MIPS Molecular Imaging Program at Stanford

Lawrence "Rusty" Hofmann, MD

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Publication Details

  • Constitutively active HIF-1alpha improves perfusion and arterial remodeling in an endovascular model of limb ischemia.

    Patel TH, Kimura H, Weiss CR, Semenza GL, Hofmann LV. Cardiovasc Res. 2005; 68 (1): 144-54

    Hypoxia-inducible factor 1 (HIF-1) regulates the expression of angiogenic growth factors. We analyzed the effect of intramuscular (i.m.) delivery of AdCA5, an adenovirus encoding a constitutively active form of the HIF-1alpha subunit, in a novel model of limb ischemia.

    PubMedID: 15921668

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