Publications
-
"Picolog," a synthetically-available bryostatin analog, inhibits growth of MYC-induced lymphoma in vivo.
DeChristopher BA,
Fan AC, Felsher DW, Wender PA.
Oncotarget.
2012;
3
(1):
58-66
-
Beyond Cell Penetrating Peptides: Designed Molecular Transporters.
Wender PA,
Cooley CB, Geihe EI.
Drug Discov Today Technol.
2012;
9
(1):
e49-e55
-
Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells.
Geihe EI,
Cooley CB, Simon JR, Kiesewetter MK, Edward JA, Hickerson RP, Kaspar RL, Hedrick JL, Waymouth RM, Wender PA.
Proc Natl Acad Sci U S A.
2012;
109
(33):
13171-6
-
Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro.
DeChristopher BA,
Loy BA, Marsden MD, Schrier AJ, Zack JA, Wender PA.
Nat Chem.
2012;
4
(9):
705-10
-
Rhodium dinaphthocyclooctatetraene complexes: synthesis, characterization and catalytic activity in [5+2] cycloadditions.
Wender PA,
Lesser AB, Sirois LE.
Angew Chem Int Ed Engl.
2012;
51
(11):
2736-40
-
Taxol-oligoarginine conjugates overcome drug resistance in-vitro in human ovarian carcinoma.
Wender PA,
Galliher WC, Bhat NM, Pillow TH, Bieber MM, Teng NN.
Gynecol Oncol.
2012;
126
(1):
118-23
-
Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivity.
Wender PA,
Baryza JL, Brenner SE, DeChristopher BA, Loy BA, Schrier AJ, Verma VA.
Proc Natl Acad Sci U S A.
2011;
108
(17):
6721-6
-
Function Oriented Synthesis: Preparation and Initial Biological Evaluation of New A-Ring-Modified Bryologs.
Wender PA,
Reuber J.
Tetrahedron.
2011;
67
(51):
9998-10005
-
Gateway synthesis of daphnane congeners and their protein kinase C affinities and cell-growth activities.
Wender PA,
Buschmann N, Cardin NB, Jones LR, Kan C, Kee JM, Kowalski JA, Longcore KE.
Nat Chem.
2011;
3
(8):
615-9
-
Total synthesis of bryostatin 9.
Wender PA,
Schrier AJ.
J Am Chem Soc.
2011;
133
(24):
9228-31
-
A metal-catalyzed intermolecular [5+2] cycloaddition/Nazarov cyclization sequence and cascade.
Wender PA,
Stemmler RT, Sirois LE.
J Am Chem Soc.
2010;
132
(8):
2532-3
-
Electronic and steric control of regioselectivities in Rh(I)-catalyzed (5 + 2) cycloadditions: experiment and theory.
Liu P,
Sirois LE, Cheong PH, Yu ZX, Hartung IV, Rieck H, Wender PA, Houk KN.
J Am Chem Soc.
2010;
132
(29):
10127-35
-
Highly efficient, facile, room temperature intermolecular [5 + 2] cycloadditions catalyzed by cationic rhodium(I): one step to cycloheptenes and their libraries.
Wender PA,
Sirois LE, Stemmler RT, Williams TJ.
Org Lett.
2010;
12
(7):
1604-7
-
An approach to the site-selective diversification of apoptolidin A with peptide-based catalysts.
Lewis CA,
Longcore KE, Miller SJ, Wender PA.
J Nat Prod.
2009;
72
(10):
1864-9
-
Apoptolidins E and F, new glycosylated macrolactones isolated from Nocardiopsis sp.
Wender PA,
Longcore KE.
Org Lett.
2009;
11
(23):
5474-7
-
Cyclocarboamination of alkynes with aziridines: synthesis of 2,3-dihydropyrroles by a catalyzed formal [3 + 2] cycloaddition.
Wender PA,
Strand D.
J Am Chem Soc.
2009;
131
(22):
7528-9
-
Oligocarbonate molecular transporters: oligomerization-based syntheses and cell-penetrating studies.
Cooley CB,
Trantow BM, Nederberg F, Kiesewetter MK, Hedrick JL, Waymouth RM, Wender PA.
J Am Chem Soc.
2009;
131
(45):
16401-3
-
Synthesis at the molecular frontier.
Wender PA,
Miller BL.
Nature.
2009;
460
(7252):
197-201
-
The synthesis of highly substituted cyclooctatetraene scaffolds by metal-catalyzed [2+2+2+2] cycloadditions: studies on regioselectivity, dynamic properties, and metal chelation.
Wender PA,
Christy JP, Lesser AB, Gieseler MT.
Angew Chem Int Ed Engl.
2009;
48
(41):
7687-90
-
Function-oriented synthesis: biological evaluation of laulimalide analogues derived from a last step cross metathesis diversification strategy.
Mooberry SL,
Hilinski MK, Clark EA, Wender PA.
Mol Pharm.
2008 Sep-Oct;
5
(5):
829-38
-
Efficient synthetic access to a new family of highly potent bryostatin analogues via a Prins-driven macrocyclization strategy.
Wender PA,
Dechristopher BA, Schrier AJ.
J Am Chem Soc.
2008;
130
(21):
6658-9
-
Function-oriented synthesis, step economy, and drug design.
Wender PA,
Verma VA, Paxton TJ, Pillow TH.
Acc Chem Res.
2008;
41
(1):
40-9
-
Origins of differences in reactivities of alkenes, alkynes, and allenes in [Rh(CO)2Cl]2-catalyzed (5 + 2) cycloaddition reactions with vinylcyclopropanes.
Yu ZX,
Cheong PH, Liu P, Legault CY, Wender PA, Houk KN.
J Am Chem Soc.
2008;
130
(8):
2378-9
-
Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters.
Dubikovskaya EA,
Thorne SH, Pillow TH, Contag CH, Wender PA.
Proc Natl Acad Sci U S A.
2008;
105
(34):
12128-33
-
Practical synthesis of prostratin, DPP, and their analogs, adjuvant leads against latent HIV.
Wender PA,
Kee JM, Warrington JM.
Science.
2008;
320
(5876):
649-52
-
Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells.
Lee HL,
Dubikovskaya EA, Hwang H, Semyonov AN, Wang H, Jones LR, Twieg RJ, Moerner WE, Wender PA.
J Am Chem Soc.
2008;
130
(29):
9364-70
-
The design of guanidinium-rich transporters and their internalization mechanisms.
Wender PA,
Galliher WC, Goun EA, Jones LR, Pillow TH.
Adv Drug Deliv Rev.
2008;
60
(4-5):
452-72
-
The design, synthesis, and evaluation of C7 diversified bryostatin analogs reveals a hot spot for PKC affinity.
Wender PA,
Verma VA.
Org Lett.
2008;
10
(15):
3331-4
-
A computationally designed Rh(I)-catalyzed two-component [5+2+1] cycloaddition of ene-vinylcyclopropanes and CO for the synthesis of cyclooctenones.
Wang Y,
Wang J, Su J, Huang F, Jiao L, Liang Y, Yang D, Zhang S, Wender PA, Yu ZX.
J Am Chem Soc.
2007;
129
(33):
10060-1
-
Function-oriented synthesis: studies aimed at the synthesis and mode of action of 1alpha-alkyldaphnane analogues.
Wender PA,
D'Angelo N, Elitzin VI, Ernst M, Jackson-Ugueto EE, Kowalski JA, McKendry S, Rehfeuter M, Sun R, Voigtlaender D.
Org Lett.
2007;
9
(9):
1829-32
-
Isolation, structure determination, and anti-cancer activity of apoptolidin D.
Wender PA,
Longcore KE.
Org Lett.
2007;
9
(4):
691-4
-
Nickel(0)-catalyzed [2 + 2 + 2 + 2] cycloadditions of terminal diynes for the synthesis of substituted cyclooctatetraenes.
Wender PA,
Christy JP.
J Am Chem Soc.
2007;
129
(44):
13402-3
-
Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice.
Wender PA,
Goun EA, Jones LR, Pillow TH, Rothbard JB, Shinde R, Contag CH.
Proc Natl Acad Sci U S A.
2007;
104
(25):
10340-5
-
Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation.
Goun EA,
Shinde R, Dehnert KW, Adams-Bond A, Wender PA, Contag CH, Franc BL.
Bioconjug Chem.
2006 May-Jun;
17
(3):
787-96
-
Laulimalide and synthetic laulimalide analogues are synergistic with paclitaxel and 2-methoxyestradiol.
Clark EA,
Hills PM, Davidson BS, Wender PA, Mooberry SL.
Mol Pharm.
2006 Jul-Aug;
3
(4):
457-67
-
Asymmetric catalysis of the [5 + 2] cycloaddition reaction of vinylcyclopropanes and pi-systems.
Wender PA,
Haustedt LO, Lim J, Love JA, Williams TJ, Yoon JY.
J Am Chem Soc.
2006;
128
(19):
6302-3
-
Correlation of F0F1-ATPase inhibition and antiproliferative activity of apoptolidin analogues.
Wender PA,
Jankowski OD, Longcore K, Tabet EA, Seto H, Tomikawa T.
Org Lett.
2006;
8
(4):
589-92
-
Cyclopentadienone synthesis by rhodium(I)-catalyzed [3 + 2] cycloaddition reactions of cyclopropenones and alkynes.
Wender PA,
Paxton TJ, Williams TJ.
J Am Chem Soc.
2006;
128
(46):
14814-5
-
Design, synthesis, and biological evaluation of a potent, PKC selective, B-ring analog of bryostatin.
Wender PA,
Verma VA.
Org Lett.
2006;
8
(9):
1893-6
-
Metal-catalyzed [2+2+1] cycloadditions of 1,3-dienes, allenes, and CO.
Wender PA,
Croatt MP, Deschamps NM.
Angew Chem Int Ed Engl.
2006;
45
(15):
2459-62
-
Molecular transporters: synthesis of oligoguanidinium transporters and their application to drug delivery and real-time imaging.
Goun EA,
Pillow TH, Jones LR, Rothbard JB, Wender PA.
Chembiochem.
2006;
7
(10):
1497-515
-
Pharmacophore mapping in the laulimalide series: total synthesis of a vinylogue for a late-stage metathesis diversification strategy.
Wender PA,
Hilinski MK, Skaanderup PR, Soldermann NG, Mooberry SL.
Org Lett.
2006;
8
(18):
4105-8
-
Releasable luciferin-transporter conjugates: tools for the real-time analysis of cellular uptake and release.
Jones LR,
Goun EA, Shinde R, Rothbard JB, Contag CH, Wender PA.
J Am Chem Soc.
2006;
128
(20):
6526-7
-
RhI-catalyzed C-C bond activation: seven-membered ring synthesis by a [6+1] carbonylative ring-expansion reaction of allenylcyclobutanes.
Wender PA,
Deschamps NM, Sun R.
Angew Chem Int Ed Engl.
2006;
45
(24):
3957-60
-
Rhodium(I)-catalyzed [4+2+2] cycloadditions of 1,3-dienes, alkenes, and alkynes for the synthesis of cyclooctadienes.
Wender PA,
Christy JP.
J Am Chem Soc.
2006;
128
(16):
5354-5
-
Studies on oxidopyrylium [5+2] cycloadditions: toward a general synthetic route to the C12-hydroxydaphnetoxins.
Wender PA,
Bi FC, Buschmann N, Gosselin F, Kan C, Kee JM, Ohmura H.
Org Lett.
2006;
8
(23):
5373-6
-
Synthesis and PKC binding of a new class of a-ring diversifiable bryostatin analogues utilizing a double asymmetric hydrogenation and cross-coupling strategy.
Wender PA,
Horan JC.
Org Lett.
2006;
8
(20):
4581-4
-
Total synthesis and biological evaluation of 11-desmethyllaulimalide, a highly potent simplified laulimalide analogue.
Wender PA,
Hilinski MK, Soldermann N, Mooberry SL.
Org Lett.
2006;
8
(7):
1507-10
-
Total synthesis and initial biological evaluation of new B-ring-modified bryostatin analogs.
Wender PA,
Horan JC, Verma VA.
Org Lett.
2006;
8
(23):
5299-302
-
Adaptive translocation: the role of hydrogen bonding and membrane potential in the uptake of guanidinium-rich transporters into cells.
Rothbard JB,
Jessop TC, Wender PA.
Adv Drug Deliv Rev.
2005;
57
(4):
495-504
-
Apoptolidins B and C: isolation, structure determination, and biological activity.
Wender PA,
Sukopp M, Longcore K.
Org Lett.
2005;
7
(14):
3025-8
-
Dendrimeric molecular transporters: synthesis and evaluation of tunable polyguanidino dendrimers that facilitate cellular uptake.
Wender PA,
Kreider E, Pelkey ET, Rothbard J, Vandeusen CL.
Org Lett.
2005;
7
(22):
4815-8
-
Identification of a tunable site in bryostatin analogs: C20 Bryologs through late stage diversification.
Wender PA,
Baryza JL.
Org Lett.
2005;
7
(6):
1177-80
-
Late-stage intermolecular CH activation for lead diversification: a highly chemoselective oxyfunctionalization of the C-9 position of potent bryostatin analogues.
Wender PA,
Hilinski MK, Mayweg AV.
Org Lett.
2005;
7
(1):
79-82
-
Multicomponent cycloadditions: the four-component [5+1+2+1] cycloaddition of vinylcyclopropanes, alkynes, and CO.
Wender PA,
Gamber GG, Hubbard RD, Pham SM, Zhang L.
J Am Chem Soc.
2005;
127
(9):
2836-7
-
Role of the A-ring of bryostatin analogues in PKC binding: synthesis and initial biological evaluation of new A-ring-modified bryologs.
Wender PA,
Clarke MO, Horan JC.
Org Lett.
2005;
7
(10):
1995-8
-
Transition metal-catalyzed intermolecular [5+2] and [5+2+1] cycloadditions of allenes and vinylcyclopropanes.
Wegner HA,
de Meijere A, Wender PA.
J Am Chem Soc.
2005;
127
(18):
6530-1
-
Function oriented synthesis: the design, synthesis, PKC binding and translocation activity of a new bryostatin analog.
Wender PA,
Baryza JL, Brenner SE, Clarke MO, Craske ML, Horan JC, Meyer T.
Curr Drug Discov Technol.
2004;
1
(1):
1-11
-
Intermolecular dienyl Pauson-Khand reaction.
Wender PA,
Deschamps NM, Williams TJ.
Angew Chem Int Ed Engl.
2004;
43
(23):
3076-9
-
Nanotube molecular transporters: internalization of carbon nanotube-protein conjugates into Mammalian cells.
Shi Kam NW,
Jessop TC, Wender PA, Dai H.
J Am Chem Soc.
2004;
126
(22):
6850-1
-
Rhodium(I)-catalyzed [2+2+1] cycloadditions of 1,3-dienes, alkenes, and CO.
Wender PA,
Croatt MP, Deschamps NM.
J Am Chem Soc.
2004;
126
(19):
5948-9
-
Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells.
Rothbard JB,
Jessop TC, Lewis RS, Murray BA, Wender PA.
J Am Chem Soc.
2004;
126
(31):
9506-7
-
Simplified analogs of bryostatin with anticancer activity display greater potency for translocation of PKCdelta-GFP.
Baryza JL,
Brenner SE, Craske ML, Meyer T, Wender PA.
Chem Biol.
2004;
11
(9):
1261-7
-
A concise, selective synthesis of the polyketide spacer domain of a potent bryostatin analogue.
Wender PA,
Mayweg AV, VanDeusen CL.
Org Lett.
2003;
5
(3):
277-9
-
A new synthetic approach to the C ring of known as well as novel bryostatin analogues.
Wender PA,
Koehler MF, Sendzik M.
Org Lett.
2003;
5
(24):
4549-52
-
Facile synthetic access to and biological evaluation of the macrocyclic core of apoptolidin.
Wender PA,
Jankowski OD, Tabet EA, Seto H.
Org Lett.
2003;
5
(13):
2299-302
-
Guanidinium rich peptide transporters and drug delivery.
Wright LR,
Rothbard JB, Wender PA.
Curr Protein Pept Sci.
2003;
4
(2):
105-24
-
Photoinduced cleavage of DNA by bromofluoroacetophenone-pyrrolecarboxamide conjugates.
Wender PA,
Jeon R.
Bioorg Med Chem Lett.
2003;
13
(10):
1763-6
-
Synthesis and biological evaluation of (-)-laulimalide analogues.
Wender PA,
Hegde SG, Hubbard RD, Zhang L, Mooberry SL.
Org Lett.
2003;
5
(19):
3507-9
-
The dienyl Pauson-Khand reaction.
Wender PA,
Deschamps NM, Gamber GG.
Angew Chem Int Ed Engl.
2003;
42
(16):
1853-7
-
Toward a structure-activity relationship for apoptolidin: selective functionalization of the hydroxyl group array.
Wender PA,
Jankowski OD, Tabet EA, Seto H.
Org Lett.
2003;
5
(4):
487-90
-
Isoapoptolidin: structure and activity of the ring-expanded isomer of apoptolidin.
Wender PA,
Gulledge AV, Jankowski OD, Seto H.
Org Lett.
2002;
4
(22):
3819-22
-
Oligocarbamate molecular transporters: design, synthesis, and biological evaluation of a new class of transporters for drug delivery.
Wender PA,
Rothbard JB, Jessop TC, Kreider EL, Wylie BL.
J Am Chem Soc.
2002;
124
(45):
13382-3
-
The practical synthesis of a novel and highly potent analogue of bryostatin.
Wender PA,
Baryza JL, Bennett CE, Bi FC, Brenner SE, Clarke MO, Horan JC, Kan C, Lacôte E, Lippa B, Nell PG, Turner TM.
J Am Chem Soc.
2002;
124
(46):
13648-9
-
Three-component cycloadditions: the first transition metal-catalyzed [5+2+1] cycloaddition reactions.
Wender PA,
Gamber GG, Hubbard RD, Zhang L.
J Am Chem Soc.
2002;
124
(12):
2876-7
-
Total synthesis of (-)-laulimalide.
Wender PA,
Hegde SG, Hubbard RD, Zhang L.
J Am Chem Soc.
2002;
124
(18):
4956-7
-
Transition metal-catalyzed hetero-[5 + 2] cycloadditions of cyclopropyl imines and alkynes: dihydroazepines from simple, readily available starting materials.
Wender PA,
Pedersen TM, Scanio MJ.
J Am Chem Soc.
2002;
124
(51):
15154-5
-
[(arene)Rh(cod)]+ Complexes as catalysts for [5+2] cycloaddition reactions.
Wender PA,
Williams TJ.
Angew Chem Int Ed Engl.
2002;
41
(23):
4550-3
-
An efficient, scalable synthesis of the molecular transporter octaarginine via a segment doubling strategy.
Wender PA,
Jessop TC, Pattabiraman K, Pelkey ET, VanDeusen CL.
Org Lett.
2001;
3
(21):
3229-32
-
Asymmetric synthesis of the tricyclic core of NGF-inducing cyathane diterpenes via a transition-metal-catalyzed [5 + 2] cycloaddition.
Wender PA,
Bi FC, Brodney MA, Gosselin F.
Org Lett.
2001;
3
(13):
2105-8
-
Molecular transporters for peptides: delivery of a cardioprotective epsilonPKC agonist peptide into cells and intact ischemic heart using a transport system, R(7).
Chen L,
Wright LR, Chen CH, Oliver SF, Wender PA, Mochly-Rosen D.
Chem Biol.
2001;
8
(12):
1123-9
-
Serial [5+2]/[4+2] Cycloadditions: Facile, Preparative, Multi-Component Syntheses of Polycyclic Compounds from Simple, Readily Available Starting Materials This research was supported by grant CHE-9800445 from the National Science Foundation. The Stanford Graduate Fellowship (M.J.C.S. and G.G.G.) is gratefully acknowledged.
Wender PA,
Gamber GG, Scanio MJ.
Angew Chem Int Ed Engl.
2001;
40
(20):
3895-3897
-
The first intermolecular transition metal-catalyzed [5+2] cycloadditions with simple, unactivated, vinylcyclopropanes.
Wender PA,
Barzilay CM, Dyckman AJ.
J Am Chem Soc.
2001;
123
(1):
179-80
-
A new and practical five-carbon component for metal-catalyzed
Wender PA,
Dyckman AJ, Husfeld CO, Scanio MJ.
Org Lett.
2000;
2
(11):
1609-11
-
Asymmetric total synthesis of (+)-aphanamol I based on the transition metal catalyzed [5 + 2] cycloaddition of allenes and vinylcyclopropanes.
Wender PA,
Zhang L.
Org Lett.
2000;
2
(15):
2323-6
-
Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation.
Rothbard JB,
Garlington S, Lin Q, Kirschberg T, Kreider E, McGrane PL, Wender PA, Khavari PA.
Nat Med.
2000;
6
(11):
1253-7
-
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters.
Wender PA,
Mitchell DJ, Pattabiraman K, Pelkey ET, Steinman L, Rothbard JB.
Proc Natl Acad Sci U S A.
2000;
97
(24):
13003-8
-
A new class of simplified phorbol ester analogues: synthesis and binding to PKC and eta PKC-C1B (eta PKC-CRD2).
Wender PA,
Kirschberg TA, Williams PD, Bastiaans HM, Irie K.
Org Lett.
1999;
1
(7):
1009-12
-
Bromoacetophenone-based photonucleases: photoinduced cleavage of DNA by 4'-bromoacetophenone-pyrrolecarboxamide conjugates.
Wender PA,
Jeon R.
Org Lett.
1999;
1
(13):
2117-20
-
Selective binding of bryostatin analogues to the cysteine rich domains of protein kinase C isozymes.
Wender PA,
Lippa B, Park CM, Irie K, Nakahara A, Ohigashi H.
Bioorg Med Chem Lett.
1999;
9
(12):
1687-90
-
The rational design of potential chemotherapeutic agents: synthesis of bryostatin analogues.
Wender PA,
Hinkle KW, Koehler MF, Lippa B.
Med Res Rev.
1999;
19
(5):
388-407
-
The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1.
Wender PA,
DeBrabander J, Harran PG, Jimenez JM, Koehler MF, Lippa B, Park CM, Siedenbiedel C, Pettit GR.
Proc Natl Acad Sci U S A.
1998;
95
(12):
6624-9
-
Sequence-specific DNA cleavage by conjugates ofbenzotriazoles and minor groove binders.
Wender PA.,
Touami SM, Poon CC,.
JACS.
1997;
(119):
7611-7612.
-
The first formal asymmetric synthesis of phorbol.
Wender PA,
Rice KD, Schnute ME..
JACS.
1997;
(119):
7987-7898
-
The first synthesis of a daphnane diterpene: the enantiocontrolled total synthesis of (+)-resiniferatoxin.
Wender PA,
Jesudason CD, Nakahira H, Tamura N, Tebbe AL, Ueno Y..
JACS.
1997;
(119):
12976-12977.
-
The pinene path to taxanes .6. A concise stereocontrolled synthesis of taxol.
Wender PA,
Badham NF, Conway SP, Floreancig PE, Glass TE, Houze JB, Krauss NE, Lee DS, Marquess DG, McGrane PL, Meng W..
JACS.
1997;
(119):
2757-2758.
-
Introduction: Frontiers in Organic Synthesis.
Wender PA,
Chem Rev.
1996;
96
(1):
1-2
-
The Pinene Path to Taxanes. 4. Approaches to Taxol and Taxol Analogs through Elaboration of Aromatic C-Ring Precursors.
Wender PA,
Glass TE, Krauss NE, Mühlebach M, Peschke B, Rawlins DB.
J Org Chem.
1996;
61
(22):
7662-7663
-
Identification, activity, and structural studies of peptides incorporating the phorbol ester-binding domain of protein kinase C.
Wender PA,
Irie K, Miller BL.
Proc Natl Acad Sci U S A.
1995;
92
(1):
239-43
-
Studies on DNA-cleaving agents: computer modeling analysis of the mechanism of activation and cleavage of dynemicin-oligonucleotide complexes.
Wender PA,
Kelly RC, Beckham S, Miller BL.
Proc Natl Acad Sci U S A.
1991;
88
(19):
8835-9
-
Modeling of the bryostatins to the phorbol ester pharmacophore on protein kinase C.
Wender PA,
Cribbs CM, Koehler KF, Sharkey NA, Herald CL, Kamano Y, Pettit GR, Blumberg PM.
Proc Natl Acad Sci U S A.
1988;
85
(19):
7197-201
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