Sanjiv Sam Gambhir, MD, PhD

Publication Details

• Protein-functionalized synthetic antiferromagnetic nanoparticles for biomolecule detection and magnetic manipulation.

  Fu A, Hu W, Xu L, Wilson RJ, Yu H, Osterfeld SJ, Gambhir SS, Wang SX. Angew Chem Int Ed Engl. 2009; 48 (9): 1620-4

  Direct protein functionalization provides synthetic antiferromagnetic nanoparticles with high chemical specificity and multifunctionality. These nanoparticle-protein conjugates function as improved magnetic labels for biological detection experiments, and exhibit tunable responses to a small external magnetic field gradient, thus allowing the observation of distinctive single nanoparticle motion.

  PubMedID: 19156803