Sandip Biswal, MD

Publication Details

• Continuous infusion of UHMWPE particles induces increased bone macrophages and osteolysis.

  Ren PG, Irani A, Huang Z, Ma T, Biswal S, Goodman SB. Clin Orthop Relat Res. 2011; 469 (1): 113-22

  Aseptic loosening and periprosthetic osteolysis resulting from wear debris are major complications of total joint arthroplasty. Monocyte/macrophages are the key cells related to osteolysis at the bone-implant interface of joint arthroplasties. Whether the monocyte/macrophages found at the implant interface in the presence of polyethylene particles are locally or systemically derived is unknown.

  PubMedID: 21042895