Publications
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Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.
Leeper NJ,
Raiesdana A, Kojima Y, Kundu RK, Cheng H, Maegdefessel L, Toh R, Ahn GO, Ali ZA, Anderson DR, Miller CL, Roberts SC, Spin JM, de Almeida PE, Wu JC, Xu B, Cheng K, Quertermous M, Kundu S, Kortekaas KE, Berzin E, Downing KP, Dalman RL, Tsao PS, Schadt EE, Owens GK, Quertermous T.
Arterioscler Thromb Vasc Biol.
2013;
33
(1):
e1-e10
-
Genetics of peripheral artery disease.
Leeper NJ,
Kullo IJ, Cooke JP.
Circulation.
2012;
125
(25):
3220-8
-
Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development.
Maegdefessel L,
Azuma J, Toh R, Merk DR, Deng A, Chin JT, Raaz U, Schoelmerich AM, Raiesdana A, Leeper NJ, McConnell MV, Dalman RL, Spin JM, Tsao PS.
J Clin Invest.
2012;
122
(2):
497-506
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MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion.
Maegdefessel L,
Azuma J, Toh R, Deng A, Merk DR, Raiesdana A, Leeper NJ, Raaz U, Schoelmerich AM, McConnell MV, Dalman RL, Spin JM, Tsao PS.
Sci Transl Med.
2012;
4
(122):
122ra22
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MicroRNA and mechanisms of impaired angiogenesis in diabetes mellitus.
Leeper NJ,
Cooke JP.
Circulation.
2011;
123
(3):
236-8
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MicroRNA-26a is a novel regulator of vascular smooth muscle cell function.
Leeper NJ,
Raiesdana A, Kojima Y, Chun HJ, Azuma J, Maegdefessel L, Kundu RK, Quertermous T, Tsao PS, Spin JM.
J Cell Physiol.
2011;
226
(4):
1035-43
-
Stem cell therapy for vascular regeneration: adult, embryonic, and induced pluripotent stem cells.
Leeper NJ,
Hunter AL, Cooke JP.
Circulation.
2010;
122
(5):
517-26
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Upregulation of the apelin-APJ pathway promotes neointima formation in the carotid ligation model in mouse.
Kojima Y,
Kundu RK, Cox CM, Leeper NJ, Anderson JA, Chun HJ, Ali ZA, Ashley EA, Krieg PA, Quertermous T.
Cardiovasc Res.
2010;
87
(1):
156-65
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Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation.
Leeper NJ,
Tedesco MM, Kojima Y, Schultz GM, Kundu RK, Ashley EA, Tsao PS, Dalman RL, Quertermous T.
Am J Physiol Heart Circ Physiol.
2009;
296
(5):
H1329-35
-
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis.
Chun HJ,
Ali ZA, Kojima Y, Kundu RK, Sheikh AY, Agrawal R, Zheng L, Leeper NJ, Pearl NE, Patterson AJ, Anderson JP, Tsao PS, Lenardo MJ, Ashley EA, Quertermous T.
J Clin Invest.
2008;
118
(10):
3343-54
-
Clinical problem-solving. Fool's Gold.
Leeper NJ,
Dhaliwal G, Saint S, Witteles RM.
N Engl J Med.
2008;
359
(19):
2035-41
-
Prognostic value of heart rate increase at onset of exercise testing.
Leeper NJ,
Dewey FE, Ashley EA, Sandri M, Tan SY, Hadley D, Myers J, Froelicher V.
Circulation.
2007;
115
(4):
468-74
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Statin use in patients with extremely low low-density lipoprotein levels is associated with improved survival.
Leeper NJ,
Ardehali R, deGoma EM, Heidenreich PA.
Circulation.
2007;
116
(6):
613-8
-
Clinical problem-solving. One surprise after another.
Leeper NJ,
Wener LS, Dhaliwal G, Saint S, Wachter RM.
N Engl J Med.
2005;
352
(14):
1474-9
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Cloning of a unique lipase from endothelial cells extends the lipase gene family.
Hirata K,
Dichek HL, Cioffi JA, Choi SY, Leeper NJ, Quintana L, Kronmal GS, Cooper AD, Quertermous T.
J Biol Chem.
1999;
274
(20):
14170-5
-
Tetracycline-regulatable expression vectors tightly regulate in vitro gene expression of secreted proteins.
Sturtz FG,
Cioffi L, Wittmer S, Sonk MJ, Shafer A, Li Y, Leeper NJ, Smith-Gbur J, Shulok J, Platika D.
Gene.
1998;
221
(2):
279-85
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Exercise capacity is the strongest predictor of mortality in patients with peripheral arterial disease.
Leeper NJ,
Myers J, Zhou M, Nead KT, Syed A, Kojima Y, Caceres RD, Cooke JP.
J Vasc Surg.
2013;
57
(3):
728-33
-
Usefulness of the addition of beta-2-microglobulin, cystatin C and C-reactive protein to an established risk factors model to improve mortality risk prediction in patients undergoing coronary angiography.
Nead KT,
Zhou MJ, Caceres RD, Sharp SJ, Wehner MR, Olin JW, Cooke JP, Leeper NJ.
Am J Cardiol.
2013;
111
(6):
851-6
-
Walking impairment questionnaire improves mortality risk prediction models in a high-risk cohort independent of peripheral arterial disease status.
Nead KT,
Zhou M, Caceres RD, Olin JW, Cooke JP, Leeper NJ.
Circ Cardiovasc Qual Outcomes.
2013;
6
(3):
255-61
-
Two decades of progress in vascular medicine.
Leeper NJ,
Lee JT, Cooke JP.
Am J Med.
2011;
124
(9):
791-2
-
Endogenous regulation of cardiovascular function by apelin-APJ.
Charo DN,
Ho M, Fajardo G, Kawana M, Kundu RK, Sheikh AY, Finsterbach TP, Leeper NJ, Ernst KV, Chen MM, Ho YD, Chun HJ, Bernstein D, Ashley EA, Quertermous T.
Am J Physiol Heart Circ Physiol.
2009;
297
(5):
H1904-13
-
Clinical significance of high-density lipoprotein cholesterol in patients with low low-density lipoprotein cholesterol.
deGoma EM,
Leeper NJ, Heidenreich PA.
J Am Coll Cardiol.
2008;
51
(1):
49-55
-
Clinical dilemmas in treating left ventricular thrombus.
Leeper NJ,
Gupta A, Schnittger I, Wu JC.
Int J Cardiol.
2007;
114
(3):
e118-9
-
Right coronary cameral fistula resulting from surgery of double chamber right ventricle.
Leeper NJ,
Gupta A, Murphy DJ, Wu JC.
J Am Soc Echocardiogr.
2006;
19
(9):
1191.e9-11
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The effect of preoperative statin therapy on cardiovascular outcomes in patients undergoing infrainguinal vascular surgery.
Ward RP,
Leeper NJ, Kirkpatrick JN, Lang RM, Sorrentino MJ, Williams KA.
Int J Cardiol.
2005;
104
(3):
264-8
-
Gender does not influence outcomes after iliac angioplasty.
Orr JD,
Leeper NJ, Funaki B, Leef J, Gewertz BL, Desai TR.
Ann Vasc Surg.
2002;
16
(1):
55-60
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Interleukin-6 causes endothelial barrier dysfunction via the protein kinase C pathway.
Desai TR,
Leeper NJ, Hynes KL, Gewertz BL.
J Surg Res.
2002;
104
(2):
118-23
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