Vivek Bhalla, MD
Publication Details
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SGK1: a rapid aldosterone-induced regulator of renal sodium reabsorption.
Physiology (Bethesda). 2005: 134-9
Recently, substantial progress has been made in understanding the mechanisms by which aldosterone rapidly stimulates sodium transport in the distal nephron and other tight epithelia. Serum- and glucocorticoid-regulated kinase 1 (SGK1) has been identified as an important mediator of this process. Its physiological relevance has been revealed through heterologous expression in cultured cells and generation of SGK1 knockout mice.
