{"result":[{"lastName":"Crasta","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, School of Medicine"}],"primaryAppointment":"Postdoctoral Research fellow, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10372&type=small&showNoImage","displayName":"Sheela Crasta","firstName":"Sheela","href":"http://med.stanford.edu/profiles/Sheela_Crasta","researchInterest":""},{"lastName":"Bhalla","clinicalFocus":[{"focus":"Nephrology"},{"focus":"Nephrology (Kidney)"},{"focus":"Diabtetic Kidney Disease"},{"focus":"Hypertension"}],"appointments":[{"appointment":"Assistant Professor,Medicine - Nephrology"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Assistant Professor,Medicine - Nephrology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8442&type=small&showNoImage","displayName":"Vivek Bhalla, MD","firstName":"Vivek","href":"http://med.stanford.edu/profiles/Vivek_Bhalla","researchInterest":"Dr. Bhalla's research interests are in the pathogenesis of diabetic kidney disease and salt-sensitive hypertension. Using molecular and transgenic approaches, the laboratory is interested in elucidating regulators of oxidative and carbonyl stress in glomeruli. We interface these studies with collaborative projects on biomarkers for human diabetic nephropathy. \r\n\r\nThe laboratory also focuses on molecular mechanisms of insulin and aldosterone-induced sodium transport in the distal nephron."},{"lastName":"Jamison","clinicalFocus":[],"appointments":[{"appointment":"Professor Emeritus,Medicine - Nephrology"},{"appointment":"Emeritus Faculty, Acad Council,Medicine - Nephrology"},{"appointment":"Academic Secretary,Academic Secretary's Office"}],"primaryAppointment":"Professor Emeritus,Medicine - Nephrology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4541&type=small&showNoImage","displayName":"Rex L. Jamison","firstName":"Rex","href":"http://med.stanford.edu/profiles/Rex_Jamison","researchInterest":"Patients with advanced chronic kidney disease and end stage kidney disease have high rates of cardiovascular mortality and morbidity.  The purpose of the Homocysteine Study was to determine if lowering their high plasma homocysteine levels would reduce their mortality.  Secondary endpoints included reductions in myocardial infarction, stroke, and amputation of a lower extremity.  The results showed there was no improvement in survival or reduction in the cardiovascular events."},{"lastName":"Goodman","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3813&type=small&showNoImage","displayName":"Miriam B. Goodman","firstName":"Miriam","href":"http://med.stanford.edu/profiles/Miriam_Goodman","researchInterest":"We study the molecular events that give rise to the sensation of touch and temperature in C. elegans. To do this, we use a combination of quantitative behavioral analysis, genetics, in vivo electrophysiology, and heterologous expression of ion channels.  We also collaborate with Pruitt's group in Mechanical Engineering to develop and fabricate novel devices for the study of sensory transduction."},{"lastName":"O'Brodovich","clinicalFocus":[{"focus":"Pediatric Pulmonary"},{"focus":"Pulmonary Medicine/Cystic Fibrosis, Pediatric"}],"appointments":[{"appointment":"Professor,Pediatrics"},{"appointment":"Member,Child Health Research Institute"}],"primaryAppointment":"Professor,Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=8414&type=small&showNoImage","displayName":"Hugh O'Brodovich","firstName":"Hugh","href":"http://med.stanford.edu/profiles/Hugh_O'Brodovich","researchInterest":"Clinical: \r\nPulmonary edema, acute respiratory distress syndromes (ARDS), hyaline membrane disease (HMD), bronchopulmonary dysplasia (BPD)\r\n\r\nBasic Science: \r\nLung epithelial sodium transport\r\nGenetic influences on the development of BPD"},{"lastName":"Kopito","clinicalFocus":[],"appointments":[{"appointment":"Professor,Biology (School of Humanities and Sciences)"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Biology (School of Humanities and Sciences)","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6227&type=small&showNoImage","displayName":"Ron Kopito","firstName":"Ron","href":"http://med.stanford.edu/profiles/Ron_Kopito","researchInterest":"Our research is concerned with elucidating the basic cellular molecular mechanisms that underly the recognition and destruction of misfolded or mis-assembled proteins in eukaryotic cells.  We study dominatly inherited human neurodegenerative disorders like Alzheimer's, Huntington's or Parkinson's diseases that are caused by the failure of this system to effectively recognize and destroy such proteins."},{"lastName":"Rabkin","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Nephrology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Nephrology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=6052&type=small&showNoImage","displayName":"Ralph Rabkin","firstName":"Ralph","href":"http://med.stanford.edu/profiles/Ralph_Rabkin","researchInterest":"Dr Rabkin is examining the mechanism of the acquired resistance to hormones that develops in kidney failure.In particular he is studying the impact of kidney failure on the action of growth hormone and the role of impaired signal transduction as a cause of growth hormone resistance. He is also engaged in the study of growth factors in diabetic kidney disease."},{"lastName":"Koch","clinicalFocus":[],"appointments":[{"appointment":"Senior Director, Discovery & Technological Service Centers,Dean's Office - Senior Associate Dean for Research"},{"appointment":"Admin Services Manager,Dean's Office - Senior Associate Dean for Research"}],"primaryAppointment":"Senior Director, Discovery & Technological Service Centers,Dean's Office - Senior Associate Dean for Research","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=25427&type=small&showNoImage","displayName":"Bruce Koch, Ph.D.","firstName":"Bruce","href":"http://med.stanford.edu/profiles/Bruce_Koch","researchInterest":""},{"lastName":"Gardner","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Clinical Pharmacology"}],"primaryAppointment":"Professor,Medicine - Clinical Pharmacology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4500&type=small&showNoImage","displayName":"Phyllis Gardner","firstName":"Phyllis","href":"http://med.stanford.edu/profiles/Phyllis_Gardner","researchInterest":"Ion channels and signal transduction;  patch clamp and fluorometric analysis; cell and molecular biology; cystic fibrosis gene therapy."},{"lastName":"Maduke","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Molecular & Cellular Physiology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Associate Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3812&type=small&showNoImage","displayName":"Merritt Maduke","firstName":"Merritt","href":"http://med.stanford.edu/profiles/Merritt_Maduke","researchInterest":"Molecular mechanisms of chloride channels & transporters studied by integration of structural and electrophysiological methods."},{"lastName":"Ring","clinicalFocus":[],"appointments":[{"appointment":"MD Student, School of Medicine"},{"appointment":"Ph.D., Structural Biology"}],"primaryAppointment":"MD Student, School of Medicine","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=17919&type=small&showNoImage","displayName":"Aaron Ring","firstName":"Aaron","href":"http://med.stanford.edu/profiles/Aaron_Ring","researchInterest":""},{"lastName":"Hu","clinicalFocus":[],"appointments":[{"appointment":"Associate Professor,Obstetrics & Gynecology"},{"appointment":"Member,Stanford Cancer Institute"}],"primaryAppointment":"Associate Professor,Obstetrics & Gynecology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10405&type=small&showNoImage","displayName":"Mickey Hu","firstName":"Mickey","href":"http://med.stanford.edu/profiles/Mickey_Hu","researchInterest":""},{"lastName":"Vanni","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Pediatrics"}],"primaryAppointment":"Postdoctoral Research fellow, Pediatrics","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=37642&type=small&showNoImage","displayName":"Emilia Vanni","firstName":"Emilia","href":"http://med.stanford.edu/profiles/Emilia_Vanni","researchInterest":""},{"lastName":"Eastwood","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=10621&type=small&showNoImage","displayName":"Amy L Eastwood","firstName":"Amy","href":"http://med.stanford.edu/profiles/Amy_Eastwood","researchInterest":"Dr. Amy Eastwood\u0092s career has not just bloomed - it has rocketed.  From her takeoff in high school where her chemistry teacher inspired her to pursue a career in science, Dr. Eastwood obtained her Ph.D. at Caltech University, which in turn drew her interest to look at her research on ion channels in a more natural environment.  \r\n\r\nHouston, we have found C. elegans. Dr. Eastwood came to Stanford University in late 2008 and now, with the Stanford University\u0092s Dean Fellowship and a NIH NRSA Fello"},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4007&type=small&showNoImage","displayName":"Tobias Meyer","firstName":"Tobias","href":"http://med.stanford.edu/profiles/Tobias_Meyer","researchInterest":"CELLULAR INFORMATION PROCESSING  The main problem in signal transduction is to understand how different receptor-stimuli specifically control diverse cell functions. We are using automated microscopy, live-cell fluorescent biosensors and perturbations of predicted signaling proteins to systematically dissect signaling networks.  This allows us to identify signaling modules and to elucidate and ultimately model the flow of cellular information."},{"lastName":"Tan","clinicalFocus":[{"focus":"Kidney and Pancreas Transplantation"},{"focus":"Nephrology"},{"focus":"Nephrology (Kidney)"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Medicine - Nephrology"},{"appointment":"MS, Dean's Office"}],"primaryAppointment":"Associate Professor - Med Center Line,Medicine - Nephrology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3846&type=small&showNoImage","displayName":"Jane C. Tan","firstName":"Jane","href":"http://med.stanford.edu/profiles/Jane_Tan","researchInterest":"My research relates to issues pertaining to clinical kidney transplantation. We have ongoing studies on the following topics.\r\n1. Renal senescence and kidney transplant, and chronic allograft nephropathy.\r\n2. Living donor safety and response to uninephrectomy.\r\n3. Biomarkers for post-transplant monitoring."},{"lastName":"Meyer","clinicalFocus":[],"appointments":[{"appointment":"Professor,Medicine - Nephrology"}],"primaryAppointment":"Professor,Medicine - Nephrology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4497&type=small&showNoImage","displayName":"Timothy Meyer","firstName":"Timothy","href":"http://med.stanford.edu/profiles/Timothy_Meyer","researchInterest":"Inadequate removal of uremic solutes contributes to widespread illness in the more than 350,000 Americans maintained on hemodialysis.   But we know remarkably little about these solutes.  Dr. Meyer's research efforts are focused on identifying which uremic solutes are toxic, how these solutes are made, and how their production could be decreased or their removal  could be increased.  We should be able to improve treatment if we knew more about what we are trying to remove."},{"lastName":"O'Brien","clinicalFocus":[],"appointments":[{"appointment":"Assistant Professor,Molecular & Cellular Physiology"}],"primaryAppointment":"Assistant Professor,Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=35098&type=small&showNoImage","displayName":"Lucy Erin O'Brien","firstName":"Lucy","href":"http://med.stanford.edu/profiles/Lucy_O'Brien","researchInterest":"Many adult organs tune their functional capacity to variable levels of physiologic demand.  Adaptive organ resizing breaks the allometry of the body plan that was established during development, suggesting that it occurs through different mechanisms.  Emerging evidence points to stem cells as key players in these mechanisms.  We use the Drosophila midgut, a stem-cell based organ analogous to the vertebrate small intestine, as a simple model to uncover the rules that govern adaptive remodeling."},{"lastName":"Myers","clinicalFocus":[],"appointments":[{"appointment":"Emeritus Faculty, Acad Council,Medicine - Nephrology"}],"primaryAppointment":"Emeritus Faculty, Acad Council,Medicine - Nephrology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4332&type=small&showNoImage","displayName":"Bryan Myers","firstName":"Bryan","href":"http://med.stanford.edu/profiles/Bryan_Myers","researchInterest":"A novel approach is used to evaluate glomerular disease in humans, and its progression.  A combination of physiologic techniques, a morphometric analysis of glomeruli obtained by biopsy, and mathematical modeling of glomerular ultrafiltration is used to quantify the extent of glomerular injury in humans for the first time."},{"lastName":"Kambham","clinicalFocus":[{"focus":"Pathology and Laboratory Medicine"},{"focus":"Renal Pathology"},{"focus":"Anatomic Pathology"}],"appointments":[{"appointment":"Associate Professor - Med Center Line,Pathology"}],"primaryAppointment":"Associate Professor - Med Center Line,Pathology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=3829&type=small&showNoImage","displayName":"Neeraja Kambham","firstName":"Neeraja","href":"http://med.stanford.edu/profiles/Neeraja_Kambham","researchInterest":"Research interests primarily involve medical diseases of the native and transplant kidney. Other interests include liver transplantation pathology and gastrointestinal pathology."},{"lastName":"Anand","clinicalFocus":[],"appointments":[{"appointment":"MS, Dean's Office"},{"appointment":"Postdoctoral Research fellow, School of Medicine"}],"primaryAppointment":"MS, Dean's Office","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=13520&type=small&showNoImage","displayName":"Shuchi Anand","firstName":"Shuchi","href":"http://med.stanford.edu/profiles/Shuchi_Anand","researchInterest":"ESRD and physical activity\r\nESRD and vitamin D deficiency\r\nManagement of CKD and ESRD in developing regions"},{"lastName":"Mochly-Rosen","clinicalFocus":[],"appointments":[{"appointment":"Professor,Chemical and Systems Biology"},{"appointment":"Member,Bio-X"}],"primaryAppointment":"Professor,Chemical and Systems Biology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=4256&type=small&showNoImage","displayName":"Daria Mochly-Rosen","firstName":"Daria","href":"http://med.stanford.edu/profiles/Daria_Mochly-Rosen","researchInterest":"Two areas:  1. Using rationally-designed peptide inhibitors to study protein-protein interactions in cell signaling.  We focus on protein kinase C (PKC)-mediated signal transduction and on mitochondrial dynamics in several disease models. 2. Using small molecules (identified in a high throughput screens and synthetic chemistry) as activators and inhibitors of aldehyde dehydrogenases, a family of detoxifying enzymes, we study their involvement  in normal cells and in models of human diseases."},{"lastName":"Mendoza","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology"}],"primaryAppointment":"Postdoctoral Research fellow, Molecular & Cellular Physiology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=29257&type=small&showNoImage","displayName":"Juan L. Mendoza","firstName":"Juan","href":"http://med.stanford.edu/profiles/Juan_Mendoza","researchInterest":""},{"lastName":"Houschyar","clinicalFocus":[],"appointments":[{"appointment":"Postdoctoral Research fellow, Surgery"}],"primaryAppointment":"Postdoctoral Research fellow, Surgery","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=34645&type=small&showNoImage","displayName":"Khosrow Houschyar","firstName":"Khosrow","href":"http://med.stanford.edu/profiles/Khosrow_Houschyar","researchInterest":""},{"lastName":"Chang","clinicalFocus":[{"focus":"Nephrology"},{"focus":"chronic kidney disease"},{"focus":"hypertension"}],"appointments":[{"appointment":"Instructor,Medicine - Nephrology"}],"primaryAppointment":"Instructor,Medicine - Nephrology","imageUrl":"http://med.stanford.edu/profiles/viewImage?facultyId=9428&type=small&showNoImage","displayName":"Tara I. Chang","firstName":"Tara","href":"http://med.stanford.edu/profiles/Tara_Chang","researchInterest":"Cardiovascular disease, and specifically hypertension, in patients with chronic kidney disease and end-stage renal disease on dialysis."}]}