Bryan Myers
Academic Appointments
- Emeritus Faculty, Acad Council, Medicine - Nephrology
Key Documents
Contact Information
- Academic Offices
Personal Information Email Tel (650) 725-4740
Scientific Focus
Current Research Interests
A differential solute clearance technique has been developed that characterizes the human glomerulus as an ultrafiltration membrane and macromolecular sieve. Filtration and plasma flow markers as well as probe macromolecules of varying size charge are used to determine glomerular ultrafiltration capacity and barrier selectivity in acute and chronic renal injuries. The physiologic characterization of glomerular capillary wall dysfunction is augmented by morphometric analysis of glomeruli from biopsy material. Serial physiologic and morphometric evaluation of several chronic glomerular diseases is being used to elucidate the pathogenesis of progression to renal failure in man. A similar approach that includes an analysis of pathobiology of postischemic injury to proximal tubules is being used to elucidate the mechanisms of filtration failure in acute renal failure.
Publications
- Debate: PRO Position. Formal assessment of donor kidney function should be mandatory. Am J Nephrol. 2011; (3): 198-200; discussion 205
- Rebuttal: PRO Position. Formal assessment of donor kidney function should be mandatory. Am J Nephrol. 2011; (3): 204
- Serum relaxin levels and kidney function in late pregnancy with or without preeclampsia. Clin Nephrol. 2011; (3): 226-32
- Effects of aging on glomerular function and number in living kidney donors. Kidney Int. 2010; (7): 686-92
- Glomerular function, structure, and number in renal allografts from older deceased donors. J Am Soc Nephrol. 2009; (1): 181-8
- Prediction of early progression in recently diagnosed IgA nephropathy. Nephrol Dial Transplant. 2008; (1): 213-22
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