Publications
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Neonatal β cell development in mice and humans is regulated by calcineurin/NFAT.
Goodyer WR,
Gu X, Liu Y, Bottino R, Crabtree GR, Kim SK.
Dev Cell.
2012;
23
(1):
21-34
-
PDGF signalling controls age-dependent proliferation in pancreatic β-cells.
Chen H,
Gu X, Liu Y, Wang J, Wirt SE, Bottino R, Schorle H, Sage J, Kim SK.
Nature.
2011;
478
(7369):
349-55
-
Specification of Drosophila corpora cardiaca neuroendocrine cells from mesoderm is regulated by Notch signaling.
Park S,
Bustamante EL, Antonova J, McLean GW, Kim SK.
PLoS Genet.
2011;
7
(8):
e1002241
-
Targeting SOX17 in human embryonic stem cells creates unique strategies for isolating and analyzing developing endoderm.
Wang P,
Rodriguez RT, Wang J, Ghodasara A, Kim SK.
Cell Stem Cell.
2011;
8
(3):
335-46
-
Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function.
Heit JJ,
Apelqvist AA, Gu X, Winslow MM, Neilson JR, Crabtree GR, Kim SK.
Nature.
2006;
443
(7109):
345-9
-
Conserved mechanisms of glucose sensing and regulation by Drosophila corpora cardiaca cells.
Kim SK,
Rulifson EJ.
Nature.
2004;
431
(7006):
316-20
-
Gene regulatory networks governing pancreas development.
Arda HE,
Benitez CM, Kim SK.
Dev Cell.
2013;
25
(1):
5-13
-
A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells.
Wang P,
McKnight KD, Wong DJ, Rodriguez RT, Sugiyama T, Gu X, Ghodasara A, Qu K, Chang HY, Kim SK.
Stem Cells Dev.
2012;
21
(12):
2273-87
-
Deconstructing pancreas developmental biology.
Benitez CM,
Goodyer WR, Kim SK.
Cold Spring Harb Perspect Biol.
2012;
4
(6)
-
Gut insulin from Foxo1 loss.
Kim SK,
Nat Genet.
2012;
44
(4):
363-4
-
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters.
Hung T,
Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, van de Vijver M, Sukumar S, Whitfield ML, Kellis M, Xiong Y, Wong DJ, Chang HY.
Nat Genet.
2011;
43
(7):
621-9
-
Deconstructing pancreas development to reconstruct human islets from pluripotent stem cells.
McKnight KD,
Wang P, Kim SK.
Cell Stem Cell.
2010;
6
(4):
300-8
-
Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus.
Chen H,
Gu X, Su IH, Bottino R, Contreras JL, Tarakhovsky A, Kim SK.
Genes Dev.
2009;
23
(8):
975-85
-
Characterization of six new human embryonic stem cell lines (HSF7, -8, -9, -10, -12, and -13) derived under minimal-animal component conditions.
Chavez SL,
Meneses JJ, Nguyen HN, Kim SK, Pera RA.
Stem Cells Dev.
2008;
17
(3):
535-46
-
Fluorescence-activated cell sorting purification of pancreatic progenitor cells.
Sugiyama T,
Kim SK.
Diabetes Obes Metab.
2008:
10 Suppl 4
179-85
-
Conserved markers of fetal pancreatic epithelium permit prospective isolation of islet progenitor cells by FACS.
Sugiyama T,
Rodriguez RT, McLean GW, Kim SK.
Proc Natl Acad Sci U S A.
2007;
104
(1):
175-80
-
Glucose infusion in mice: a new model to induce beta-cell replication.
Alonso LC,
Yokoe T, Zhang P, Scott DK, Kim SK, O'Donnell CP, Garcia-Ocaña A.
Diabetes.
2007;
56
(7):
1792-801
-
Menin controls growth of pancreatic beta-cells in pregnant mice and promotes gestational diabetes mellitus.
Karnik SK,
Chen H, McLean GW, Heit JJ, Gu X, Zhang AY, Fontaine M, Yen MH, Kim SK.
Science.
2007;
318
(5851):
806-9
-
Menin-mediated caspase 8 expression in suppressing multiple endocrine neoplasia type 1.
La P,
Yang Y, Karnik SK, Silva AC, Schnepp RW, Kim SK, Hua X.
J Biol Chem.
2007;
282
(43):
31332-40
-
Wnt signaling regulates pancreatic beta cell proliferation.
Rulifson IC,
Karnik SK, Heiser PW, ten Berge D, Chen H, Gu X, Taketo MM, Nusse R, Hebrok M, Kim SK.
Proc Natl Acad Sci U S A.
2007;
104
(15):
6247-52
-
Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus.
Smart NG,
Apelqvist AA, Gu X, Harmon EB, Topper JN, MacDonald RJ, Kim SK.
PLoS Biol.
2006;
4
(2):
e39
-
Intrinsic regulators of pancreatic beta-cell proliferation.
Heit JJ,
Karnik SK, Kim SK.
Annu Rev Cell Dev Biol.
2006:
22
311-38
-
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21.
Arron JR,
Winslow MM, Polleri A, Chang CP, Wu H, Gao X, Neilson JR, Chen L, Heit JJ, Kim SK, Yamasaki N, Miyakawa T, Francke U, Graef IA, Crabtree GR.
Nature.
2006;
441
(7093):
595-600
-
The ATP-sensitive potassium (KATP) channel-encoded dSUR gene is required for Drosophila heart function and is regulated by tinman.
Akasaka T,
Klinedinst S, Ocorr K, Bustamante EL, Kim SK, Bodmer R.
Proc Natl Acad Sci U S A.
2006;
103
(32):
11999-2004
-
Differentiation of insulin-producing cells from human neural progenitor cells.
Hori Y,
Gu X, Xie X, Kim SK.
PLoS Med.
2005;
2
(4):
e103
-
Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c.
Karnik SK,
Hughes CM, Gu X, Rozenblatt-Rosen O, McLean GW, Xiong Y, Meyerson M, Kim SK.
Proc Natl Acad Sci U S A.
2005;
102
(41):
14659-64
-
Embryonic stem cells and islet replacement in diabetes mellitus.
Heit JJ,
Kim SK.
Pediatr Diabetes.
2004:
5 Suppl 2
5-15
-
GDF11 modulates NGN3+ islet progenitor cell number and promotes beta-cell differentiation in pancreas development.
Harmon EB,
Apelqvist AA, Smart NG, Gu X, Osborne DH, Kim SK.
Development.
2004;
131
(24):
6163-74
-
Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes.
Rulifson EJ,
Kim SK, Nusse R.
Science.
2002;
296
(5570):
1118-20
-
Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells.
Hori Y,
Rulifson IC, Tsai BC, Heit JJ, Cahoy JD, Kim SK.
Proc Natl Acad Sci U S A.
2002;
99
(25):
16105-10
-
Hedgehog signaling in gastrointestinal development and disease.
Harmon EB,
Ko AH, Kim SK.
Curr Mol Med.
2002;
2
(1):
67-82
-
Pancreatic islet cell replacement: successes and opportunities.
Kim SK,
Ann N Y Acad Sci.
2002:
961
41-3
-
Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus.
Kim SK,
Selleri L, Lee JS, Zhang AY, Gu X, Jacobs Y, Cleary ML.
Nat Genet.
2002;
30
(4):
430-5
-
Signaling and transcriptional control of pancreatic organogenesis.
Kim SK,
MacDonald RJ.
Curr Opin Genet Dev.
2002;
12
(5):
540-7
-
Intercellular signals regulating pancreas development and function.
Kim SK,
Hebrok M.
Genes Dev.
2001;
15
(2):
111-27
-
Activin receptor patterning of foregut organogenesis.
Kim SK,
Hebrok M, Li E, Oh SP, Schrewe H, Harmon EB, Lee JS, Melton DA.
Genes Dev.
2000;
14
(15):
1866-71
-
Regulation of pancreas development by hedgehog signaling.
Hebrok M,
Kim SK, St Jacques B, McMahon AP, Melton DA.
Development.
2000;
127
(22):
4905-13
-
Screening for novel pancreatic genes expressed during embryogenesis.
Hebrok M,
Kim SK, Melton DA.
Diabetes.
1999;
48
(8):
1550-6
-
Notochord repression of endodermal Sonic hedgehog permits pancreas development.
Hebrok M,
Kim SK, Melton DA.
Genes Dev.
1998;
12
(11):
1705-13
-
Pancreas development is promoted by cyclopamine, a hedgehog signaling inhibitor.
Kim SK,
Melton DA.
Proc Natl Acad Sci U S A.
1998;
95
(22):
13036-41
-
Notochord to endoderm signaling is required for pancreas development.
Kim SK,
Hebrok M, Melton DA.
Development.
1997;
124
(21):
4243-52
-
Pancreas development in the chick embryo.
Kim SK,
Hebrok M, Melton DA.
Cold Spring Harb Symp Quant Biol.
1997:
62
377-83
-
Chemotherapy and neutropenia.
Kim SK,
Demetri GD.
Hematol Oncol Clin North Am.
1996;
10
(2):
377-95
-
Control of cell density and pattern by intercellular signaling in Myxococcus development.
Kim SK,
Kaiser D, Kuspa A.
Annu Rev Microbiol.
1992:
46
117-39
-
Intercellular signaling in Myxococcus development: the role of C factor.
Kim SK,
Trends Genet.
1991 Nov-Dec;
7
(11-12):
361-5
-
C-factor has distinct aggregation and sporulation thresholds during Myxococcus development.
Kim SK,
Kaiser D.
J Bacteriol.
1991;
173
(5):
1722-8
-
C-factor: a cell-cell signaling protein required for fruiting body morphogenesis of M. xanthus.
Kim SK,
Kaiser D.
Cell.
1990;
61
(1):
19-26
-
Cell alignment required in differentiation of Myxococcus xanthus.
Kim SK,
Kaiser D.
Science.
1990;
249
(4971):
926-8
-
Cell motility is required for the transmission of C-factor, an intercellular signal that coordinates fruiting body morphogenesis of Myxococcus xanthus.
Kim SK,
Kaiser D.
Genes Dev.
1990;
4
(6):
896-904
-
Purification and properties of Myxococcus xanthus C-factor, an intercellular signaling protein.
Kim SK,
Kaiser D.
Proc Natl Acad Sci U S A.
1990;
87
(10):
3635-9
-
Rho-dependent transcription termination of a bacterial operon is antagonized by an extrachromosomal gene product.
Lagos R,
Jiang RZ, Kim S, Goldstein R.
Proc Natl Acad Sci U S A.
1986;
83
(24):
9561-5
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