MIPS Molecular Imaging Program at Stanford

Dominique Van de Sompel

Publication Details

  • Simultaneous reconstruction and registration algorithm for limited view transmission tomography using a multiple cluster approximation to the joint histogram with an anatomical prior.

    Van de Sompel D, Brady M. Conf Proc IEEE Eng Med Biol Soc. 2009: 2009 5733-6

    We develop a novel simultaneous reconstruction and registration algorithm for limited view transmission tomography. We derive a cost function using Bayesian probability theory, and propose a similarity metric based on the explicit modeling of the joint histogram as a sum of bivariate clusters. The resulting algorithm shows a robust mitigation of the data insufficiency problem in limited view tomography. To our knowledge, our work represents the first attempt to incorporate non-registered, multimodal anatomical priors into limited view transmission tomography by using joint histogram based similarity measures.

    PubMedID: 19963646

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