MIPS Molecular Imaging Program at Stanford

Daniel Spielman

Publication Details

  • Temporal lobe magnetic resonance spectroscopic imaging following selective amygdalohippocampectomy for treatment-resistant epilepsy.

    Spencer DC, Szumowski J, Kraemer DF, Wang PY, Burchiel KJ, Spielman DM. Acta Neurol Scand. 2005; 112 (1): 6-12

    Magnetic resonance spectroscopic imaging (MRSI) may show circumscribed or extensive decreased brain N-acetyl aspartate (NAA)/creatine and phosphocreatine (Cr) in epilepsy patients. We compared temporal lobe MRSI in patients seizure-free (SzF) or with persistent seizures (PSz) following selective amygdalohippocampectomy (SAH) for medically intractable mesial temporal lobe epilepsy (mTLE). We hypothesized that PSz patients had more extensive temporal lobe metabolite abnormalities than SzF patients.

    PubMedID: 15932349

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