{"result":[{"lastName":"Fathman","clinicalFocus":[{"focus":"Immunology"},{"focus":"Immunology and Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4479&type=small&showNoImage","displayName":"C. Garrison Fathman","firstName":"C","href":"http://med.stanford.edu/profiles/C_Fathman","researchInterest":"My lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity.   We use lentiviral mediated transduction of murine dendritic cells with immunoregulatory proteins for site specific and targeted immunotherapy. We have identified and characterized a gene (GRAIL) that seems to control T cell anergy.    We have recently characterized a gene (Deaf1) that seems to play a major role in peripheral tolerance in T1D."},{"lastName":"Michie","clinicalFocus":[{"focus":"Anatomic Pathology"},{"focus":"Pathology and Laboratory Medicine"}],"appointments":[{"appointment":"Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4707&type=small&showNoImage","displayName":"Sara Michie","firstName":"Sara","href":"http://med.stanford.edu/profiles/Sara_Michie","researchInterest":"Lymphocyte/endothelial cell adhesion mechanisms involved in lymphocyte migration to sites of inflammation; regulation of expression of endothelial cell adhesion molecules."},{"lastName":"Chi","clinicalFocus":[{"focus":"Internal Medicine"}],"appointments":[{"appointment":"Clinical Assistant Professor,Medicine - General Medical Disciplines"}],"primaryAppointment":"Clinical Assistant Professor,Medicine - General Medical Disciplines","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8566&type=small&showNoImage","displayName":"Jeffrey Chi","firstName":"Jeffrey","href":"http://med.stanford.edu/profiles/Jeffrey_Chi","researchInterest":""},{"lastName":"Huang","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Microbiology & Immunology"}],"primaryAppointment":"Postdoctoral Research fellow, Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13753&type=small&showNoImage","displayName":"Jun Huang","firstName":"Jun","href":"http://med.stanford.edu/profiles/Jun_Huang","researchInterest":""},{"lastName":"Lewis","clinicalFocus":[],"appointments":[{"appointment":"Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4176&type=small&showNoImage","displayName":"Richard Lewis","firstName":"Richard","href":"http://med.stanford.edu/profiles/Richard_Lewis","researchInterest":"We study molecular mechanisms of calcium signaling with a focus on store-operated CRAC channels and their essential roles in T cell development and function.  Currently we aim to define the molecular mechanism for CRAC channel activation and the means by which calcium signal dynamics mediate specific activation of transcription factors and T-cell genes during development."},{"lastName":"Dong","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=25093&type=small&showNoImage","displayName":"Shen Dong","firstName":"Shen","href":"http://med.stanford.edu/profiles/Shen_Dong","researchInterest":""},{"lastName":"Mullins","clinicalFocus":[{"focus":"Pathology"}],"appointments":[{"appointment":"Instructor,Pathology"}],"primaryAppointment":"Instructor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8576&type=small&showNoImage","displayName":"Franklin Mullins","firstName":"Franklin","href":"http://med.stanford.edu/profiles/Franklin_Mullins","researchInterest":""},{"lastName":"Kodama","clinicalFocus":[],"appointments":[{"appointment":"Engr Res Assoc,Pediatrics - Systems Medicine"}],"primaryAppointment":"Engr Res Assoc,Pediatrics - Systems Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=27436&type=small&showNoImage","displayName":"Keiichi Kodama","firstName":"Keiichi","href":"http://med.stanford.edu/profiles/Keiichi_Kodama","researchInterest":""},{"lastName":"Graef","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Pathology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7247&type=small&showNoImage","displayName":"Isabella Graef","firstName":"Isabella","href":"http://med.stanford.edu/profiles/Isabella_Graef","researchInterest":"We are interested in addressing questions in neuronal development and function by a combination of genetic, cell biological, biochemical and chemical approaches. \r\nThe main focus of our lab is centered around two topics: 1) the interface of signaling and gene regulation in neuronal development, with a focus on calcineurin-NFAT signaling; 2) the development of small molecules, which interfere with protein-protein interactions underlying neurodegenerative diseases."},{"lastName":"Aye","clinicalFocus":[{"focus":"Endocrinology/Diabetes, Pediatric"},{"focus":"Pediatric Endocrinology"}],"appointments":[{"appointment":"Assistant Professor - Med Center Line,Pediatrics - Endocrinology and Diabetes"}],"primaryAppointment":"Assistant Professor - Med Center Line,Pediatrics - Endocrinology and Diabetes","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7653&type=small&showNoImage","displayName":"Tandy Aye","firstName":"Tandy","href":"http://med.stanford.edu/profiles/Tandy_Aye","researchInterest":""},{"lastName":"Buckingham","clinicalFocus":[{"focus":"Pediatric Endocrinology"},{"focus":"Type 1 Diabetes Mellitus"}],"appointments":[{"appointment":"Professor - Med Center Line,Pediatrics - Endocrinology and Diabetes"}],"primaryAppointment":"Professor - Med Center Line,Pediatrics - Endocrinology and Diabetes","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4413&type=small&showNoImage","displayName":"Bruce Buckingham","firstName":"Bruce","href":"http://med.stanford.edu/profiles/Bruce_Buckingham","researchInterest":"My major interest is in type 1 diabetes mellitus, continuous glucose sensor, and the development of an artificial pancreas.  Other research interests include using continuous glucose monitoring and algorithms to control blood glucose levels in intensive care units."},{"lastName":"Gardner","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Clinical Pharmacology"}],"primaryAppointment":"Professor,Medicine - Clinical Pharmacology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4500&type=small&showNoImage","displayName":"Phyllis Gardner","firstName":"Phyllis","href":"http://med.stanford.edu/profiles/Phyllis_Gardner","researchInterest":"Ion channels and signal transduction;  patch clamp and fluorometric analysis; cell and molecular biology; cystic fibrosis gene therapy."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Knox","clinicalFocus":[{"focus":"Radiation Oncology"},{"focus":"Radiation Therapy"},{"focus":"Lymphoma, Transplantation, Breast Cancer, Targeted Therapies"}],"appointments":[{"appointment":"Associate Professor,Radiation Oncology - Radiation Therapy"},{"appointment":"Member,Bio-X"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Radiation Oncology - Radiation Therapy","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4699&type=small&showNoImage","displayName":"Susan Knox","firstName":"Susan","href":"http://med.stanford.edu/profiles/Susan_Knox","researchInterest":"Our interests include 1) study of the effect of radiation on regulatory cell subpopulations and co-stimulatory molecules, 2) use of radiation as an immune modulator for optimization of transplant regimens, 3) the role of radiation in tumor vaccine strategies, 4) study of new radiosensitizers and radioprotectors, and 5) discovery of new targeted therapies for the treatment of solid tumors."},{"lastName":"Kao","clinicalFocus":[{"focus":"Pulmonary Disease"},{"focus":"Pulmonology (Lung) and Critical Care "}],"appointments":[{"appointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine"}],"primaryAppointment":"Associate Professor,Medicine - Pulmonary & Critical Care Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=5961&type=small&showNoImage","displayName":"Peter Kao","firstName":"Peter","href":"http://med.stanford.edu/profiles/Peter_Kao","researchInterest":"Our research program has several active projects:\r\n1.) Pulmonary Vascular Disease \u0096 Simvastatin reversed experimental pulmonary hypertension, and is safe for treatment of patients. Blinded clinical trials of efficacy are in progress.\r\n2.) Lung inflammation and regeneration (stem cells)\r\n3.) Lung surfactant rheology and oxidative stress\r\n4.) Gene regulation by RNA binding proteins, NF45 and NF90 through transcriptional and posttranscriptional mechanisms"},{"lastName":"Bollyky","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Medicine - Infectious Diseases"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Assistant Professor,Medicine - Infectious Diseases","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35956&type=small&showNoImage","displayName":"Paul Bollyky","firstName":"Paul","href":"http://med.stanford.edu/profiles/Paul_Bollyky","researchInterest":"Our research is focused on the role of extracellular matrix (ECM) in inflammation and infection.    In particular, we study how the ECM in injured and healing tissues provides contextual cues that drive the behavior of regulatory T-cells and other leukocytes. Our goals are 1. to understand how the matrix contributes both to normal wound healing and to immune dysregulation, such as that seen in asthma and autoimmunity, and 2. to devise novel strategies and tools to promote immune tolerance."},{"lastName":"Winslow","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Genetics"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Assistant Professor,Genetics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=24603&type=small&showNoImage","displayName":"Monte Winslow","firstName":"Monte","href":"http://med.stanford.edu/profiles/Monte_Winslow","researchInterest":"Our laboratory uses genome-wide methods to uncover alterations that drive cancer progression and metastasis in genetically-engineered mouse models of human cancers. We combine cell-culture based mechanistic studies with our ability to alter pathways of interest during tumor progression in vivo to better understand each step of metastatic spread and to uncover the therapeutic vulnerabilities of advanced cancer cells."},{"lastName":"Peltz","clinicalFocus":[],"appointments":[{"appointment":"Professor,Anesthesia"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Anesthesia","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8527&type=small&showNoImage","displayName":"Gary Peltz","firstName":"Gary","href":"http://med.stanford.edu/profiles/Gary_Peltz","researchInterest":"The laboratory develops and uses state of the art genomic methods to identify genetic factors affecting disease susceptibility, and to translate these findings into new treatments. We have developed a more efficient method for performing mouse genetic analysis, which has been used to analyze the genetic basis for 16 different biomedical traits. We are developing novel methods, and have developed a novel experimental platform that replaces mouse liver with functioning human liver tissue."},{"lastName":"Maecker","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor (Research),Microbiology & Immunology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor (Research),Microbiology & Immunology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=25058&type=small&showNoImage","displayName":"Holden Maecker","firstName":"Holden","href":"http://med.stanford.edu/profiles/Holden_Maecker","researchInterest":"I'm interested in immune monitoring of T cell responses to chronic pathogens such as CMV, and the correlation of T cell response signatures with disease protection."},{"lastName":"Strober","clinicalFocus":[{"focus":"Immunology and Rheumatology"},{"focus":"Rheumatology"}],"appointments":[{"appointment":"Professor,Medicine - Immunology & Rheumatology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Professor,Medicine - Immunology & Rheumatology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4152&type=small&showNoImage","displayName":"Samuel Strober","firstName":"Samuel","href":"http://med.stanford.edu/profiles/Samuel_Strober","researchInterest":"Mechanisms of immune tolerance; regulatory processes in autoimmunity and transplantation and extrathymic T cell maturation."},{"lastName":"Ilovich","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Radiology"}],"primaryAppointment":"Postdoctoral Research fellow, Radiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=30109&type=small&showNoImage","displayName":"Ohad Ilovich","firstName":"Ohad","href":"http://med.stanford.edu/profiles/Ohad_Ilovich","researchInterest":""},{"lastName":"Dhabhar","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Psychiatry & Behavioral Science - Psychosocial"}],"primaryAppointment":"Associate Professor,Psychiatry & Behavioral Science - Psychosocial","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=7313&type=small&showNoImage","displayName":"Firdaus Dhabhar","firstName":"Firdaus","href":"http://med.stanford.edu/profiles/Firdaus_Dhabhar","researchInterest":"Although stress has a bad reputation the fight-or-flight stress response is nature's fundamental survival system. Our laboratory elucidates mechanisms that mediate the newly appreciated immunoenhancing effects of short-term stress versus the well known immunosuppressive effects of long-term stress. We investigate stress effects on leukocyte trafficking, cytokine gene/protein expression, and innate/adaptive immunity, in preclinical & clinical models of skin immunity, vaccines, surgery, & cancer."}]}