Connolly","firstName":"Andrew","href":"http://med.stanford.edu/profiles/Andrew_Connolly","researchInterest":"My research interests are vascular biology and cardiovascular pathology.  We are currently working on gene expression in endothelial cells at sites of pathology."},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Lin","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stanford Cancer Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Stanford Cancer Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=21152&type=small&showNoImage","displayName":"Yuan Lin","firstName":"Yuan","href":"http://med.stanford.edu/profiles/Yuan_Lin","researchInterest":""},{"lastName":"Rankin","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Radiation Oncology - Radiation and Cancer Biology"}],"primaryAppointment":"Basic Life Science Research Associate,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10065&type=small&showNoImage","displayName":"Erinn Rankin","firstName":"Erinn","href":"http://med.stanford.edu/profiles/Erinn_Rankin","researchInterest":""},{"lastName":"Egeler","clinicalFocus":[],"appointments":[{"appointment":"Spark Program Assistant,Dean's Office - Senior Associate Dean for Research"},{"appointment":"Admin Services Administrator,Dean's Office - Senior Associate Dean for Research"}],"primaryAppointment":"Spark Program Assistant,Dean's Office - Senior Associate Dean for Research","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=19534&type=small&showNoImage","displayName":"Emily Egeler","firstName":"Emily","href":"http://med.stanford.edu/profiles/Emily_Egeler","researchInterest":"Understanding how cells sense and target misfolded proteins for degradation, with the goal of identifying more quality control mechanisms in the cell."},{"lastName":"Boxer","clinicalFocus":[{"focus":"Hematology"},{"focus":"Multiple Myeloma"},{"focus":"Multiple Myeloma - Medical Oncology"},{"focus":"Plasmacytoma"},{"focus":"Plasmacytoma - Hematology"},{"focus":"Plasmacytoma - Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4658&type=small&showNoImage","displayName":"Linda Boxer","firstName":"Linda","href":"http://med.stanford.edu/profiles/Linda_Boxer","researchInterest":"Regulation of expression of oncogenes in normal and malignant hematologic cells."},{"lastName":"Kuo","clinicalFocus":[{"focus":"Medical Oncology"}],"appointments":[{"appointment":"Professor,Medicine - Hematology"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Professor (By courtesy),Chemical and Systems Biology"}],"primaryAppointment":"Professor,Medicine - Hematology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5906&type=small&showNoImage","displayName":"Calvin Kuo","firstName":"Calvin","href":"http://med.stanford.edu/profiles/Calvin_Kuo","researchInterest":"We explore angiogenesis, cancer genomics, intestinal stem cells, and hepatic glucose metabolism.  Angiogenesis projects include endothelial miRNA and GPCR ko mice, blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy.  Intestinal stem cell projects use primary intestinal culture and mouse genetics to study injury-inducible vs homeostatic stem cells.  We use primary organoid cultures of diverse tissues for oncogene functional screening and therapeutics discovery."},{"lastName":"Cochran","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Bioengineering"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"},{"appointment":"Associate Professor (By courtesy),Chemical Engineering"}],"primaryAppointment":"Associate Professor,Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6393&type=small&showNoImage","displayName":"Jennifer R. Cochran","firstName":"Jennifer","href":"http://med.stanford.edu/profiles/Jennifer_Cochran","researchInterest":"Molecular Bioengineering, Protein Biochemistry and Biotechnology, Cell and Tissue Engineering, Molecular Imaging"},{"lastName":"Wong","clinicalFocus":[],"appointments":[{"appointment":"Professor,Neurosurgery"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Neurosurgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7143&type=small&showNoImage","displayName":"Albert J. Wong, M.D.","firstName":"Albert","href":"http://med.stanford.edu/profiles/Albert_Wong","researchInterest":"Our goal is to define targets for cancer therapeutics by identifying alterations in signal transduction proteins. We first identified a naturally occurring  mutant EGF receptor (EGFRvIII) and then delineated its unique signal transduction pathway. This work led to the identification of Gab1 followed by the discovery that JNK is constitutively active in tumors. We intiated using altered proteins as the target for vaccination, where an EGFRvIII based vaccine appears to be highly effective."},{"lastName":"James","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9971&type=small&showNoImage","displayName":"Michelle L. James","firstName":"Michelle","href":"http://med.stanford.edu/profiles/Michelle_James","researchInterest":"My research is focused on developing and evaluating molecular imaging agents for visualizing neurological diseases in living subjects."},{"lastName":"Brown","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Emeritus Faculty, Acad Council,Radiation Oncology - Radiation and Cancer Biology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor Emeritus,Radiation Oncology - Radiation and Cancer Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4536&type=small&showNoImage","displayName":"Martin Brown","firstName":"Martin","href":"http://med.stanford.edu/profiles/Martin_Brown","researchInterest":"We seek to understand the mechanisms responsible for the resistance of cancers to treatment and to develop strategies to overcome these resistances. We are using molecular and cellular techniques and mouse models to potentiate the activity of radiation on tumors by inhibiting the bone marrow rescue of the tumor vasculature following therapy."},{"lastName":"Roth","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4175&type=small&showNoImage","displayName":"Richard Roth","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Roth","researchInterest":"Insulin is one of the primary regulators of rapid anabolic responses in the body. Defects in the synthesis and/or ability of cells to respond to insulin results in the condition known as diabetes mellitus. To better design methods of treatment for this disorder, we have been focusing our research on how insulin elicits its various biological responses."},{"lastName":"Chung","clinicalFocus":[],"appointments":[{"appointment":"Basic Life Science Research Associate,Obstetrics & Gynecology"}],"primaryAppointment":"Basic Life Science Research Associate,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10387&type=small&showNoImage","displayName":"Young Min Chung","firstName":"Young Min","href":"http://med.stanford.edu/profiles/Young Min_Chung","researchInterest":""}]}