Department of Medicine

William Clusin, MD

Publication Details

  • Spatial heterogeneity of calcium transient alternans during the early phase of myocardial ischemia in the blood-perfused rabbit heart.

    Qian YW, Clusin WT, Lin SF, Han J, Sung RJ. Circulation. 2001; 104 (17): 2082-7

    Optical mapping of cytosolic calcium transients in intact mammalian hearts is now possible using long-wavelength [Ca(2+)](i) indicators. We propose that beat-to-beat [Ca(2+)](i) transient alternans during ischemia may lead to spatial and temporal heterogeneity of calcium-activated membrane currents.

    PubMedID: 11673350

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