Department: Medicine
Division: Blood and
Marrow Transplantation
- Faculty (12)
- Postdocs (9)
- All
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Academic Appointments
- Assistant Professor - Med Center Line, Medicine - Division: Blood and Marrow Transplantation
- Member, Cancer Center
Clinical Focus- Blood and Marrow Transplantation
- Hematology
Research InterestResearch interest in utilizing post-transplant adoptive cellular immunotherapy to reduce GVHD and relapse in patients with high risk hematologic malignancies.
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Academic Appointments
- Assistant Professor - Med Center Line, Medicine - Division: Blood and Marrow Transplantation
Clinical Focus- Blood and Marrow Transplantation
- Internal Medicine
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Academic Appointments
- Emeritus (Active) Professor, Medicine - Division: Blood and Marrow Transplantation
- Member, Cancer Center
Research InterestAllogeneic and autologous bone marrow transplantation (experimental and clinical) as a treatment modality for leukemia, lymphoma, Hodgkin's disease, multiple myeloma, hereditary disorders, immune defects and selective solid tumors. Development of novel preparatory regimens to prevent the recurrence of the underlying malignancies. Studies for the prevention of acute and chronic graft-versus-host disease. Testing of new anti-viral agents to prevent or treat viral infections.
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Academic Appointments
- Associate Professor - Med Center Line, Medicine - Division: Blood and Marrow Transplantation
- Member, Cancer Center
Clinical Focus- Blood and Marrow Transplantation
- Blood and Marrow Transplantation / Infectious Diseases
- Infectious Disease
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Academic Appointments
- Associate Professor - Med Center Line, Medicine - Division: Blood and Marrow Transplantation
- Member, Cancer Center
Clinical Focus- BMT
- Blood and Marrow Transplantation
- Hematology
Research InterestClinical research in allogeneic and autologous hematopoietic cell transplantation (HCT), more specifically, allogeneic transplantation and graft versus host disease. Exploring methods of improving prevention and treatment of GVHD as well as the long term follow-up and/or quality of life of affected patients.
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Academic Appointments
- Associate Professor - Med Center Line, Medicine - Division: Blood and Marrow Transplantation
- Member, Cancer Center
Clinical Focus- Blood and Marrow Transplantation
- Hematology
- Medical Oncology
Research Interesthaploidentical transplantation, follicular lymphoma, adoptive immunotherapy,supportive care
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Academic Appointments
- Associate Professor - Med Center Line, Medicine - Division: Blood and Marrow Transplantation
- Member, Cancer Center
Clinical Focus- Blood and Marrow Transplantation
- Hematology
Research InterestDr. Lowsky's research is focused on understanding the role of regulatory T cells in the prevention of GVHD and in promoting immune tolerance following organ transplantation.
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Academic Appointments
- Assistant Professor, Medicine - Division: Blood and Marrow Transplantation
- Member, Cancer Center
Clinical Focus- Aplastic Anemia
- Blood Stem Cell Transplant
- Blood and Marrow Transplantation
Research InterestInvestigates the targets of immune responses after human allogeneic stem cell transplantation. BMT patients develop antibodies against minor histocompatibility antigens (mHA) that are associated with chronic graft-v-host disease (cGVHD) and disease remission. Current projects: investigate Ab anti-tumor mechanism, high-throughput serologic identification of novel mHA in the development of GVHD and prevention of disease relapse, and clinical trials of B cell therapeutics for cGVHD.
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Academic Appointments
- Professor, Medicine - Division: Blood and Marrow Transplantation
- Member, Cancer Center
Clinical Focus- Blood and Marrow Transplantation
- Hematology
Research InterestOur labaratory focuses on the study of immune recognition by T and NK cells with special emphasis on graft vs host disease and graft vs tumor reactions. We utilize both murine and human systems in an effort to enhance graft vs tumor reactions while controlling graft vs host disease. We have developed bioluminescence models in collaboration with the Contag laboratory to study the trafficking of immune effector cells with a special emphasis on NK, T and regulatory T cells.
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Academic Appointments
- Visiting Associate Professor, Medicine - Division: Blood and Marrow Transplantation
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Academic Appointments
- Associate Professor, Medicine - Division: Blood and Marrow Transplantation
- Member, Cancer Center
Clinical Focus- Blood and Marrow Transplantation
- Hematology
Research InterestTransplantation of defined populations of allogeneic hematopoietic cells. Specifically, the way in which hematopoietic cell grafts alter antigen specific immune responses to allo-, auto- and viral antigens. The cellular and molecular basis of resistance to engraftment of allogeneic hematopoietic stem cells.
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Academic Appointments
- Assistant Professor - Med Center Line, Medicine - Division: Blood and Marrow Transplantation
- Member, Cancer Center
Clinical Focus- Cutaneous T-Cell Lymphoma
- Medical Oncology
Research InterestMy research interest is on immunotherapy of cancer. I have studies the mechanism of monoclonal antibody therapy of patients with lymphoma and am currently working on designing the next generation of engineered anti-tumor antibody based on the known mechanism to overcome resistance. I am also interested in tumor vaccine and plan to devise a novel strategy to use antibody-coated tumor cells/dendritic cells as a therpeutic vaccine.