{"result":[{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Pasca","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurobiology"}],"primaryAppointment":"Postdoctoral Research fellow, Neurobiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10793&type=small&showNoImage","displayName":"Sergiu P. Pasca","firstName":"Sergiu","href":"http://med.stanford.edu/profiles/Sergiu_Pasca","researchInterest":"My primary interest is in understanding the molecular and cellular underpinnings of psychiatric diseases of developmental origin, in particular autism spectrum disorders and schizophrenias. I use induced pluripotent stem cells (iPSC) derived from patients to identify cellular phenotypes associated with these diseases. I am also working on developing reliable assays for probing neuronal phenotypes in vitro and optimizing high-throughput drug screening in iPSC-derived neurons from patients."},{"lastName":"Lee-Messer","clinicalFocus":[{"focus":"Neurology - Child Neurology"},{"focus":"Neurology"}],"appointments":[{"appointment":"Clinical Assistant Professor,Neurology & Neurological Sciences"}],"primaryAppointment":"Clinical Assistant Professor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8762&type=small&showNoImage","displayName":"Christopher Lee-Messer","firstName":"Christopher","href":"http://med.stanford.edu/profiles/Christopher_Lee-Messer","researchInterest":"My chief clinical focus is in pediatric epilepsy, especially the relationship between stroke and epilepsy. My translational and basic science interests lie in neuronal development and physiology, and in using that knowledge to create treatments for disease, especially in the injured developing brain.  To investigate these subjects, I am currently participating as a fellow in the Deisseroth lab, combining techniques of in vivo and in vitro electrophysiology with optogenetics."},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Center for Interdisciplinary Brain Sciences Research","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20934&type=small&showNoImage","displayName":"Lu Chen","firstName":"Lu","href":"http://med.stanford.edu/profiles/Lu_Chen","researchInterest":"What distinguishes us humans from other animals is our ability to undergo complex behavior. The synapses are the structural connection between neurons that mediates the communication between neurons, which underlies our various cognitive function. My research program aims to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation."},{"lastName":"Graef","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7247&type=small&showNoImage","displayName":"Isabella Graef","firstName":"Isabella","href":"http://med.stanford.edu/profiles/Isabella_Graef","researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases."},{"lastName":"Lewis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4176&type=small&showNoImage","displayName":"Richard Lewis","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Lewis","researchInterest":"We study molecular mechanisms of calcium signaling with a focus on store-operated CRAC channels and their essential roles in T cell development and function.  Currently we aim to define the molecular mechanism for CRAC channel activation and the means by which calcium signal dynamics mediate specific activation of transcription factors and T-cell genes during development."},{"lastName":"Malmersjoe","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Chemical and Systems Biology"}],"primaryAppointment":"Postdoctoral Research fellow, Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=15963&type=small&showNoImage","displayName":"Seth Malmersjö","firstName":"Carl","href":"http://med.stanford.edu/profiles/Carl_Malmersjoe","researchInterest":""},{"lastName":"Teruel","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=14171&type=small&showNoImage","displayName":"Mary Frances Nunez Teruel","firstName":"Mary","href":"http://med.stanford.edu/profiles/Mary_Teruel","researchInterest":"The Teruel Lab uses a combination of engineering and biological approaches including high-throughput screening of RNAi and DNA construct libraries, targeted mass spectrometry, live-cell fluorescence microscopy, and bioinformatics to investigate the systems biology of cell differentiation and cell signaling with particular focus on uncovering the molecular mechanisms underlying insulin resistance, diabetes, and obesity."},{"lastName":"Butte","clinicalFocus":[{"focus":"Allergy and Immunology"},{"focus":"Pediatric Allergy/Immun"}],"appointments":[{"appointment":"Assistant Professor,Pediatrics - Immunology and Allergy"},{"appointment":"Member,Child Health Research Institute"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pediatrics - Immunology and Allergy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13416&type=small&showNoImage","displayName":"Manish J. Butte, MD PhD","firstName":"Manish","href":"http://med.stanford.edu/profiles/Manish_Butte","researchInterest":"Our laboratory's goal is to address fundamental and therapeutic questions in immunology using innovative nanotechnological and biophysical approaches to visualize and manipulate cells. Our primary focus is on understanding the molecular controls that balance T cell activation versus tolerance. The ultimate aim of our work is to manipulate T cell signaling pathways to control immunologically-mediated diseases."},{"lastName":"Garcia","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Structural Biology"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4370&type=small&showNoImage","displayName":"Chris Garcia","firstName":"Chris","href":"http://med.stanford.edu/profiles/Chris_Garcia","researchInterest":"Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology.  We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches."},{"lastName":"Berndt","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Bioengineering"}],"primaryAppointment":"Postdoctoral Research fellow, Bioengineering","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24149&type=small&showNoImage","displayName":"Andre Berndt","firstName":"Andre","href":"http://med.stanford.edu/profiles/Andre_Berndt","researchInterest":""},{"lastName":"Lin","clinicalFocus":[{"focus":"Cardiovascular Medicine"}],"appointments":[{"appointment":"Clinical Instructor,Medicine - Cardiovascular Medicine"},{"appointment":"Postdoctoral Research fellow, Medicine"}],"primaryAppointment":"Clinical Instructor,Medicine - Cardiovascular Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=23327&type=small&showNoImage","displayName":"Shin Lin","firstName":"Shin","href":"http://med.stanford.edu/profiles/Shin_Lin","researchInterest":""},{"lastName":"Luoma","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24597&type=small&showNoImage","displayName":"Jessie Luoma","firstName":"Jessie","href":"http://med.stanford.edu/profiles/Jessie_Luoma","researchInterest":""},{"lastName":"Bernstein","clinicalFocus":[{"focus":"Autism"},{"focus":"Developmental Disorders"},{"focus":"Cardiovascular Genetics"},{"focus":"Craniofacial Abnormalities"},{"focus":"Craniosynostosis"},{"focus":"Cleft Lip"},{"focus":"Cleft Palate"},{"focus":"Clinical Genetics"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Pediatrics - Medical Genetics"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Assistant Professor - Med Center Line,Pediatrics - Medical Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8523&type=small&showNoImage","displayName":"Jon Bernstein","firstName":"Jonathan","href":"http://med.stanford.edu/profiles/Jonathan_Bernstein","researchInterest":"I am interested in the genetics of autism spectrum and other developmental disorders.   In collaboration with the laboratories of Dr. Ricardo Dolmetsch and Joachim Hallmayer I am working to develop induced pluripotent stem cell (iPSC) models of genetic disorders associated with autism and developmental disability."},{"lastName":"Mullins","clinicalFocus":[{"focus":"Pathology"}],"appointments":[{"appointment":"Instructor,Pathology"}],"primaryAppointment":"Instructor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8576&type=small&showNoImage","displayName":"Franklin Mullins","firstName":"Franklin","href":"http://med.stanford.edu/profiles/Franklin_Mullins","researchInterest":""},{"lastName":"Nguyen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Stanford Cancer Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Stanford Cancer Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24227&type=small&showNoImage","displayName":"Le Xuan Truong Nguyen","firstName":"Le Xuan Truong","href":"http://med.stanford.edu/profiles/Le Xuan Truong_Nguyen","researchInterest":""},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Hestrin","clinicalFocus":[],"appointments":[{"appointment":"Professor,Comparative Medicine"}],"primaryAppointment":"Professor,Comparative Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4343&type=small&showNoImage","displayName":"Shaul Hestrin","firstName":"Shaul","href":"http://med.stanford.edu/profiles/Shaul_Hestrin","researchInterest":"The main interest of my lab is to understand how the properties of neocortical neurons and the circuits they form give rise to cortical activity and function. Our approach includes recordings from multiple cells, calcium imaging, two-photon imaging and viral-based optogenetic methods to activate  cortical neurons as well as cortical afferents."},{"lastName":"Chen","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=20866&type=small&showNoImage","displayName":"Lulu Chen","firstName":"Lulu","href":"http://med.stanford.edu/profiles/Lulu_Chen","researchInterest":""},{"lastName":"Crabtree","clinicalFocus":[],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"},{"appointment":"Professor,Developmental Biology"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4283&type=small&showNoImage","displayName":"Gerald Crabtree","firstName":"Gerald","href":"http://med.stanford.edu/profiles/Gerald_Crabtree","researchInterest":"Chromatin regulation and its roles in human cancer and the development of the nervous system.  Engineering new methods for studying and controlling chromatin in living cells."},{"lastName":"Okada","clinicalFocus":[],"appointments":[{"appointment":"Instructor,Neurology & Neurological Sciences"}],"primaryAppointment":"Instructor,Neurology & Neurological Sciences","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8191&type=small&showNoImage","displayName":"Ami Okada","firstName":"Ami","href":"http://med.stanford.edu/profiles/Ami_Okada","researchInterest":"Our interests are to understand the mechanism and control of signals that regulate proliferation and differentiation in adult tissue.  We are currently focused on studying modulation of the Hedgehog pathway in brain and muscle stem cell compartments during normal homeostasis and in degeneration or disease."},{"lastName":"Lee","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Neurosciences Institute"}],"primaryAppointment":"Postdoctoral Research fellow, Neurosciences Institute","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=29999&type=small&showNoImage","displayName":"SUNGJIN LEE","firstName":"SUNGJIN","href":"http://med.stanford.edu/profiles/SUNGJIN_Lee","researchInterest":""}]}