Peter Jackson

Publications

• A high-content cellular senescence screen identifies candidate tumor suppressors, including EPHA3. Lahtela J, Corson LB, Hemmes A, Brauer MJ, Koopal S, Lee J, Hunsaker TL, Jackson PK, Verschuren EW. Cell Cycle. 2013; 12 (4): 625-34
• Alkylsulfanyl-1,2,4-triazoles, a new class of allosteric valosine containing protein inhibitors. Synthesis and structure-activity relationships. Polucci P, Magnaghi P, Angiolini M, Asa D, Avanzi N, Badari A, Bertrand J, Casale E, Cauteruccio S, Cirla A, Cozzi L, Galvani A, Jackson PK, Liu Y, Magnuson S, Malgesini B, Nuvoloni S, Orrenius C, Sirtori FR, Riceputi L, Rizzi S, Trucchi B, O'Brien T, Isacchi A, Donati D, D'Alessio R. J Med Chem. 2013; 56 (2): 437-50
• Cilia, tubby mice, and obesity. Mukhopadhyay S, Jackson PK. Cilia. 2013; 2 (1): 1
• Our thanks to Cilia's reviewers. Beales P, Jackson PK. Cilia. 2013; 2 (1): 4
• The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Mukhopadhyay S, Wen X, Ratti N, Loktev A, Rangell L, Scales SJ, Jackson PK. Cell. 2013; 152 (1-2): 210-23
• Cilia - the prodigal organelle. Beales P, Jackson PK. Cilia. 2012; 1 (1): 1
• Cilia develop long-lasting contacts, with other cilia. Jackson PK, Cilia. 2012; 1 (1): 5
• Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity. Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, Skelton NJ, Fauber BP, Pan B, Malek S, Stokoe D, Ludlam MJ, Bowman KK, Wu J, Giannetti AM, Starovasnik MA, Mellman I, Jackson PK, Rudolph J, Wang W, Fang G. Proc Natl Acad Sci U S A. 2012; 109 (14): 5299-304
• TTBK2 kinase: linking primary cilia and cerebellar ataxias. Jackson PK, Cell. 2012; 151 (4): 697-9
• A novel acetylation of β-tubulin by San modulates microtubule polymerization via down-regulating tubulin incorporation. Chu CW, Hou F, Zhang J, Phu L, Loktev AV, Kirkpatrick DS, Jackson PK, Zhao Y, Zou H. Mol Biol Cell. 2011; 22 (4): 448-56
• An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium. Wright KJ, Baye LM, Olivier-Mason A, Mukhopadhyay S, Sang L, Kwong M, Wang W, Pretorius PR, Sheffield VC, Sengupta P, Slusarski DC, Jackson PK. Genes Dev. 2011; 25 (22): 2347-60
• Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry. Huang X, Summers MK, Pham V, Lill JR, Liu J, Lee G, Kirkpatrick DS, Jackson PK, Fang G, Dixit VM. Mol Cell. 2011; 42 (4): 511-23
• Do cilia put brakes on the cell cycle? Jackson PK, Nat Cell Biol. 2011; 13 (4): 340-2
• Live-cell microscopy reveals small molecule inhibitor effects on MAPK pathway dynamics. Anderson DJ, Durieux JK, Song K, Alvarado R, Jackson PK, Hatzivassiliou G, Ludlam MJ. PLoS One. 2011; 6 (8): e22607
• Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Sang L, Miller JJ, Corbit KC, Giles RH, Brauer MJ, Otto EA, Baye LM, Wen X, Scales SJ, Kwong M, Huntzicker EG, Sfakianos MK, Sandoval W, Bazan JF, Kulkarni P, Garcia-Gonzalo FR, Seol AD, O'Toole JF, Held S, Reutter HM, Lane WS, Rafiq MA, Noor A, Ansar M, Devi AR, Sheffield VC, Slusarski DC, Vincent JB, Doherty DA, Hildebrandt F, Reiter JF, Jackson PK. Cell. 2011; 145 (4): 513-28
• Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome. Westlake CJ, Baye LM, Nachury MV, Wright KJ, Ervin KE, Phu L, Chalouni C, Beck JS, Kirkpatrick DS, Slusarski DC, Sheffield VC, Scheller RH, Jackson PK. Proc Natl Acad Sci U S A. 2011; 108 (7): 2759-64
• Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7. Wertz IE, Kusam S, Lam C, Okamoto T, Sandoval W, Anderson DJ, Helgason E, Ernst JA, Eby M, Liu J, Belmont LD, Kaminker JS, O'Rourke KM, Pujara K, Kohli PB, Johnson AR, Chiu ML, Lill JR, Jackson PK, Fairbrother WJ, Seshagiri S, Ludlam MJ, Leong KG, Dueber EC, Maecker H, Huang DC, Dixit VM. Nature. 2011; 471 (7336): 110-4
• The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly. Torres JZ, Summers MK, Peterson D, Brauer MJ, Lee J, Senese S, Gholkar AA, Lo YC, Lei X, Jung K, Anderson DC, Davis DP, Belmont L, Jackson PK. Cell. 2011; 147 (6): 1309-23
• The tubby family proteins. Mukhopadhyay S, Jackson PK. Genome Biol. 2011; 12 (6): 225
• A chemosensitization screen identifies TP53RK, a kinase that restrains apoptosis after mitotic stress. Peterson D, Lee J, Lei XC, Forrest WF, Davis DP, Jackson PK, Belmont LD. Cancer Res. 2010; 70 (15): 6325-35
• A specific form of phospho protein phosphatase 2 regulates anaphase-promoting complex/cyclosome association with spindle poles. Torres JZ, Ban KH, Jackson PK. Mol Biol Cell. 2010; 21 (6): 897-904
• APC/C(Cdc20) targets E2F1 for degradation in prometaphase. Peart MJ, Poyurovsky MV, Kass EM, Urist M, Verschuren EW, Summers MK, Jackson PK, Prives C. Cell Cycle. 2010; 9 (19): 3956-64
• Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy. Otto EA, Hurd TW, Airik R, Chaki M, Zhou W, Stoetzel C, Patil SB, Levy S, Ghosh AK, Murga-Zamalloa CA, van Reeuwijk J, Letteboer SJ, Sang L, Giles RH, Liu Q, Coene KL, Estrada-Cuzcano A, Collin RW, McLaughlin HM, Held S, Kasanuki JM, Ramaswami G, Conte J, Lopez I, Washburn J, Macdonald J, Hu J, Yamashita Y, Maher ER, Guay-Woodford LM, Neumann HP, Obermüller N, Koenekoop RK, Bergmann C, Bei X, Lewis RA, Katsanis N, Lopes V, Williams DS, Lyons RH, Dang CV, Brito DA, Dias MB, Zhang X, Cavalcoli JD, Nürnberg G, Nürnberg P, Pierce EA, Jackson PK, Antignac C, Saunier S, Roepman R, Dollfus H, Khanna H, Hildebrandt F. Nat Genet. 2010; 42 (10): 840-50
• Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy. O'Toole JF, Liu Y, Davis EE, Westlake CJ, Attanasio M, Otto EA, Seelow D, Nurnberg G, Becker C, Nuutinen M, Kärppä M, Ignatius J, Uusimaa J, Pakanen S, Jaakkola E, van den Heuvel LP, Fehrenbach H, Wiggins R, Goyal M, Zhou W, Wolf MT, Wise E, Helou J, Allen SJ, Murga-Zamalloa CA, Ashraf S, Chaki M, Heeringa S, Chernin G, Hoskins BE, Chaib H, Gleeson J, Kusakabe T, Suzuki T, Isaac RE, Quarmby LM, Tennant B, Fujioka H, Tuominen H, Hassinen I, Lohi H, van Houten JL, Rotig A, Sayer JA, Rolinski B, Freisinger P, Madhavan SM, Herzer M, Madignier F, Prokisch H, Nurnberg P, Jackson PK, Jackson P, Khanna H, Katsanis N, Hildebrandt F. J Clin Invest. 2010; 120 (3): 791-802
• TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia. Mukhopadhyay S, Wen X, Chih B, Nelson CD, Lane WS, Scales SJ, Jackson PK. Genes Dev. 2010; 24 (19): 2180-93
• Biochemical analysis of the Anaphase Promoting Complex: activities of E2 enzymes and substrate competitive (pseudosubstrate) inhibitors. Summers MK, Jackson PK. Methods Mol Biol. 2009: 545 313-30
• High-throughput generation of tagged stable cell lines for proteomic analysis. Torres JZ, Miller JJ, Jackson PK. Proteomics. 2009; 9 (10): 2888-91
• Navigating the deubiquitinating proteome with a CompPASS. Jackson PK, Cell. 2009; 138 (2): 222-4
• A BBSome subunit links ciliogenesis, microtubule stability, and acetylation. Loktev AV, Zhang Q, Beck JS, Searby CC, Scheetz TE, Bazan JF, Slusarski DC, Sheffield VC, Jackson PK, Nachury MV. Dev Cell. 2008; 15 (6): 854-65
• Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition. Tang W, Wu JQ, Guo Y, Hansen DV, Perry JA, Freel CD, Nutt L, Jackson PK, Kornbluth S. Mol Biol Cell. 2008; 19 (8): 3536-43
• Emi1 protein accumulation implicates misregulation of the anaphase promoting complex/cyclosome pathway in ovarian clear cell carcinoma. Gütgemann I, Lehman NL, Jackson PK, Longacre TA. Mod Pathol. 2008; 21 (4): 445-54
• New ligands for melanocortin receptors. Kaelin CB, Candille SI, Yu B, Jackson P, Thompson DA, Nix MA, Binkley J, Millhauser GL, Barsh GS. Int J Obes (Lond). 2008: 32 Suppl 7 S19-27
• Stopping replication, at the beginning. Jackson PK, Nat Chem Biol. 2008; 4 (6): 331-2
• The hunt for cyclin. Jackson PK, Cell. 2008; 134 (2): 199-202
• The nucleolar phosphatase Cdc14B is dispensable for chromosome segregation and mitotic exit in human cells. Berdougo E, Nachury MV, Jackson PK, Jallepalli PV. Cell Cycle. 2008; 7 (9): 1184-90
• The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC. Summers MK, Pan B, Mukhyala K, Jackson PK. Mol Cell. 2008; 31 (4): 544-56
• A bacterial effector targets Mad2L2, an APC inhibitor, to modulate host cell cycling. Iwai H, Kim M, Yoshikawa Y, Ashida H, Ogawa M, Fujita Y, Muller D, Kirikae T, Jackson PK, Kotani S, Sasakawa C. Cell. 2007; 130 (4): 611-23
• A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Nachury MV, Loktev AV, Zhang Q, Westlake CJ, Peränen J, Merdes A, Slusarski DC, Scheller RH, Bazan JF, Sheffield VC, Jackson PK. Cell. 2007; 129 (6): 1201-13
• A role for Cdc2- and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest. Wu Q, Guo Y, Yamada A, Perry JA, Wang MZ, Araki M, Freel CD, Tung JJ, Tang W, Margolis SS, Jackson PK, Yamano H, Asano M, Kornbluth S. Curr Biol. 2007; 17 (3): 213-24
• Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. Wu JQ, Hansen DV, Guo Y, Wang MZ, Tang W, Freel CD, Tung JJ, Jackson PK, Kornbluth S. Proc Natl Acad Sci U S A. 2007; 104 (42): 16564-9
• Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1). Keck JM, Summers MK, Tedesco D, Ekholm-Reed S, Chuang LC, Jackson PK, Reed SI. J Cell Biol. 2007; 178 (3): 371-85
• Emi2 at the crossroads: where CSF meets MPF. Hansen DV, Pomerening JR, Summers MK, Miller JJ, Ferrell JE, Jackson PK. Cell Cycle. 2007; 6 (6): 732-8
• Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene. Westlake CJ, Junutula JR, Simon GC, Pilli M, Prekeris R, Scheller RH, Jackson PK, Eldridge AG. Proc Natl Acad Sci U S A. 2007; 104 (4): 1236-41
• Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence. Verschuren EW, Ban KH, Masek MA, Lehman NL, Jackson PK. Mol Cell Biol. 2007; 27 (22): 7955-65
• Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors. Lehman NL, Tibshirani R, Hsu JY, Natkunam Y, Harris BT, West RB, Masek MA, Montgomery K, van de Rijn M, Jackson PK. Am J Pathol. 2007; 170 (5): 1793-805
• Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1). Marangos P, Verschuren EW, Chen R, Jackson PK, Carroll J. J Cell Biol. 2007; 176 (1): 65-75
• Putting transcription repression and protein destruction in pRb's pocket. Verschuren EW, Jackson PK. Dev Cell. 2007; 12 (2): 169-70
• The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis. Ban KH, Torres JZ, Miller JJ, Mikhailov A, Nachury MV, Tung JJ, Rieder CL, Jackson PK. Dev Cell. 2007; 13 (1): 29-42
• Translational unmasking of Emi2 directs cytostatic factor arrest in meiosis II. Tung JJ, Padmanabhan K, Hansen DV, Richter JD, Jackson PK. Cell Cycle. 2007; 6 (6): 725-31
• CaMKII and polo-like kinase 1 sequentially phosphorylate the cytostatic factor Emi2/XErp1 to trigger its destruction and meiotic exit. Hansen DV, Tung JJ, Jackson PK. Proc Natl Acad Sci U S A. 2006; 103 (3): 608-13
• Climbing the Greatwall to mitosis. Jackson PK, Mol Cell. 2006; 22 (2): 156-7
• Developmental neurobiology: a destructive switch for neurons. Jackson PK, Nature. 2006; 442 (7101): 365-6
• Dual degradation signals control Gli protein stability and tumor formation. Huntzicker EG, Estay IS, Zhen H, Lokteva LA, Jackson PK, Oro AE. Genes Dev. 2006; 20 (3): 276-81
• Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor. Miller JJ, Summers MK, Hansen DV, Nachury MV, Lehman NL, Loktev A, Jackson PK. Genes Dev. 2006; 20 (17): 2410-20
• Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis. Madgwick S, Hansen DV, Levasseur M, Jackson PK, Jones KT. J Cell Biol. 2006; 174 (6): 791-801
• Overexpression of the anaphase promoting complex/cyclosome inhibitor Emi1 leads to tetraploidy and genomic instability of p53-deficient cells. Lehman NL, Verschuren EW, Hsu JY, Cherry AM, Jackson PK. Cell Cycle. 2006; 5 (14): 1569-73
• The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1. Eldridge AG, Loktev AV, Hansen DV, Verschuren EW, Reimann JD, Jackson PK. Cell. 2006; 124 (2): 367-80
• A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs. Tung JJ, Hansen DV, Ban KH, Loktev AV, Summers MK, Adler JR, Jackson PK. Proc Natl Acad Sci U S A. 2005; 102 (12): 4318-23
• Emi1 class of proteins regulate entry into meiosis and the meiosis I to meiosis II transition in Xenopus oocytes. Tung JJ, Jackson PK. Cell Cycle. 2005; 4 (3): 478-82
• Inhibition of the anaphase-promoting complex by the Xnf7 ubiquitin ligase. Casaletto JB, Nutt LK, Wu Q, Moore JD, Etkin LD, Jackson PK, Hunt T, Kornbluth S. J Cell Biol. 2005; 169 (1): 61-71
• Screening of tissue microarrays for ubiquitin proteasome system components in tumors. Lehman NL, van de Rijn M, Jackson PK. Methods Enzymol. 2005: 399 334-55
• Linking tumor suppression, DNA damage and the anaphase-promoting complex. Jackson PK, Trends Cell Biol. 2004; 14 (7): 331-4
• Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1. Hansen DV, Loktev AV, Ban KH, Jackson PK. Mol Biol Cell. 2004; 15 (12): 5623-34
• Wagging the dogma; tissue-specific cell cycle control in the mouse embryo. Pagano M, Jackson PK. Cell. 2004; 118 (5): 535-8
• Xenopus Cdc14 alpha/beta are localized to the nucleolus and centrosome and are required for embryonic cell division. Kaiser BK, Nachury MV, Gardner BE, Jackson PK. BMC Cell Biol. 2004: 5 27
• Accessory proteins for melanocortin signaling: attractin and mahogunin. He L, Eldridge AG, Jackson PK, Gunn TM, Barsh GS. Ann N Y Acad Sci. 2003: 994 288-98
• Can Fizzy fly solo? Jackson PK, Nat Cell Biol. 2003; 5 (10): 864-5
• Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo. Guardavaccaro D, Kudo Y, Boulaire J, Barchi M, Busino L, Donzelli M, Margottin-Goguet F, Jackson PK, Yamasaki L, Pagano M. Dev Cell. 2003; 4 (6): 799-812
• Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase. Margottin-Goguet F, Hsu JY, Loktev A, Hsieh HM, Reimann JD, Jackson PK. Dev Cell. 2003; 4 (6): 813-26
• Spongiform degeneration in mahoganoid mutant mice. He L, Lu XY, Jolly AF, Eldridge AG, Watson SJ, Jackson PK, Barsh GS, Gunn TM. Science. 2003; 299 (5607): 710-2
• Ubiquitinating a phosphorylated Cdk inhibitor on the blades of the Cdc4 beta-propeller. Jackson PK, Cell. 2003; 112 (2): 142-4
• Control of the centriole and centrosome cycles by ubiquitination enzymes. Hansen DV, Hsu JY, Kaiser BK, Jackson PK, Eldridge AG. Oncogene. 2002; 21 (40): 6209-21
• Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation. Mailand N, Lukas C, Kaiser BK, Jackson PK, Bartek J, Lukas J. Nat Cell Biol. 2002; 4 (4): 317-22
• Disruption of centrosome structure, chromosome segregation, and cytokinesis by misexpression of human Cdc14A phosphatase. Kaiser BK, Zimmerman ZA, Charbonneau H, Jackson PK. Mol Biol Cell. 2002; 13 (7): 2289-300
• E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1). Hsu JY, Reimann JD, Sørensen CS, Lukas J, Jackson PK. Nat Cell Biol. 2002; 4 (5): 358-66
• Emi1 is required for cytostatic factor arrest in vertebrate eggs. Reimann JD, Jackson PK. Nature. 2002; 416 (6883): 850-4
• The E3 ubiquitin ligase GREUL1 anteriorizes ectoderm during Xenopus development. Borchers AG, Hufton AL, Eldridge AG, Jackson PK, Harland RM, Baker JC. Dev Biol. 2002; 251 (2): 395-408
• The SCF ubiquitin ligase: an extended look. Jackson PK, Eldridge AG. Mol Cell. 2002; 9 (5): 923-5
• A new RING for SUMO: wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligases. Jackson PK, Genes Dev. 2001; 15 (23): 3053-8
• Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication. Furstenthal L, Kaiser BK, Swanson C, Jackson PK. J Cell Biol. 2001; 152 (6): 1267-78
• Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Reimann JD, Freed E, Hsu JY, Kramer ER, Peters JM, Jackson PK. Cell. 2001; 105 (5): 645-55
• Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins. Reimann JD, Gardner BE, Margottin-Goguet F, Jackson PK. Genes Dev. 2001; 15 (24): 3278-85
• Triggering ubiquitination of a CDK inhibitor at origins of DNA replication. Furstenthal L, Swanson C, Kaiser BK, Eldridge AG, Jackson PK. Nat Cell Biol. 2001; 3 (8): 715-22
• Nuclear accumulation of cyclin E/Cdk2 triggers a concentration-dependent switch for the destruction of p27Xic1. Swanson C, Ross J, Jackson PK. Proc Natl Acad Sci U S A. 2000; 97 (14): 7796-801
• The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases. Jackson PK, Eldridge AG, Freed E, Furstenthal L, Hsu JY, Kaiser BK, Reimann JD. Trends Cell Biol. 2000; 10 (10): 429-39
• Budding yeast Cdc6p induces re-replication in fission yeast by inhibition of SCF(Pop)-mediated proteolysis. Wolf DA, McKeon F, Jackson PK. Mol Gen Genet. 1999; 262 (3): 473-80
• Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle. Freed E, Lacey KR, Huie P, Lyapina SA, Deshaies RJ, Stearns T, Jackson PK. Genes Dev. 1999; 13 (17): 2242-57
• Cyclin-dependent kinase control of centrosome duplication. Lacey KR, Jackson PK, Stearns T. Proc Natl Acad Sci U S A. 1999; 96 (6): 2817-22
• F-box/WD-repeat proteins pop1p and Sud1p/Pop2p form complexes that bind and direct the proteolysis of cdc18p. Wolf DA, McKeon F, Jackson PK. Curr Biol. 1999; 9 (7): 373-6
• Identification of novel F-box proteins in Xenopus laevis. Regan-Reimann JD, Duong QV, Jackson PK. Curr Biol. 1999; 9 (20): R762-3
• Cell cycle: oiling the gears of anaphase. Wolf DA, Jackson PK. Curr Biol. 1998; 8 (18): R636-9
• Cell cycle: cull and destroy. Jackson PK, Curr Biol. 1996; 6 (10): 1209-12
• The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products. Wen ST, Jackson PK, Van Etten RA. EMBO J. 1996; 15 (7): 1583-95
• Cell cycle arrest by tyrosine kinase Abl involves altered early mitogenic response. Mattioni T, Jackson PK, Bchini-Hooft van Huijsduijnen O, Picard D. Oncogene. 1995; 10 (7): 1325-33
• Early events in DNA replication require cyclin E and are blocked by p21CIP1. Jackson PK, Chevalier S, Philippe M, Kirschner MW. J Cell Biol. 1995; 130 (4): 755-69
• Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Chen J, Jackson PK, Kirschner MW, Dutta A. Nature. 1995; 374 (6520): 386-8
• Mitosis in transition. King RW, Jackson PK, Kirschner MW. Cell. 1994; 79 (4): 563-71
• The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity. Van Etten RA, Jackson PK, Baltimore D, Sanders MC, Matsudaira PT, Janmey PA. J Cell Biol. 1994; 124 (3): 325-40
• Mutation of a phenylalanine conserved in SH3-containing tyrosine kinases activates the transforming ability of c-Abl. Jackson PK, Paskind M, Baltimore D. Oncogene. 1993; 8 (7): 1943-56
• Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line. Daley GQ, Van Etten RA, Jackson PK, Bernards A, Baltimore D. Mol Cell Biol. 1992; 12 (4): 1864-71
• Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo. Mayer BJ, Jackson PK, Van Etten RA, Baltimore D. Mol Cell Biol. 1992; 12 (2): 609-18
• Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Tybulewicz VL, Crawford CE, Jackson PK, Bronson RT, Mulligan RC. Cell. 1991; 65 (7): 1153-63
• The noncatalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine-phosphorylated cellular proteins with high affinity. Mayer BJ, Jackson PK, Baltimore D. Proc Natl Acad Sci U S A. 1991; 88 (2): 627-31