MIPS Molecular Imaging Program at Stanford

Heike Daldrup-Link

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Publication Details

  • Detection of postoperative granulation tissue with an ICG-enhanced integrated OI-/X-ray System.

    Meier R, Boddington S, Krug C, Acosta FL, Thullier D, Henning TD, Sutton EJ, Tavri S, Lotz JC, Daldrup-Link HE. J Transl Med. 2008: 6 73

    The development of postoperative granulation tissue is one of the main postoperative risks after lumbar spine surgery. This granulation tissue may lead to persistent or new clinical symptoms or complicate a follow up surgery. A sensitive non-invasive imaging technique, that could diagnose this granulation tissue at the bedside, would help to develop appropriate treatments. Thus, the purpose of this study was to establish a fast and economic imaging tool for the diagnosis of granulation tissue after lumbar spine surgery, using a new integrated Optical Imaging (OI)/X-ray imaging system and the FDA-approved fluorescent contrast agent Indocyanine Green (ICG).

    PubMedID: 19038047

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