Sean M. Wu

Publications

• At a crossroad: cell therapy for cardiac repair. Deutsch MA, Sturzu A, Wu SM. Circ Res. 2013; 112 (6): 884-90
• Essential and unexpected role of YY1 to promote mesodermal cardiac differentiation Gregoire, S., Karra, R., Passer, D., Deutsch, M-A., Krane, M., Feistritzer, R., Sturzu, A., Domian, I.J., Saga, Y., Wu, S.M.. Circ Res. 2013: 112 900-910
• Of fish and mice: Clonal lineage analysis identifies divergence in myocardial development. Sharma, A., Wu, S.M.. Circ. Res.. 2013: 112 583-585
• Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5. Chen JX, Krane M, Deutsch MA, Wang L, Rav-Acha M, Gregoire S, Engels MC, Rajarajan K, Karra R, Abel ED, Wu JC, Milan D, Wu SM. Circ Res. 2012; 111 (1): 50-5
• Developmental and regenerative biology of multipotent cardiovascular progenitor cells. Sturzu AC, Wu SM. Circ Res. 2011; 108 (3): 353-64
• Harnessing the potential of induced pluripotent stem cells for regenerative medicine. Wu SM, Hochedlinger K. Nat Cell Biol. 2011; 13 (5): 497-505
• Generation of functional ventricular heart muscle from mouse ventricular progenitor cells. Domian IJ, Chiravuri M, van der Meer P, Feinberg AW, Shi X, Shao Y, Wu SM, Parker KK, Chien KR. Science. 2009; 326 (5951): 426-9
• Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Zhou B, Ma Q, Rajagopal S, Wu SM, Domian I, Rivera-Feliciano J, Jiang D, von Gise A, Ikeda S, Chien KR, Pu WT. Nature. 2008; 454 (7200): 109-13
• Mesp1 at the heart of mesoderm lineage specification. Wu SM, Cell Stem Cell. 2008; 3 (1): 1-2
• Origins and fates of cardiovascular progenitor cells. Wu SM, Chien KR, Mummery C. Cell. 2008; 132 (4): 537-43
• Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. Wu SM, Fujiwara Y, Cibulsky SM, Clapham DE, Lien CL, Schultheiss TM, Orkin SH. Cell. 2006; 127 (6): 1137-50
• Autophagy - the friendly fire in endothelial cell regeneration Sharma, A., Wu, S.M.. Am J Phys - Cell Physiology. 2013; 304 (7): C614-6
• Stem Cell Therapy in Chronic Ischemic Cardiomyopathy: A Meta-Analysis Kandala, J., Upadhyay, G.A., Pokushalov, E., Wu, S.M., Drachman, D.E., Singh, J.P.. Am J Cardiol. 2013 In Press
• iPS cell modeling of cardiometabolic diseases. Nakamura K, Hirano K, Wu SM. J Cardiovasc Transl Res. 2013; 6 (1): 46-53
• A Brief Primer on the Development of the Heart Gregoire S, Wu SM. Heart Failure, 2nd Ed.. 2012: Chapter 1
• Early cardiac development: a view from stem cells to embryos. Van Vliet P, Wu SM, Zaffran S, Pucéat M. Cardiovasc Res. 2012; 96 (3): 352-62
• Epigenetic mechanisms in cardiac development and disease. Vallaster M, Vallaster CD, Wu SM. Acta Biochim Biophys Sin (Shanghai). 2012; 44 (1): 92-102
• Putting the Pieces Together: Stem Cells and The Quest to Heal A Broken Heart Wu, S.M.,, Singh, J.. CardioSource World News. 2012: December 22-27
• Reprogramming of mouse, rat, pig, and human fibroblasts into iPS cells. Rajarajan K, Engels MC, Wu SM. Curr Protoc Mol Biol. 2012: Chapter 23 Unit 23.15.
• Reprogramming the beat: kicking it up a notch. Wu SM, Milan DJ. Circulation. 2012; 126 (9): 1009-11
• Small molecule regulators of Nkx2.5+ cardiomyoblasts proliferation and differentiation. Chen, W-P., Wu, S.M.. Journal of Cell Molecular Medicine. 2012; 16 (5): 961-965
• iPS cell-based modeling of complex human diseases. Hinson, J.T.,, Nakamura, K., Wu, S.M.. Drug Discovery Today: Disease Mechanisms. 2012 In Press.
• Regenerative strategies for cardiac disease Huang X, Oh JB, Wu SM. In: Stem Cells and Regenerative Medicine. Humana Press.. 2011: 1 579-593
• Cardiac progenitor cells: from embryonic to the aging heart. Liu, Y-H., Kuhn, E.B. and Wu, S.M.. Aging Health. 2010; 6 (6): 679-686
• Integrated aspects of cardiac cell therapy. Pijnappels, D.A.,, Gregoire, S., Wu, S.M.. Ann. N.Y. Acad. Sci.. 2010: 1188 7-14
• Isolation and functional characterization of pluripotent stem cell-derived cardiac progenitor cells. Huang X, Wu SM. Curr Protoc Stem Cell Biol. 2010: Chapter 1 Unit 1F.10
• Origin of multipotent cardiac progenitor cells in development and regeneration Kuhn, E.B., Wu, S.M.. J. Cell. Physiology. 2010; 225 (2): 321-325
• Promises and pitfalls in cell replacement therapy for heart failure. Krane M, Wernet O, Wu SM. Drug Discov Today Dis Mech. 2010; 7 (2): e109-e115
• Platypnea-orthodeoxia syndrome in two previously healthy adults: a case-based review Ptaszek LM, Saldana F, Palacios IF, Wu SM. Clinical Medicine Insights: Cardiology. 2009: 3 37-43
• VISIONS: the art of science. Wu SM, Mol Reprod Dev. 2009; 76 (6): 525
• Cardiovascular Stem Cells in Regenerative Medicine: Ready for Prime Time? Liu YH, Karra R, Wu SM. Drug Discov Today Ther Strateg. 2008; 5 (4): 201-207
• Differential regulation of the fibroblast growth factor (FGF) family by alpha(2)-macroglobulin: evidence for selective modulation of FGF-2-induced angiogenesis. Asplin IR, Wu SM, Mathew S, Bhattacharjee G, Pizzo SV. Blood. 2001; 97 (11): 3450-7
• alpha(2)-Macroglobulin from rheumatoid arthritis synovial fluid: functional analysis defines a role for oxidation in inflammation. Wu SM, Pizzo SV. Arch Biochem Biophys. 2001; 391 (1): 119-26
• The conformation-dependent interaction of alpha 2-macroglobulin with vascular endothelial growth factor. A novel mechanism of alpha 2-macroglobulin/growth factor binding. Bhattacharjee G, Asplin IR, Wu SM, Gawdi G, Pizzo SV. J Biol Chem. 2000; 275 (35): 26806-11
• a-Macroglobulins/Kunins Pizzo SV, Wu SM. In: Hemostasis and Thrombosis: Basic Principles and Clinical Practice, 4th Ed.. 2000: 367-379
• Mechanism of hypochlorite-mediated inactivation of proteinase inhibition by alpha 2-macroglobulin. Wu SM, Pizzo SV. Biochemistry. 1999; 38 (42): 13983-90
• Oxidized alpha2-macroglobulin (alpha2M) differentially regulates receptor binding by cytokines/growth factors: implications for tissue injury and repair mechanisms in inflammation. Wu SM, Patel DD, Pizzo SV. J Immunol. 1998; 161 (8): 4356-65
• Crashing the Boards: A User Friendly Study Guide for the USMLE Step 1 Yeh B, Paydafar JA, Flynn M, Biswas SS, Bulsara KR, Liao L, Wu SM. Lippincott-Raven. 1997 1
• The binding of receptor-recognized alpha2-macroglobulin to the low density lipoprotein receptor-related protein and the alpha2M signaling receptor is decoupled by oxidation. Wu SM, Boyer CM, Pizzo SV. J Biol Chem. 1997; 272 (33): 20627-35
• Low-density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor on murine peritoneal macrophages mediates the binding and catabolism of low-density lipoprotein. Wu SM, Pizzo SV. Arch Biochem Biophys. 1996; 326 (1): 39-47