MIPS Molecular Imaging Program at Stanford

Joseph C. Wu

Publication Details

  • Limitations of dobutamine for enhancing flow heterogeneity in the presence of single coronary stenosis: implications for technetium-99m-sestamibi imaging.

    Wu JC, Yun JJ, Heller EN, Dione DP, DeMan P, Liu YH, Zaret BL, Wackers FJ, Sinusas AJ. J Nucl Med. 1998; 39 (3): 417-25

    Dobutamine is used as an alternative to exercise in conjunction with 99mTc-sestamibi SPECT perfusion imaging for detection of coronary artery disease. However, the use of quantitative dobutamine 99mTc-sestamibi SPECT imaging for enhanced detection of coronary stenosis has not been established. The goal of this study is to examine the effects of dobutamine stress on regional myocardial blood flow and relative myocardial 99mTc-sestamibi activity in the presence of a single-vessel stenosis.

    PubMedID: 9529285

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