Terrence Blaschke
Publication Details
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Variable adherence to prescribed dosing regimens for protease inhibitors: scope and outcomes.
Curr Opin HIV AIDS. 2008; (6): 603-7
It is generally accepted that a high degree of adherence to the dosing regimens of protease inhibitors is essential to avoid virological failure. It is also believed that once-daily dosing of protease inhibitors, by improving adherence, will lead to better outcomes. This review will discuss the patterns of adherence for once-daily and twice-daily regimens and illustrate how differences in these patterns might favor twice-daily regimens in some settings.
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