Glenn Rosen

Publications

• An analysis of connective tissue disease-associated interstitial lung disease at a US Tertiary Care Center: better survival in patients with systemic sclerosis. Su R, Bennett M, Jacobs S, Hunter T, Bailey C, Krishnan E, Rosen G, Chung L. J Rheumatol. 2011; 38 (4): 693-701
• SPARC suppresses apoptosis of idiopathic pulmonary fibrosis fibroblasts through constitutive activation of beta-catenin. Chang W, Wei K, Jacobs SS, Upadhyay D, Weill D, Rosen GD. J Biol Chem. 2010; 285 (11): 8196-206
• Nicotine induces resistance to chemotherapy by modulating mitochondrial signaling in lung cancer. Zhang J, Kamdar O, Le W, Rosen GD, Upadhyay D. Am J Respir Cell Mol Biol. 2009; 40 (2): 135-46
• Air pollution induces enhanced mitochondrial oxidative stress in cystic fibrosis airway epithelium. Kamdar O, Le W, Zhang J, Ghio AJ, Rosen GD, Upadhyay D. FEBS Lett. 2008; 582 (25-26): 3601-6
• Ambient particulate matter induces alveolar epithelial cell cycle arrest: role of G1 cyclins. Zhang J, Ghio AJ, Gao M, Wei K, Rosen GD, Upadhyay D. FEBS Lett. 2007; 581 (27): 5315-20
• Bim mediates mitochondria-regulated particulate matter-induced apoptosis in alveolar epithelial cells. Zhang J, Ghio AJ, Chang W, Kamdar O, Rosen GD, Upadhyay D. FEBS Lett. 2007; 581 (22): 4148-52
• Fibroblast growth factor-10 prevents H2O2-induced cell cycle arrest by regulation of G1 cyclins and cyclin dependent kinases. Upadhyay D, Chang W, Wei K, Gao M, Rosen GD. FEBS Lett. 2007; 581 (2): 248-52
• A 35-year-old man with fever, dyspnea, and diffuse reticular opacities. Katikireddy CK, Krishna G, Keifer T, Kuschner W, Rosen G. Chest. 2006; 129 (2): 482-7
• Recurrence of pulmonary intravascular bronchoalveolar tumor with mediastinal metastasis 20 years later. Chen TM, Donington J, Mak G, Berry GJ, Ruoss SJ, Rosen GD, Upadhyay D. Respir Med. 2006; 100 (2): 367-70
• PG490-88, a derivative of triptolide, causes tumor regression and sensitizes tumors to chemotherapy. Fidler JM, Li K, Chung C, Wei K, Ross JA, Gao M, Rosen GD. Mol Cancer Ther. 2003; 2 (9): 855-62
• Oligoclonal CD4(+) T cell expansions in lung transplant recipients with obliterative bronchiolitis. Duncan SR, Leonard C, Theodore J, Lega M, Girgis RE, Rosen GD, Theofilopoulos AN. Am J Respir Crit Care Med. 2002; 165 (10): 1439-44
• PG490-88, a derivative of triptolide, attenuates obliterative airway disease in a mouse heterotopic tracheal allograft model. Leonard CT, Soccal PM, Berry GJ, Doyle RL, Theodore J, Duncan SR, Rosen GD. J Heart Lung Transplant. 2002; 21 (12): 1314-8
• Pharmacogenomics and the challenge to privacy. Vaszar LT, Rosen GD, Raffin TA. Pharmacogenomics J. 2002; 2 (3): 144-7
• The molecular biology of lung cancer. Ross JA, Rosen GD. Curr Opin Pulm Med. 2002; 8 (4): 265-9
• Triptolide sensitizes lung cancer cells to TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by inhibition of NF-kappaB activation. Lee KY, Park JS, Jee YK, Rosen GD. Exp Mol Med. 2002; 34 (6): 462-8
• Diversity of gene expression in adenocarcinoma of the lung. Garber ME, Troyanskaya OG, Schluens K, Petersen S, Thaesler Z, Pacyna-Gengelbach M, van de Rijn M, Rosen GD, Perou CM, Whyte RI, Altman RB, Brown PO, Botstein D, Petersen I. Proc Natl Acad Sci U S A. 2001; 98 (24): 13784-9
• PG490-88, a derivative of triptolide, blocks bleomycin-induced lung fibrosis. Krishna G, Liu K, Shigemitsu H, Gao M, Raffin TA, Rosen GD. Am J Pathol. 2001; 158 (3): 997-1004
• Triptolide and chemotherapy cooperate in tumor cell apoptosis. A role for the p53 pathway. Chang WT, Kang JJ, Lee KY, Wei K, Anderson E, Gotmare S, Ross JA, Rosen GD. J Biol Chem. 2001; 276 (3): 2221-7
• Tumor necrosis factor-related apoptosis-inducing ligand and chemotherapy cooperate to induce apoptosis in mesothelioma cell lines. Liu W, Bodle E, Chen JY, Gao M, Rosen GD, Broaddus VC. Am J Respir Cell Mol Biol. 2001; 25 (1): 111-8
• Dendritic cells and macrophages in lung allografts: A role in chronic rejection? Leonard CT, Soccal PM, Singer L, Berry GJ, Theodore J, Holt PG, Doyle RL, Rosen GD. Am J Respir Crit Care Med. 2000; 161 (4 Pt 1): 1349-54
• Thoracic lymphangiomas, lymphangiectasis, lymphangiomatosis, and lymphatic dysplasia syndrome. Faul JL, Berry GJ, Colby TV, Ruoss SJ, Walter MB, Rosen GD, Raffin TA. Am J Respir Crit Care Med. 2000; 161 (3 Pt 1): 1037-46
• Loss of STAT1 expression confers resistance to IFN-gamma-induced apoptosis in ME180 cells. Lee KY, Anderson E, Madani K, Rosen GD. FEBS Lett. 1999; 459 (3): 323-6
• PG490 (triptolide) cooperates with tumor necrosis factor-alpha to induce apoptosis in tumor cells. Lee KY, Chang W, Qiu D, Kao PN, Rosen GD. J Biol Chem. 1999; 274 (19): 13451-5
• Proteolytic cleavage of ras GTPase-activating protein during apoptosis. Wen LP, Madani K, Martin GA, Rosen GD. Cell Death Differ. 1998; 5 (9): 729-34
• Cleavage of focal adhesion kinase by caspases during apoptosis. Wen LP, Fahrni JA, Troie S, Guan JL, Orth K, Rosen GD. J Biol Chem. 1997; 272 (41): 26056-61
• Dexamethasone inhibits lung epithelial cell apoptosis induced by IFN-gamma and Fas. Wen LP, Madani K, Fahrni JA, Duncan SR, Rosen GD. Am J Physiol. 1997; 273 (5 Pt 1): L921-9
• Rapamycin inhibits development of obliterative airway disease in a murine heterotopic airway transplant model. Fahrni JA, Berry GJ, Morris RE, Rosen GD. Transplantation. 1997; 63 (4): 533-7
• Acid aspiration induced lung injury. New insights and therapeutic options. Matthay MA, Rosen GD. Am J Respir Crit Care Med. 1996; 154 (2 Pt 1): 277-8
• Airway epithelial cells produce stem cell factor. Wen LP, Fahrni JA, Matsui S, Rosen GD. Biochim Biophys Acta. 1996; 1314 (3): 183-6
• An intricate arrangement of binding sites for the Ets family of transcription factors regulates activity of the alpha 4 integrin gene promoter. Rosen GD, Barks JL, Iademarco MF, Fisher RJ, Dean DC. J Biol Chem. 1994; 269 (22): 15652-60
• Expanding roles for alpha 4 integrin and its ligands in development. Sheppard AM, Onken MD, Rosen GD, Noakes PG, Dean DC. Cell Adhes Commun. 1994; 2 (1): 27-43
• Multiple regulatory elements control the basal promoter activity of the human alpha 4 integrin gene. Audet JF, Masson JY, Rosen GD, Salesse C, Guérin SL. DNA Cell Biol. 1994; 13 (11): 1071-85
• The integrin alpha 4 beta 1 and its counter receptor VCAM-1 in development and immune function. Dean DC, Iademarco MF, Rosen GD, Sheppard AM. Am Rev Respir Dis. 1993; 148 (6 Pt 2): S43-6
• Characterization of the promoter for vascular cell adhesion molecule-1 (VCAM-1). Iademarco MF, McQuillan JJ, Rosen GD, Dean DC. J Biol Chem. 1992; 267 (23): 16323-9
• Roles for the integrin VLA-4 and its counter receptor VCAM-1 in myogenesis. Rosen GD, Sanes JR, LaChance R, Cunningham JM, Roman J, Dean DC. Cell. 1992; 69 (7): 1107-19
• Characterization of the alpha 4 integrin gene promoter. Rosen GD, Birkenmeier TM, Dean DC. Proc Natl Acad Sci U S A. 1991; 88 (10): 4094-8
• Glycoprotein synthesis and secretion. Expression of fibronectin and its cell surface receptors. Dean DC, Birkenmeier TM, Rosen GD, Weintraub SJ. Am Rev Respir Dis. 1991; 144 (3 Pt 2): S25-8
• Identification of a protein that interacts with the nuclear factor-1 (NF-1) binding site in cells that do not express NF-1: comparison to NF-1, cellular distribution, and effect on transcription. McQuillan JJ, Rosen GD, Birkenmeier TM, Dean DC. Nucleic Acids Res. 1991; 19 (23): 6627-31
• Identification of a cyclooxygenase-related gene and its potential role in prostaglandin formation. Rosen GD, Birkenmeier TM, Raz A, Holtzman MJ. Biochem Biophys Res Commun. 1989; 164 (3): 1358-65
• Uptake, release and novel species-dependent oxygenation of arachidonic acid in human and animal airway epithelial cells. Holtzman MJ, Hansbrough JR, Rosen GD, Turk J. Biochim Biophys Acta. 1988; 963 (3): 401-13